Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   K5J94_RS07250 Genome accession   NZ_CP081502
Coordinates   1526446..1527120 (-) Length   224 a.a.
NCBI ID   WP_159543977.1    Uniprot ID   -
Organism   Streptococcus halichoeri strain Shali_VAS-CPH     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1521446..1532120
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K5J94_RS07230 - 1522581..1523180 (-) 600 WP_159564009.1 class I SAM-dependent methyltransferase -
  K5J94_RS07235 coaA 1523461..1524381 (+) 921 WP_159543971.1 type I pantothenate kinase -
  K5J94_RS07240 rpsT 1524435..1524683 (+) 249 WP_167547760.1 30S ribosomal protein S20 -
  K5J94_RS07245 ciaH 1525149..1526453 (-) 1305 WP_159543975.1 cell wall metabolism sensor histidine kinase WalK Regulator
  K5J94_RS07250 ciaR 1526446..1527120 (-) 675 WP_159543977.1 response regulator transcription factor Regulator
  K5J94_RS07255 - 1527369..1529903 (-) 2535 WP_221912756.1 M1 family metallopeptidase -
  K5J94_RS07260 phoU 1529970..1530623 (-) 654 WP_159543981.1 phosphate signaling complex protein PhoU -
  K5J94_RS07265 pstB 1530658..1531416 (-) 759 WP_159544128.1 phosphate ABC transporter ATP-binding protein PstB -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25496.19 Da        Isoelectric Point: 4.3636

>NTDB_id=597075 K5J94_RS07250 WP_159543977.1 1526446..1527120(-) (ciaR) [Streptococcus halichoeri strain Shali_VAS-CPH]
MIKLLLVEDDLSLSNSIFDFLDDFADVMQVFDGEEGIFEAESGVYDLILLDLMLPGKNGFQVLKELREHGINTPVLIMTA
KESLDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRSGKMSDNHMTYGDIVVDLERNHVEAKGQEVELLGKEFDLLVY
FLQNQNVILPKSQIFDRLWGFDSDTTLSVVEVYVSKVRKKLKGTDFSTNLQTLRSVGYILKADD

Nucleotide


Download         Length: 675 bp        

>NTDB_id=597075 K5J94_RS07250 WP_159543977.1 1526446..1527120(-) (ciaR) [Streptococcus halichoeri strain Shali_VAS-CPH]
ATGATTAAGCTCTTACTGGTAGAAGATGACTTGAGTTTATCAAATTCCATTTTTGATTTTTTAGATGATTTTGCCGATGT
CATGCAGGTTTTTGATGGAGAAGAAGGTATTTTTGAAGCTGAAAGTGGTGTTTATGATCTGATTTTGCTTGATTTAATGT
TACCTGGAAAAAATGGTTTTCAGGTATTAAAAGAACTACGAGAGCACGGCATTAATACACCAGTTTTGATTATGACGGCT
AAAGAAAGCCTTGATGATAAGGGACACGGCTTTGAACTTGGGGCCGATGATTATCTGACCAAGCCTTTTTACTTGGAAGA
ATTAAAAATGCGCATCCAGGCCTTGTTAAAACGCTCGGGTAAAATGAGTGATAATCATATGACCTATGGTGATATTGTGG
TTGATTTAGAGCGAAATCATGTCGAAGCAAAAGGCCAAGAGGTCGAATTACTGGGAAAAGAATTTGATTTACTAGTGTAT
TTTTTACAAAATCAAAATGTTATCTTGCCAAAATCACAGATTTTTGATCGCCTTTGGGGGTTTGATAGTGATACAACTTT
ATCAGTTGTTGAAGTATATGTCTCCAAGGTCAGAAAGAAGCTCAAGGGCACAGATTTTTCGACTAATTTACAAACGTTAC
GGAGTGTAGGATATATTTTAAAGGCCGATGATTAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-220)

Response regulator receiver domain (Response_reg)

(5-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

86.425

98.661

0.853
  ciaR Streptococcus pneumoniae D39

86.425

98.661

0.853
  ciaR Streptococcus pneumoniae R6

86.425

98.661

0.853
  ciaR Streptococcus pneumoniae TIGR4

86.425

98.661

0.853
  ciaR Streptococcus mutans UA159

86.425

98.661

0.853