Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   K6972_RS04500 Genome accession   NZ_CP082203
Coordinates   896555..897934 (+) Length   459 a.a.
NCBI ID   WP_222812930.1    Uniprot ID   -
Organism   Streptococcus suis strain NJ3     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 891555..902934
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K6972_RS04470 (K6972_04470) pstA 891954..892841 (+) 888 WP_014635996.1 phosphate ABC transporter permease PstA -
  K6972_RS04475 (K6972_04475) pstB 892866..893669 (+) 804 WP_002940866.1 phosphate ABC transporter ATP-binding protein PstB -
  K6972_RS04480 (K6972_04480) pstB 893681..894439 (+) 759 WP_002937614.1 phosphate ABC transporter ATP-binding protein PstB -
  K6972_RS04485 (K6972_04485) phoU 894468..895124 (+) 657 WP_002937611.1 phosphate signaling complex protein PhoU -
  K6972_RS04490 (K6972_04490) - 895290..895697 (+) 408 WP_222812928.1 hypothetical protein -
  K6972_RS04495 (K6972_04495) ciaR 895891..896562 (+) 672 WP_009909965.1 response regulator transcription factor Regulator
  K6972_RS04500 (K6972_04500) ciaH 896555..897934 (+) 1380 WP_222812930.1 cell wall metabolism sensor histidine kinase WalK Regulator
  K6972_RS04505 (K6972_04505) - 898035..899264 (+) 1230 WP_222812931.1 transglutaminase domain-containing protein -
  K6972_RS04510 (K6972_04510) rpsT 899528..899776 (-) 249 WP_012027069.1 30S ribosomal protein S20 -
  K6972_RS04515 (K6972_04515) coaA 899835..900755 (-) 921 WP_002935283.1 type I pantothenate kinase -
  K6972_RS04520 (K6972_04520) - 900864..901454 (+) 591 WP_222812932.1 class I SAM-dependent methyltransferase -
  K6972_RS04525 (K6972_04525) - 901451..902728 (+) 1278 WP_105208334.1 pyrimidine-nucleoside phosphorylase -

Sequence

Protein


Download         Length: 459 a.a.        Molecular weight: 51990.69 Da        Isoelectric Point: 6.8979

>NTDB_id=599931 K6972_RS04500 WP_222812930.1 896555..897934(+) (ciaH) [Streptococcus suis strain NJ3]
MPKRFKKLMYTDKFSFFIRYFAVFTLIFGLMTAIIFQLMRSTMYQNSDNTLKRIRKEPALAVGFAIARTYEPNSVFILQD
SPTSEETTSSSSDSMPVPKDQKNTRDGDQLRLGVNTHVLLYSKSGEMVNPDTFTGLADLPLDKEKLGEIKEATVESSFGM
SEDYRYVTIELATDELGYYSSYDIKYATILVNVSQIKSSIETYESTVAIVMVSAWLISILASIYLSNLSMRPILISYQKQ
KDFVENASHELRTPLAVLQNRLESLFRHPEATILESSESIGSSLEEVRNMRLLTTNLLNLARRDDGLKVDMIDVQPNYFD
EIFANYLMIAEENGKILTVNNLIHQPIRTDKVLIKQLLTILFDNAMKYTDDDGRIQITANIKDKSVYFTVADNGLGISDA
DKKKIFDRFYRVDKARTRQKGGFGLGLSLAQQIIKTLGGKISVRDNQPKGTIFEVGLPK

Nucleotide


Download         Length: 1380 bp        

>NTDB_id=599931 K6972_RS04500 WP_222812930.1 896555..897934(+) (ciaH) [Streptococcus suis strain NJ3]
ATGCCTAAGCGATTTAAAAAATTAATGTACACGGATAAATTTTCTTTCTTTATCCGTTATTTTGCAGTATTTACTCTGAT
TTTTGGTTTAATGACAGCCATCATTTTTCAATTAATGCGTTCAACTATGTACCAAAATTCAGATAACACCTTGAAACGCA
TTAGGAAAGAACCAGCGCTGGCTGTTGGTTTTGCAATCGCAAGAACCTATGAGCCCAACTCTGTCTTTATACTTCAAGAT
AGCCCAACTAGTGAAGAAACGACGAGCTCTAGCTCAGATAGCATGCCTGTTCCTAAAGATCAAAAAAATACTAGAGATGG
AGATCAGCTGAGATTAGGTGTCAATACTCATGTCTTACTCTATAGTAAAAGTGGAGAAATGGTCAATCCGGATACTTTTA
CTGGTTTGGCCGACCTACCGTTAGATAAGGAAAAATTGGGCGAAATTAAGGAAGCAACGGTTGAATCAAGCTTCGGTATG
TCTGAAGATTATCGCTATGTGACGATTGAGCTGGCTACAGATGAACTAGGTTATTATTCGTCCTATGATATAAAATATGC
GACAATTTTAGTGAATGTCAGCCAAATAAAATCCTCCATTGAGACCTATGAATCGACAGTTGCTATTGTTATGGTATCAG
CTTGGCTCATTTCTATCTTGGCCAGTATTTACCTATCAAATCTTAGCATGCGTCCAATTCTAATCAGCTATCAAAAACAA
AAGGACTTTGTCGAAAATGCTAGTCATGAGTTGCGTACGCCGTTGGCTGTTCTCCAAAATCGTTTGGAGAGCCTGTTTCG
CCATCCCGAAGCGACGATTTTAGAGAGTAGTGAAAGCATCGGATCTAGTTTGGAAGAAGTCCGAAATATGCGATTATTGA
CAACGAACCTGCTCAATCTGGCTCGTCGTGATGATGGCTTAAAAGTCGATATGATCGATGTCCAGCCGAACTATTTTGAT
GAAATCTTTGCTAATTACCTTATGATTGCCGAAGAGAATGGAAAAATACTAACAGTTAATAATTTGATTCATCAGCCGAT
TCGAACAGATAAGGTCCTGATTAAACAGTTGCTCACCATTTTATTTGACAATGCCATGAAGTATACCGACGATGATGGCA
GAATTCAAATTACAGCTAATATCAAGGATAAATCTGTCTACTTCACAGTTGCCGACAATGGTTTGGGAATCAGCGATGCC
GATAAGAAGAAAATCTTTGATCGCTTTTATCGAGTTGATAAGGCCAGAACACGTCAAAAAGGTGGTTTCGGTCTAGGATT
ATCGTTGGCTCAGCAAATTATTAAGACACTAGGTGGGAAAATCTCTGTTAGAGATAACCAACCGAAAGGAACTATTTTTG
AGGTAGGATTACCTAAATAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(350-458)

His Kinase A (phospho-acceptor) domain (HisKA)

(240-306)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

49.46

100

0.499
  ciaH Streptococcus pneumoniae D39

49.46

100

0.499
  ciaH Streptococcus pneumoniae R6

49.46

100

0.499
  ciaH Streptococcus pneumoniae TIGR4

49.46

100

0.499
  ciaH Streptococcus mutans UA159

49.451

99.129

0.49