Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   M3M51_RS14015 Genome accession   NZ_CP097170
Coordinates   2934665..2935321 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain AR13438     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2929665..2940321
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M3M51_RS13985 (M3M51_13950) yecA 2930916..2931581 (-) 666 WP_000847877.1 UPF0149 family protein YecA -
  M3M51_RS14005 (M3M51_13970) pgsA 2932231..2932779 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  M3M51_RS14010 (M3M51_13975) uvrC 2932836..2934668 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  M3M51_RS14015 (M3M51_13980) letA 2934665..2935321 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  M3M51_RS14020 (M3M51_13985) yecU 2935616..2935792 (+) 177 WP_032245964.1 protein YecU -
  M3M51_RS14025 (M3M51_13990) yecF 2935779..2936003 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  M3M51_RS14030 (M3M51_13995) sdiA 2936070..2936792 (-) 723 WP_136479082.1 transcriptional regulator SdiA -
  M3M51_RS14035 (M3M51_14000) tcyN 2937022..2937774 (-) 753 WP_001273000.1 L-cystine ABC transporter ATP-binding protein TcyN -
  M3M51_RS14040 (M3M51_14005) tcyL 2937771..2938439 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  M3M51_RS14045 (M3M51_14010) dcyD 2938454..2939440 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=593789 M3M51_RS14015 WP_000611328.1 2934665..2935321(-) (letA) [Escherichia coli strain AR13438]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=593789 M3M51_RS14015 WP_000611328.1 2934665..2935321(-) (letA) [Escherichia coli strain AR13438]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGCCTTGAGGCAACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACTGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCTGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCTGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CATTAAGCCAGATCGAACCAGAAAAAACAGAAAGTCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACTAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482