Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   LDH51_RS05070 Genome accession   NZ_CP097001
Coordinates   1011755..1012414 (-) Length   219 a.a.
NCBI ID   WP_001221491.1    Uniprot ID   -
Organism   Escherichia coli strain NCCP 15734     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1006755..1017414
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LDH51_RS05045 - 1006959..1007711 (-) 753 WP_000619462.1 GntR family transcriptional regulator -
  LDH51_RS05050 - 1007998..1009329 (+) 1332 WP_000778883.1 MFS transporter -
  LDH51_RS05055 ygiN 1009373..1009687 (-) 315 WP_000958598.1 putative quinol monooxygenase -
  LDH51_RS05060 mdaB 1009718..1010299 (-) 582 WP_000065430.1 NADPH:quinone oxidoreductase MdaB -
  LDH51_RS05065 qseC 1010409..1011758 (-) 1350 WP_000673406.1 quorum sensing histidine kinase QseC -
  LDH51_RS05070 ciaR 1011755..1012414 (-) 660 WP_001221491.1 quorum sensing response regulator transcription factor QseB Regulator
  LDH51_RS05075 ygiW 1012566..1012958 (+) 393 WP_000712658.1 OB fold stress tolerance protein YgiW -
  LDH51_RS05080 ygiV 1013011..1013493 (+) 483 WP_000183494.1 GyrI-like domain-containing protein -
  LDH51_RS05085 mqsR 1013698..1013994 (+) 297 WP_045175177.1 type II toxin-antitoxin system toxin MqsR -
  LDH51_RS05090 mqsA 1013996..1014391 (+) 396 WP_000650107.1 type II toxin-antitoxin system antitoxin MqsA -
  LDH51_RS05095 ygiS 1014524..1016131 (+) 1608 WP_001324265.1 ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24745.66 Da        Isoelectric Point: 6.6540

>NTDB_id=593264 LDH51_RS05070 WP_001221491.1 1011755..1012414(-) (ciaR) [Escherichia coli strain NCCP 15734]
MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGRQGKEALYSAPYDAVILDLTLPGMDGRDILREWREKGQREPVLILTA
RDALAERVEGLRLGADDYLCKPFALIEVAARLEALMRRTNGQASNELRHGNVMLDPDKRIATLAGEPLTLKPKEFALLEL
LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGEK

Nucleotide


Download         Length: 660 bp        

>NTDB_id=593264 LDH51_RS05070 WP_001221491.1 1011755..1012414(-) (ciaR) [Escherichia coli strain NCCP 15734]
ATGCGAATTTTACTGATAGAAGATGACATGCTGATTGGCGACGGCATCAAAACGGGCCTTAGTAAAATGGGTTTTAGCGT
CGACTGGTTTACACAAGGTCGTCAGGGAAAAGAGGCGCTTTATAGCGCACCTTATGATGCGGTGATCCTGGATTTAACCT
TACCAGGCATGGATGGTCGCGATATTTTGCGCGAATGGCGAGAAAAAGGTCAGCGTGAGCCGGTACTGATCCTGACCGCG
CGCGATGCGCTGGCGGAACGTGTAGAAGGGCTGCGTCTGGGAGCTGACGATTATCTGTGTAAACCTTTTGCGTTGATAGA
AGTCGCCGCCAGGCTGGAAGCTCTGATGCGCCGAACCAACGGCCAGGCCAGCAACGAGCTGCGCCACGGTAACGTCATGC
TCGACCCCGACAAACGTATCGCCACGCTGGCTGGCGAACCCTTAACACTGAAACCAAAAGAATTTGCCCTGCTGGAATTA
CTGATGCGTAACGCTGGTCGGGTACTGCCGCGCAAACTGATTGAAGAGAAACTGTATACCTGGGACGAAGAGGTCACCAG
TAATGCCGTTGAAGTGCATGTGCATCATCTGCGACGCAAACTCGGTAGTGATTTTATTCGTACCGTGCATGGTATTGGCT
ACACATTAGGTGAGAAATGA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-216)

Response regulator receiver domain (Response_reg)

(3-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

38.326

100

0.397
  ciaR Streptococcus pneumoniae D39

38.326

100

0.397
  ciaR Streptococcus pneumoniae R6

38.326

100

0.397
  ciaR Streptococcus pneumoniae TIGR4

38.326

100

0.397
  ciaR Streptococcus mutans UA159

35.874

100

0.365
  micA Streptococcus pneumoniae Cp1015

34.498

100

0.361