Detailed information NTG0590110

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: KZB15_RS04315
• Genome accession: NZ_CP079922
• Coordinates: 873037..873990 (+)
• Length: 317 a.a.
• NCBI ID: WP_000495911.1
• Uniprot ID: Q8DQ27
• Organism: Streptococcus pneumoniae strain R36A
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 868037..878990

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KZB15_RS04290 (KZB15_04300)	rpmG	868780..868929 (+)	150	WP_001810029.1	50S ribosomal protein L33	-
KZB15_RS04295 (KZB15_04305)	secG	868969..869202 (+)	234	WP_000282517.1	preprotein translocase subunit SecG	-
KZB15_RS04300 (KZB15_04310)	rnr	869304..871658 (+)	2355	WP_000654897.1	ribonuclease R	-
KZB15_RS04305 (KZB15_04315)	smpB	871621..872088 (+)	468	WP_001051750.1	SsrA-binding protein SmpB	-
KZB15_RS04310 (KZB15_04320)	tehB	872104..872964 (+)	861	WP_000413762.1	SAM-dependent methyltransferase TehB	-
KZB15_RS04315 (KZB15_04325)	coiA	873037..873990 (+)	954	WP_000495911.1	competence protein CoiA	Machinery gene
KZB15_RS04320 (KZB15_04330)	pepF	874009..875811 (+)	1803	WP_000244122.1	oligoendopeptidase F	Regulator
KZB15_RS04325 (KZB15_04335)	-	875813..876526 (+)	714	WP_000230399.1	O-methyltransferase	-
KZB15_RS04330 (KZB15_04340)	prsA	876593..877534 (+)	942	WP_000727935.1	peptidylprolyl isomerase PrsA	-
KZB15_RS04335 (KZB15_04345)	-	877653..877994 (-)	342	Protein_875	transposase	-
KZB15_RS04340 (KZB15_04350)	-	878406..878501 (+)	96	Protein_876	IS630 family transposase	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 38143.79 Da
• Isoelectric Point: 9.1135

>NTDB_id=590110 KZB15_RS04315 WP_000495911.1 873037..873990(+) (coiA) [Streptococcus pneumoniae strain R36A]
MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTHFAHKSLKDCDFFFENESPEHLANKESLYHWLKKETK
VQLEYPLSELKQIADVFVNGNLALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
YVWELDKGKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKKQKISHFTVSEDKDICRYIRQQLYYQNLFWM
KEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIEQDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE

Nucleotide

• Length: 954 bp

>NTDB_id=590110 KZB15_RS04315 WP_000495911.1 873037..873990(+) (coiA) [Streptococcus pneumoniae strain R36A]
ATGTTTGTTGCGAGAGATGCTAGGGGAGAATTGGTAAATGTGTTAGAGGATAAACTTGAGAAGCAAGCATACACCTGCCC
AGCTTGTGGAGGCCAGCTCCATTTGCGTCAAGGACCAAGTGTACGGACGCATTTTGCCCATAAATCTTTAAAAGACTGTG
ATTTTTTCTTTGAAAATGAAAGTCCAGAACACCTGGCCAATAAGGAATCCCTCTATCACTGGTTGAAAAAAGAGACAAAG
GTTCAATTAGAGTACCCGCTTTCAGAACTTAAACAGATTGCGGATGTATTTGTAAATGGCAATCTAGCTCTAGAAGTTCA
GTGTAGTCCCTTGCCTCAGAAAGTCCTTAAAGAGCGAAGTGAGGGCTATCGTAGTCAGGGTTACCAAGTACTGTGGTTGC
TGGGTCAAAAACTGTGGCTCAAGGAGCGTTTGACTCGTCTACAGCAAGGTTTTCTTTATTTCAGTCAAAACATGGGCTTT
TATGTTTGGGAATTAGACAAGGGAAAACAAGTTTTAAGACTCAAATACCTGATTTACCAGGATCTCCGCGGTAAACTCCA
TTATCAAATCAAGGAATTTTCCTATGGCCAAGGTAGTTTATTGGAAATATTGCGTCTTCCCTATAAGAAACAAAAAATAT
CTCATTTTACAGTTTCTGAGGACAAGGACATCTGTCGCTATATCCGGCAACAACTTTATTATCAAAATCTCTTTTGGATG
AAAGAACAAGCAGAAGCCTATCAAAAGGGAGAAAATATCCTGACTTATGGACTGAAAGAATGGTATCCACAAATTCGACC
AATAGTGGGCAAATTTTTCCAGATTGAACAAGACTTGACTAGCTATTATCAGCACTTTTATACCTATTACCAAAAAAATC
CTCAAAATGATTGGCAAAAGCTTTATCCACCAGCCTTTTATCAGCAATATTTCTTGAAAAATATGGTAGAATAG

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (13-263)

3D structure

• AlphaFold DB: Q8DQ27

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus pneumoniae Rx1	100	100	1
coiA	Streptococcus pneumoniae D39	100	100	1
coiA	Streptococcus pneumoniae R6	100	100	1
coiA	Streptococcus pneumoniae TIGR4	99.369	100	0.994
coiA	Streptococcus mitis NCTC 12261	89.274	100	0.893
coiA	Lactococcus lactis subsp. cremoris KW2	42.593	100	0.435