Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilQ   Type   Machinery gene
Locus tag   KZH42_RS10335 Genome accession   NZ_CP079941
Coordinates   2073531..2075840 (+) Length   769 a.a.
NCBI ID   WP_002225652.1    Uniprot ID   Q70M91
Organism   Neisseria meningitidis strain C311     
Function   pseudopilus extrusion and retraction (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2068531..2080840
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KZH42_RS10315 (KZH42_10310) pilM 2070584..2071699 (+) 1116 WP_002214517.1 type IV pilus biogenesis protein PilM -
  KZH42_RS10320 (KZH42_10315) pilN 2071702..2072301 (+) 600 WP_002214520.1 PilN domain-containing protein Machinery gene
  KZH42_RS10325 (KZH42_10320) - 2072302..2072949 (+) 648 WP_002217908.1 type 4a pilus biogenesis protein PilO -
  KZH42_RS10330 (KZH42_10325) pilP 2072967..2073512 (+) 546 WP_002214522.1 pilus assembly protein PilP Machinery gene
  KZH42_RS10335 (KZH42_10330) pilQ 2073531..2075840 (+) 2310 WP_002225652.1 type IV pilus secretin PilQ Machinery gene
  KZH42_RS10340 (KZH42_10335) - 2076742..2077254 (+) 513 WP_002222978.1 shikimate kinase -
  KZH42_RS10345 (KZH42_10340) aroB 2077334..2078413 (+) 1080 WP_002221481.1 3-dehydroquinate synthase -
  KZH42_RS10350 (KZH42_10345) - 2079380..2080222 (+) 843 WP_002226675.1 class II glutamine amidotransferase -
  KZH42_RS10355 (KZH42_10350) nrdR 2080252..2080716 (+) 465 WP_002217912.1 transcriptional regulator NrdR -

Sequence

Protein


Download         Length: 769 a.a.        Molecular weight: 82473.09 Da        Isoelectric Point: 10.0982

>NTDB_id=590388 KZH42_RS10335 WP_002225652.1 2073531..2075840(+) (pilQ) [Neisseria meningitidis strain C311]
MNTKLTKIISGLFVATAAFQTASAGNITDIKVSSLPNKQKIVKVSFDKEIVNPTGFVTSSPARIALDFEQTGISMDQQVL
EYADPLLSKISAAQNSSRARLVLNLNKPGQYNTEVRGNKVWIFINESDDTVSAPARPAVKAAPAAPAKQQAAAPSTKSAV
SVSEPFTPAKQQAAAPFTESVVSVSAPFSPAKQQAAASAKQQAAAPAKQQAAAPAKQQAAAPAKQTNIDFRKDGKNAGII
ELAALGFAGQPDISQQHDHIIVTLKNHTLPTTLQRSLDVADFKTPVQKVTLKRLNNDTQLIITTAGNWELVNKSAAPGYF
TFQVLPKKQNLESGGVNNAPKTFTGRKISLDFQDVEIRTILQILAKESGMNIVASDSVNGKMTLSLKDVPWDQALDLVMQ
ARNLDMRQQGNIVNIAPRDELLAKDKALLQAEKDIADLGALYSQNFQLKYKNVEEFRSILRLDNADTTGNRNTLISGRGS
VLIDPATNTLIVTDTRSVIEKFRKLIDELDVPAQQVMIEARIVEAADGFSRDLGVKFGATGKKKLKNDTSAFGWGVNSGF
GGDDKWGAETKINLPITAAANSISLVRAISSGALNLELSASESLSKTKTLANPRVLTQNRKEAKIESGYEIPFTVTSIAN
GGSSTNTELKKAVLGLTVTPNITPDGQIIMTVKINKDSPAQCASGNQTILCISTKNLNTQAMVENGGTLIVGGIYEEDNG
NTLTKVPLLGDIPVIGNLFKTRGKKTDRRELLIFITPRIMGTAGNSLRY

Nucleotide


Download         Length: 2310 bp        

>NTDB_id=590388 KZH42_RS10335 WP_002225652.1 2073531..2075840(+) (pilQ) [Neisseria meningitidis strain C311]
ATGAATACCAAACTGACAAAAATCATTTCCGGTCTCTTTGTCGCAACCGCCGCCTTTCAGACAGCATCGGCAGGAAACAT
TACAGACATCAAAGTTTCCTCCCTGCCCAACAAACAGAAAATCGTCAAAGTCAGCTTTGACAAAGAGATTGTCAACCCGA
CCGGCTTCGTAACCTCCTCACCGGCCCGCATCGCCTTGGACTTTGAACAAACCGGCATTTCCATGGATCAACAGGTACTC
GAATATGCCGATCCTCTGTTGAGCAAAATCAGTGCCGCACAAAACAGCAGCCGTGCGCGTCTGGTTCTGAATCTGAACAA
ACCGGGCCAATACAATACCGAAGTACGCGGGAACAAAGTTTGGATATTCATTAACGAATCGGACGATACCGTGTCCGCCC
CCGCACGCCCCGCCGTAAAAGCCGCGCCTGCCGCACCGGCAAAACAACAGGCTGCCGCACCGTCTACCAAGTCCGCAGTA
TCCGTATCCGAACCCTTTACCCCGGCAAAACAACAGGCTGCCGCACCGTTTACCGAGTCCGTAGTATCCGTATCCGCACC
GTTCAGCCCGGCAAAACAACAGGCGGCGGCATCAGCAAAACAACAGGCGGCAGCACCAGCAAAACAACAGGCGGCAGCAC
CAGCAAAACAACAGGCGGCAGCACCAGCAAAACAAACCAATATCGATTTCCGCAAAGACGGCAAAAATGCCGGCATTATC
GAATTGGCTGCATTGGGCTTTGCCGGGCAGCCCGACATCAGCCAACAGCACGACCACATCATCGTTACGCTGAAAAACCA
TACCCTGCCGACCACGCTCCAACGCAGTTTGGATGTGGCAGACTTTAAAACACCGGTTCAAAAGGTTACGCTGAAACGCC
TCAATAACGACACCCAGCTGATTATCACAACAGCCGGCAACTGGGAACTCGTCAACAAATCCGCCGCGCCCGGATACTTT
ACCTTCCAAGTCCTGCCGAAAAAACAAAACCTCGAGTCAGGCGGCGTGAACAATGCGCCCAAAACCTTCACAGGCCGGAA
AATCTCCCTTGACTTCCAAGATGTCGAAATCCGCACCATCCTGCAGATTTTGGCAAAAGAATCCGGAATGAACATTGTTG
CCAGCGACTCCGTCAACGGCAAAATGACCCTCTCCCTCAAGGATGTGCCTTGGGATCAGGCTTTGGATTTGGTTATGCAG
GCGCGCAACCTCGATATGCGCCAGCAAGGGAATATCGTCAACATCGCGCCCCGCGACGAGCTGCTTGCCAAAGACAAAGC
CCTCTTACAGGCAGAAAAAGACATTGCCGATTTGGGTGCGCTGTATTCCCAAAACTTCCAGTTGAAATACAAAAATGTGG
AAGAATTCCGCAGCATCCTGCGTTTGGACAATGCCGACACGACCGGAAACCGCAACACGCTTATCAGCGGCAGGGGCAGC
GTGCTGATCGATCCCGCCACCAACACCCTGATTGTTACCGACACCCGCAGCGTCATCGAAAAATTCCGCAAACTGATTGA
CGAATTGGACGTACCCGCGCAACAAGTGATGATTGAGGCGCGTATCGTCGAAGCGGCAGACGGCTTCTCGCGCGATTTGG
GCGTTAAATTCGGCGCGACAGGCAAGAAAAAGCTGAAAAATGATACAAGCGCATTCGGCTGGGGGGTAAACTCCGGCTTC
GGCGGCGACGATAAATGGGGGGCCGAAACCAAAATCAACCTGCCGATTACCGCTGCCGCAAACAGCATTTCGCTGGTGCG
CGCGATTTCCTCCGGTGCCTTGAATTTGGAATTGTCCGCATCCGAATCGCTTTCAAAAACCAAAACGCTTGCCAATCCGC
GCGTGCTGACCCAAAACCGCAAAGAGGCCAAAATCGAATCCGGTTACGAAATTCCTTTCACCGTAACCTCAATCGCGAAC
GGCGGCAGCAGCACGAACACGGAACTCAAAAAAGCCGTCTTGGGGCTGACCGTTACGCCGAACATCACGCCCGACGGCCA
AATCATTATGACCGTCAAAATCAACAAGGACTCGCCTGCGCAATGTGCCTCCGGTAATCAGACGATCCTGTGTATTTCGA
CCAAAAACCTGAATACGCAGGCTATGGTTGAAAACGGCGGCACATTGATTGTCGGCGGTATTTATGAAGAAGACAACGGC
AATACGCTGACCAAAGTCCCCCTGTTGGGCGACATCCCCGTTATCGGCAACCTCTTTAAAACACGCGGGAAAAAAACCGA
CCGCCGCGAACTGCTGATTTTCATTACCCCGAGGATTATGGGTACGGCCGGCAACAGCCTGCGCTATTGA

Domains

Predicted by InterproScan.

Bacterial type II/III secretion system short domain (Secretin_N)

(444-515)

Bacterial type II and III secretion system protein (Secretin)

(601-760)

Secretin and TonB N terminus short domain (STN)

(371-416)

AMIN domain (AMIN)

(43-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  PDB 4AQZ
  PDB 4AV2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilQ Neisseria meningitidis MC58

100

100

1
  pilQ Neisseria meningitidis M1080

98.309

100

0.983
  pilQ Neisseria gonorrhoeae strain FA1090

91.157

100

0.912