Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   K6974_RS04735 Genome accession   NZ_CP082204
Coordinates   936678..938057 (+) Length   459 a.a.
NCBI ID   WP_029187994.1    Uniprot ID   A0A2I5N3K8
Organism   Streptococcus suis strain FJSM5     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 931678..943057
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K6974_RS04705 (K6974_04650) pstA 932000..932887 (+) 888 WP_014635996.1 phosphate ABC transporter permease PstA -
  K6974_RS04710 (K6974_04655) pstB 932912..933715 (+) 804 WP_002940866.1 phosphate ABC transporter ATP-binding protein PstB -
  K6974_RS04715 (K6974_04660) pstB 933727..934485 (+) 759 WP_172046551.1 phosphate ABC transporter ATP-binding protein PstB -
  K6974_RS04720 (K6974_04665) phoU 934514..935170 (+) 657 WP_024399033.1 phosphate signaling complex protein PhoU -
  K6974_RS04725 - 935320..935868 (+) 549 WP_029997972.1 hypothetical protein -
  K6974_RS04730 (K6974_04675) ciaR 936014..936685 (+) 672 WP_014637852.1 response regulator transcription factor Regulator
  K6974_RS04735 (K6974_04680) ciaH 936678..938057 (+) 1380 WP_029187994.1 cell wall metabolism sensor histidine kinase WalK Regulator
  K6974_RS04740 (K6974_04685) - 938158..939387 (+) 1230 WP_222336752.1 transglutaminase domain-containing protein -
  K6974_RS04745 (K6974_04690) rpsT 939640..939888 (-) 249 WP_012027069.1 30S ribosomal protein S20 -
  K6974_RS04750 (K6974_04695) coaA 939947..940867 (-) 921 WP_002935283.1 type I pantothenate kinase -
  K6974_RS04755 (K6974_04700) - 940976..941566 (+) 591 WP_024376492.1 class I SAM-dependent methyltransferase -
  K6974_RS04760 (K6974_04705) - 941563..942840 (+) 1278 WP_002940851.1 pyrimidine-nucleoside phosphorylase -

Sequence

Protein


Download         Length: 459 a.a.        Molecular weight: 52038.74 Da        Isoelectric Point: 6.5307

>NTDB_id=599988 K6974_RS04735 WP_029187994.1 936678..938057(+) (ciaH) [Streptococcus suis strain FJSM5]
MPKRFKKLMYTDKFSFFIRYFAVFTLIFGLMTAIIFQLMRSTMYQNSDNTLKRIKEEPVMAVGFAIARTYEPNSVFILQD
SPTSEETTSSSSDSMPVPKEQKNTRDGDQLRLGVNTHVLLYSKSGEMVNPDTFTGLADLPLDKEKLGEIKEAKVESSFGM
SEDYRYVTIELATDELGYYSSYDIKYATILVNVSQIKSSIETYESTVAIVMVSAWLISILASIYLSNLSMRPILISYQKQ
KDFVENASHELRTPLAVLQNRLESLFRHPEATILESSESIGSSLEEVRNMRLLTTNLLNLARRDDGLKVDMIDVQPNYFD
EIFANYLMIAEENGKTLTVNNLIHQPIRTDKVLIKQLLTILFDNAMKYTDDDGRIQITANIKDKSVYFTVADNGLGISDA
DKKKIFDRFYRVDKARTRQKGGFGLGLSLAQQIIKTLGGKISVRDNQPKGTIFEVGLPK

Nucleotide


Download         Length: 1380 bp        

>NTDB_id=599988 K6974_RS04735 WP_029187994.1 936678..938057(+) (ciaH) [Streptococcus suis strain FJSM5]
ATGCCTAAGCGATTTAAAAAATTAATGTACACGGATAAATTTTCCTTCTTTATCCGTTATTTTGCAGTATTTACCCTGAT
TTTTGGCTTGATGACAGCTATCATTTTTCAATTAATGCGTTCAACTATGTATCAAAATTCAGATAATACCTTGAAACGGA
TTAAGGAAGAACCAGTGATGGCTGTTGGTTTTGCGATCGCAAGAACCTATGAGCCCAACTCTGTCTTTATCCTTCAAGAT
AGCCCAACTAGTGAAGAAACGACGAGCTCTAGCTCAGATAGCATGCCTGTTCCTAAAGAACAAAAAAATACTAGAGATGG
AGATCAGCTGAGATTAGGTGTCAATACTCATGTCTTACTCTATAGTAAAAGTGGAGAAATGGTCAATCCGGATACTTTTA
CTGGTTTGGCCGACCTACCGTTAGATAAGGAAAAATTGGGCGAAATTAAGGAAGCAAAGGTTGAATCAAGCTTCGGTATG
TCTGAAGATTATCGCTATGTGACGATTGAGCTGGCTACAGATGAACTAGGTTATTATTCGTCCTATGATATAAAATATGC
GACAATTTTAGTGAATGTCAGCCAAATAAAATCCTCCATTGAGACCTATGAATCGACAGTTGCTATTGTTATGGTTTCAG
CTTGGCTCATTTCTATCTTAGCCAGTATTTACCTATCGAATCTTAGCATGCGTCCAATTCTAATTAGCTATCAAAAGCAA
AAAGACTTTGTTGAAAATGCTAGTCATGAGTTGCGTACGCCGTTGGCTGTTCTCCAAAATCGCTTGGAGAGCCTGTTTCG
CCATCCCGAAGCGACGATTTTAGAGAGTAGTGAAAGCATCGGATCTAGTTTGGAAGAAGTTCGAAATATGCGATTATTGA
CAACGAACCTACTCAATTTGGCTCGTCGTGATGATGGCTTAAAAGTCGATATGATTGATGTCCAACCCAACTATTTTGAT
GAAATCTTTGCTAATTACCTTATGATTGCTGAAGAAAATGGAAAAACACTAACAGTTAATAATTTGATTCATCAGCCGAT
TCGAACAGACAAGGTCCTGATTAAACAGTTGCTTACCATTTTATTTGACAATGCCATGAAGTATACCGACGATGATGGCA
GAATTCAAATTACAGCTAATATCAAGGATAAATCTGTCTACTTCACAGTTGCCGACAATGGTTTGGGAATCAGCGATGCT
GATAAGAAGAAAATCTTTGATCGCTTTTATCGAGTTGATAAGGCCAGAACGCGTCAAAAAGGTGGTTTCGGTCTAGGATT
ATCGCTGGCTCAGCAAATTATCAAGACACTAGGTGGGAAAATCTCTGTTAGAGATAACCAACCGAAAGGAACTATTTTTG
AGGTAGGATTACCTAAATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(240-306)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(350-458)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2I5N3K8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

50

99.782

0.499
  ciaH Streptococcus pneumoniae D39

50

99.782

0.499
  ciaH Streptococcus pneumoniae R6

50

99.782

0.499
  ciaH Streptococcus pneumoniae TIGR4

50

99.782

0.499
  ciaH Streptococcus mutans UA159

49.67

99.129

0.492