Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   K6974_RS02675 Genome accession   NZ_CP082204
Coordinates   496514..497806 (+) Length   430 a.a.
NCBI ID   WP_222337504.1    Uniprot ID   -
Organism   Streptococcus suis strain FJSM5     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 491514..502806
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K6974_RS02640 (K6974_02620) - 491820..492248 (+) 429 WP_161496995.1 DUF1366 domain-containing protein -
  K6974_RS02645 (K6974_02625) - 492252..492464 (+) 213 WP_004195045.1 hypothetical protein -
  K6974_RS02650 (K6974_02630) - 492468..492893 (+) 426 WP_172034999.1 hypothetical protein -
  K6974_RS02655 (K6974_02635) - 492895..493245 (+) 351 WP_044766575.1 phage holin -
  K6974_RS02660 (K6974_02640) - 493229..493915 (+) 687 WP_222337540.1 CHAP domain-containing protein -
  K6974_RS02665 (K6974_02645) - 494553..495674 (-) 1122 WP_015445098.1 IS110 family transposase -
  K6974_RS02670 (K6974_02650) - 495825..496457 (-) 633 WP_015646510.1 YigZ family protein -
  K6974_RS02675 (K6974_02655) comFA/cflA 496514..497806 (+) 1293 WP_222337504.1 DEAD/DEAH box helicase Machinery gene
  K6974_RS02680 (K6974_02660) comFC/cflB 497799..498464 (+) 666 WP_105146034.1 ComF family protein Machinery gene
  K6974_RS02685 (K6974_02665) hpf 498541..499083 (+) 543 WP_002941735.1 ribosome hibernation-promoting factor, HPF/YfiA family -

Sequence

Protein


Download         Length: 430 a.a.        Molecular weight: 48976.48 Da        Isoelectric Point: 9.1639

>NTDB_id=599982 K6974_RS02675 WP_222337504.1 496514..497806(+) (comFA/cflA) [Streptococcus suis strain FJSM5]
MKELENYYGRLFTKYQLTAKEREIAEKVPSITKKNNCFRCGTTFEEENKLPNDAYYCRACLLLGRVRSDEKLYHFPQKDF
SITKCLKWKGQLTDWQQRISDGLVANVENNRATLVHAVTGAGKTEMIYHTVASVIDKGGAVCLASPRIDVCIELYRRLQN
DFSVPISLLHGESEPYFRTPLVVATTHQLLKFYQAFDLVLIDEVDAFPYADNPMLYRAADNAVKEAGVQVFLTATSTDEL
DKKVRTGKLNRLSLPRRFHGNPLVVPQKVWFSKFDDTLKKNRLVPKLKKAIEEQRKSGFPLLIFVPEISKGQEFTKIMKK
TFPEETIGFVSSQTENRLEIVEGFRKREITVLISTTILERGVTFPCVDVFVVQANHYLYTSSSLVQIAGRVGRSMERPTG
LLQFYHEGSTGAIEKAIAEIKQMNKEAGYV

Nucleotide


Download         Length: 1293 bp        

>NTDB_id=599982 K6974_RS02675 WP_222337504.1 496514..497806(+) (comFA/cflA) [Streptococcus suis strain FJSM5]
ATGAAAGAATTAGAAAATTATTATGGAAGATTATTTACCAAATACCAATTGACAGCAAAAGAAAGAGAAATAGCAGAAAA
AGTGCCAAGTATTACAAAAAAGAATAACTGCTTTCGCTGTGGAACAACTTTTGAAGAAGAAAACAAATTGCCAAACGATG
CTTATTACTGTCGAGCCTGCTTGCTTCTAGGTAGAGTGCGGTCAGACGAAAAACTCTATCATTTTCCTCAGAAAGATTTT
TCAATCACTAAGTGTTTAAAGTGGAAAGGTCAATTAACTGATTGGCAACAAAGAATTTCAGATGGACTAGTTGCAAACGT
GGAAAATAATCGTGCGACATTGGTTCATGCAGTAACAGGAGCAGGTAAGACAGAAATGATCTACCACACCGTTGCCTCAG
TGATTGATAAAGGGGGAGCGGTTTGCCTAGCCAGTCCTCGAATTGATGTTTGTATAGAACTCTATAGACGTCTGCAAAAC
GACTTTTCAGTTCCAATTAGTTTACTGCATGGAGAGTCTGAACCCTATTTCAGAACTCCATTAGTTGTAGCAACCACACA
TCAGTTATTAAAATTTTATCAGGCCTTTGATTTGGTTTTGATTGATGAAGTAGACGCCTTTCCCTATGCAGATAATCCCA
TGCTCTATCGAGCAGCAGATAATGCGGTCAAGGAAGCCGGTGTTCAAGTTTTTCTGACAGCGACTTCAACAGATGAATTG
GATAAAAAAGTCAGAACGGGCAAATTAAACCGTCTTAGTTTGCCAAGGCGCTTTCATGGCAACCCACTTGTTGTCCCGCA
AAAAGTCTGGTTTAGTAAATTCGATGATACCCTAAAGAAAAATAGACTAGTTCCAAAGTTGAAAAAAGCGATTGAAGAAC
AGAGAAAGTCGGGCTTCCCCTTACTCATTTTTGTCCCAGAAATCTCTAAAGGTCAAGAATTTACCAAGATAATGAAAAAA
ACGTTCCCAGAAGAAACAATTGGCTTTGTATCCAGTCAAACAGAAAATCGCCTTGAAATAGTTGAAGGGTTTCGCAAGAG
AGAAATCACAGTCTTAATCTCGACTACTATTCTTGAACGTGGGGTGACCTTCCCATGTGTAGACGTCTTTGTTGTTCAAG
CCAATCATTACCTCTACACATCATCCAGTCTAGTGCAGATTGCAGGTCGGGTTGGTAGGAGTATGGAACGTCCGACTGGT
TTACTCCAGTTTTATCATGAGGGAAGTACAGGAGCCATTGAAAAGGCAATCGCTGAAATTAAACAGATGAACAAGGAGGC
TGGTTATGTCTAA

Domains

Predicted by InterproScan.

Type III restriction enzyme, res subunit (ResIII)

(91-235)

Helicase conserved C-terminal domain (Helicase_C)

(289-393)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus mitis NCTC 12261

66.821

100

0.67
  comFA/cflA Streptococcus pneumoniae Rx1

66.125

100

0.663
  comFA/cflA Streptococcus pneumoniae D39

66.125

100

0.663
  comFA/cflA Streptococcus pneumoniae R6

66.125

100

0.663
  comFA/cflA Streptococcus pneumoniae TIGR4

66.125

100

0.663
  comFA/cflA Streptococcus mitis SK321

65.893

100

0.66
  comFA Lactococcus lactis subsp. cremoris KW2

53.904

92.326

0.498
  comFA Latilactobacillus sakei subsp. sakei 23K

38.051

100

0.381
  comFA Bacillus subtilis subsp. subtilis str. 168

37.831

96.512

0.365