Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   K6976_RS04825 Genome accession   NZ_CP082202
Coordinates   965404..966783 (+) Length   459 a.a.
NCBI ID   WP_105115720.1    Uniprot ID   -
Organism   Streptococcus suis strain SS389     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 960404..971783
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K6976_RS04795 (K6976_04795) pstA 960704..961591 (+) 888 WP_014635996.1 phosphate ABC transporter permease PstA -
  K6976_RS04800 (K6976_04800) pstB 961616..962419 (+) 804 WP_024399032.1 phosphate ABC transporter ATP-binding protein PstB -
  K6976_RS04805 (K6976_04805) pstB 962431..963189 (+) 759 WP_002937614.1 phosphate ABC transporter ATP-binding protein PstB -
  K6976_RS04810 (K6976_04810) phoU 963218..963874 (+) 657 WP_222760109.1 phosphate signaling complex protein PhoU -
  K6976_RS04815 (K6976_04815) - 964040..964546 (+) 507 WP_024385292.1 hypothetical protein -
  K6976_RS04820 (K6976_04820) ciaR 964740..965411 (+) 672 WP_014637852.1 response regulator transcription factor Regulator
  K6976_RS04825 (K6976_04825) ciaH 965404..966783 (+) 1380 WP_105115720.1 cell wall metabolism sensor histidine kinase WalK Regulator
  K6976_RS04830 (K6976_04830) - 966884..968113 (+) 1230 WP_202848624.1 transglutaminase domain-containing protein -
  K6976_RS04835 (K6976_04835) rpsT 968376..968624 (-) 249 WP_012027069.1 30S ribosomal protein S20 -
  K6976_RS04840 (K6976_04840) coaA 968683..969603 (-) 921 WP_002940857.1 type I pantothenate kinase -
  K6976_RS04845 (K6976_04845) - 969712..970302 (+) 591 WP_024408790.1 class I SAM-dependent methyltransferase -
  K6976_RS04850 (K6976_04850) - 970299..971576 (+) 1278 WP_024389005.1 pyrimidine-nucleoside phosphorylase -

Sequence

Protein


Download         Length: 459 a.a.        Molecular weight: 51901.44 Da        Isoelectric Point: 6.1945

>NTDB_id=599879 K6976_RS04825 WP_105115720.1 965404..966783(+) (ciaH) [Streptococcus suis strain SS389]
MPKRIRKLVYTDKFSFFIRYFAVFTLIFGLMTAIIFQLMRSTMYQNSDNTLKRIKEEPAMAVGFAIARTYEPNSVFILQD
SPTSEETTSSSSDSTPVPKDQKNTRDGDQLRLGVNTHVLLYSKSGEMVNPDTFTGLADLPLDKEKLGEIKEATVESSFGM
SEDYRYVTIELATDELGYYSSYDIKYATILVNVSQIKSSIETYESTVAIVMVSAWLISILASIYLSNLSMRPILISYQKQ
KDFVENASHELRTPLAVLQNRLESLFRHPEATILESSESIGSSLEEVRNMRLLTTNLLNLARRDDGLKVDMIDVQPNYFD
EIFANYLMIAEENGKTLTVNNLIHQPIRTDKVLIKQLLTILFDNAMKYTDDDGRIQITANIKDKSVYFTVADNGLGISDA
DKKKIFDRFYRVDKARTRQKGGFGLGLSLAQQIIKTLGGKISVRDNQPKGTIFEVGLPK

Nucleotide


Download         Length: 1380 bp        

>NTDB_id=599879 K6976_RS04825 WP_105115720.1 965404..966783(+) (ciaH) [Streptococcus suis strain SS389]
ATGCCTAAGCGAATCAGAAAATTAGTGTATACGGATAAATTTTCCTTCTTTATCCGTTATTTTGCAGTATTTACCCTGAT
TTTTGGCTTGATGACAGCTATCATTTTTCAATTAATGCGTTCAACTATGTATCAAAATTCAGATAATACCTTGAAACGGA
TTAAGGAAGAACCAGCGATGGCTGTTGGTTTTGCAATCGCAAGAACCTATGAGCCCAACTCTGTCTTTATACTTCAAGAT
AGCCCAACTAGTGAAGAAACGACGAGCTCTAGCTCAGATAGCACGCCTGTTCCTAAAGATCAAAAAAATACTAGAGATGG
TGATCAGCTGAGATTAGGTGTCAATACTCATGTTTTACTCTATAGTAAAAGTGGAGAAATGGTCAATCCGGATACTTTTA
CTGGTTTGGCCGACCTACCGTTAGATAAGGAAAAATTGGGCGAAATTAAGGAAGCAACAGTTGAATCAAGCTTCGGTATG
TCTGAAGATTATCGCTATGTGACGATTGAGTTGGCTACAGATGAACTAGGTTATTATTCGTCCTATGATATAAAATATGC
GACAATTTTAGTGAATGTCAGCCAGATAAAATCCTCCATTGAGACCTATGAATCGACAGTTGCTATTGTTATGGTATCAG
CTTGGCTCATTTCTATCTTGGCCAGTATTTACCTATCAAATCTTAGCATGCGTCCAATTCTAATCAGCTATCAAAAACAA
AAGGACTTTGTCGAAAATGCTAGTCATGAGTTGCGTACGCCGCTGGCTGTTCTCCAAAATCGTTTGGAGAGCCTGTTTCG
CCATCCCGAAGCGACGATTTTAGAGAGTAGTGAAAGCATCGGATCTAGTTTGGAAGAAGTTCGAAATATGCGATTATTGA
CAACGAACCTGCTCAATTTGGCTCGTCGTGATGATGGCTTAAAAGTCGATATGATCGATGTCCAACCGAATTATTTTGAT
GAAATCTTTGCTAATTACCTTATGATTGCCGAAGAAAATGGAAAAACACTAACAGTTAATAATTTGATTCATCAGCCGAT
TCGAACAGACAAGGTCCTGATTAAACAGTTGCTCACCATTTTATTTGACAATGCCATGAAGTATACCGACGATGATGGCA
GAATTCAAATTACAGCTAATATCAAGGATAAATCTGTCTACTTCACAGTTGCCGACAATGGTTTGGGAATCAGCGATGCC
GATAAGAAGAAAATCTTTGATCGCTTTTATCGGGTTGATAAGGCCAGAACACGTCAAAAAGGTGGTTTCGGTCTAGGATT
ATCGTTGGCTCAGCAAATTATTAAGACACTAGGTGGGAAAATCTCTGTTAGAGATAACCAACCGAAAGGAACTATTTTTG
AGGTAGGATTACCTAAATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(240-306)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(350-458)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

49.46

100

0.499
  ciaH Streptococcus pneumoniae D39

49.46

100

0.499
  ciaH Streptococcus pneumoniae R6

49.46

100

0.499
  ciaH Streptococcus pneumoniae TIGR4

49.46

100

0.499
  ciaH Streptococcus mutans UA159

49.89

99.129

0.495