Detailed information NTG0059109

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: MSA_RS02890
• Genome accession: NC_021486
• Coordinates: 515256..517517 (-)
• Length: 753 a.a.
• NCBI ID: WP_016480424.1
• Uniprot ID: -
• Organism: Streptococcus agalactiae ILRI005
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 510256..522517

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MSA_RS02870 (MSA_5880)	-	510286..511056 (+)	771	WP_001131467.1	DivIVA domain-containing protein	-
MSA_RS02875 (MSA_5890)	ileS	511340..514132 (+)	2793	WP_000768156.1	isoleucine--tRNA ligase	-
MSA_RS02880 (MSA_5900)	-	514249..514551 (-)	303	WP_001237035.1	DUF1827 family protein	-
MSA_RS02885 (MSA_5910)	-	514615..515070 (-)	456	WP_016480423.1	NUDIX hydrolase	-
MSA_RS02890 (MSA_5920)	clpE	515256..517517 (-)	2262	WP_016480424.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
MSA_RS02895 (MSA_5930)	-	517815..518045 (+)	231	WP_000443582.1	DUF1797 family protein	-
MSA_RS02900 (MSA_5940)	-	518187..518879 (+)	693	WP_001011647.1	amino acid ABC transporter permease	-
MSA_RS02905 (MSA_5950)	-	518872..519606 (+)	735	WP_000230128.1	amino acid ABC transporter ATP-binding protein	-
MSA_RS02910 (MSA_5960)	-	519892..521598 (+)	1707	WP_016480425.1	phospho-sugar mutase	-

Sequence

Protein

• Length: 753 a.a.
• Molecular weight: 83803.98 Da
• Isoelectric Point: 5.2771

>NTDB_id=59109 MSA_RS02890 WP_016480424.1 515256..517517(-) (clpE) [Streptococcus agalactiae ILRI005]
MLCQNCKLNESTIHLYTNVNGKQKQVDLCQNCYQIIKTDPNNPLFSGLNHVSHAPGGVNPFFDDFFGDLNNFRAFNGQDL
PNTPPTQSGGNRGGGNGNGRNNNRNQTATPPQAKGILEEFGINVTEIARHGDIDPVIGRDSEIIRVIEILNRRTKNNPVL
IGEPGVGKTAVVEGLAQKIVDGNVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRQRQDVILFIDEIHEIVG
AGTAGEGSMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPSVEETITILKGIQKKYEDYHHVKY
NNDAIEAAAVLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKEIDQRLIEAENLKAQATREEDYERAAYFRDQIAK
YKEMQQQKVDDQDTPIITEKTIEHIIEEKTNIPVGDLKEKEQSQLINLADDLKQHVIGQDDAVIKIAKAIRRNRVGLGSP
NRPIGSFLFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEKVRRNPYSLI
LLDEIEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGSGKTEANVGFGASREGRTNSVLGQLGNFFSPEF
MNRFDGIIEFKALDKENLLNIVDIMLSDVNARLAINGIHLDVTDKVKEKLVDLGYDPKMGARPLRRTIQEHIEDAITDYY
LENPSEKELRAIMTSNGNIIIKSSKKTEESTKG

Nucleotide

• Length: 2262 bp

>NTDB_id=59109 MSA_RS02890 WP_016480424.1 515256..517517(-) (clpE) [Streptococcus agalactiae ILRI005]
ATGCTCTGTCAAAACTGCAAACTAAACGAATCAACTATTCATTTGTATACAAATGTTAATGGAAAACAAAAGCAAGTTGA
TCTTTGTCAAAATTGCTACCAAATTATTAAAACTGACCCTAATAATCCACTTTTTTCAGGTTTAAATCATGTTTCACATG
CGCCTGGTGGCGTCAATCCTTTCTTTGATGATTTCTTTGGAGATTTAAATAATTTCAGAGCCTTTAATGGCCAAGATTTA
CCAAACACTCCTCCTACACAATCAGGAGGAAACCGAGGTGGAGGAAACGGTAATGGACGAAATAATAATCGCAACCAAAC
TGCAACTCCTCCTCAAGCCAAAGGGATTCTAGAAGAATTTGGTATCAATGTCACTGAAATAGCCCGCCATGGTGATATTG
ACCCTGTTATTGGACGTGACTCAGAAATTATTCGTGTTATCGAAATCCTTAATCGTCGTACAAAAAATAATCCTGTACTT
ATTGGTGAACCCGGCGTAGGGAAAACTGCTGTTGTTGAAGGACTTGCTCAGAAAATTGTTGATGGTAATGTGCCTCATAA
ACTTCAAGGCAAACAAGTTATTCGTTTGGATGTTGTGAGTCTAGTACAAGGAACGGGCATTCGTGGTCAATTTGAAGAAC
GCATGCAAAAGTTGATGGAAGAAATTCGTCAACGTCAAGATGTTATTCTATTCATAGATGAAATTCACGAAATAGTTGGA
GCTGGTACAGCTGGCGAAGGTAGTATGGATGCAGGTAATATTTTAAAACCTGCCCTTGCACGTGGAGAATTACAACTAGT
AGGTGCCACTACTCTCAATGAATATCGTATTATCGAAAAGGACGCTGCCTTAGAACGCCGTATGCAACCTGTAAAAGTCG
ATGAGCCTTCTGTTGAAGAAACCATTACTATTTTGAAAGGTATCCAAAAAAAATACGAAGATTATCATCACGTAAAATAT
AATAATGATGCCATAGAAGCAGCTGCAGTACTATCTAATCGTTATATCCAAGACCGCTTTTTACCTGATAAAGCAATAGA
CTTATTAGATGAAGCTGGTTCTAAAATGAACCTAACACTAAATTTTGTTGATCCAAAAGAAATTGATCAACGTCTCATTG
AAGCAGAAAATTTAAAAGCGCAAGCGACTCGTGAAGAAGATTACGAACGTGCAGCTTACTTCCGTGACCAGATTGCAAAA
TATAAAGAAATGCAACAACAAAAGGTCGACGATCAAGATACACCTATTATTACCGAAAAAACAATTGAGCACATCATTGA
AGAAAAAACGAATATCCCTGTTGGTGATTTAAAAGAAAAAGAACAATCTCAATTAATTAATCTCGCAGATGACTTGAAAC
AACATGTGATCGGCCAGGATGACGCTGTCATTAAGATTGCAAAAGCTATTCGTCGTAATCGAGTTGGTCTTGGTAGCCCA
AACCGTCCTATTGGTTCCTTTTTATTTGTAGGACCAACCGGTGTTGGTAAAACTGAACTTTCTAAACAACTAGCAATTGA
GCTCTTTGGTTCAGCTGATAGTATGATTCGTTTTGATATGTCAGAGTACATGGAAAAGCATGCTGTTGCTAAATTAGTCG
GAGCGCCTCCAGGATACGTGGGATACGAGGAAGCTGGACAATTAACTGAAAAGGTTCGTCGAAATCCTTACTCGCTCATC
CTTCTAGATGAAATTGAAAAAGCTCATCCCGATGTCATGCATATGTTCTTGCAAGTCCTTGATGACGGTCGATTAACAGA
TGGACAAGGAAGAACTGTTAGTTTTAAAGATACCATTATCATCATGACCTCAAATGCTGGTTCTGGTAAAACTGAAGCAA
ACGTTGGCTTTGGTGCCTCACGAGAAGGTAGGACGAATTCCGTACTAGGTCAACTAGGTAACTTCTTCAGCCCTGAATTT
ATGAACCGCTTTGACGGTATTATTGAATTCAAGGCTTTAGATAAAGAGAATCTCCTCAATATCGTTGATATTATGTTATC
TGACGTTAATGCACGTCTCGCCATCAATGGTATTCATCTAGATGTCACTGATAAAGTGAAAGAAAAATTGGTTGATTTAG
GTTACGATCCCAAAATGGGAGCACGTCCATTACGTCGTACTATTCAAGAACATATTGAAGATGCTATCACAGATTACTAT
CTTGAGAATCCAAGCGAAAAAGAACTTCGTGCTATTATGACTAGCAATGGAAATATCATAATAAAATCTTCTAAAAAAAC
TGAAGAAAGTACAAAAGGTTGA

Domains

Predicted by InterproScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (482-645)

• AAA lid domain (AAA_lid_9) (297-394)

• ATPase family associated with various cellular activities (AAA) (AAA) (159-276)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (653-727)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	85.676	100	0.858
clpE	Streptococcus pneumoniae Rx1	85.447	99.469	0.85
clpE	Streptococcus pneumoniae D39	85.447	99.469	0.85
clpE	Streptococcus pneumoniae R6	85.447	99.469	0.85
clpE	Streptococcus pneumoniae TIGR4	85.314	99.469	0.849
clpC	Lactococcus lactis subsp. cremoris KW2	74.734	99.867	0.746
clpC	Bacillus subtilis subsp. subtilis str. 168	51.18	90.04	0.461
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	47.528	83.267	0.396
clpC	Streptococcus pneumoniae Rx1	47.003	84.197	0.396
clpC	Streptococcus pneumoniae D39	47.003	84.197	0.396
clpC	Streptococcus pneumoniae TIGR4	46.845	84.197	0.394
clpC	Streptococcus mutans UA159	47.03	82.736	0.389
clpC	Streptococcus thermophilus LMD-9	46.276	83.798	0.388
clpC	Streptococcus thermophilus LMG 18311	45.959	83.798	0.385