Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   KX728_RS02375 Genome accession   NZ_CP079724
Coordinates   452157..452816 (-) Length   219 a.a.
NCBI ID   WP_215804919.1    Uniprot ID   -
Organism   Streptococcus oralis strain 34     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 447157..457816
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KX728_RS02345 (KX728_02340) - 447284..447850 (+) 567 WP_215804922.1 aminodeoxychorismate/anthranilate synthase component II -
  KX728_RS02350 (KX728_02345) trpD 447861..448865 (+) 1005 WP_215804921.1 anthranilate phosphoribosyltransferase -
  KX728_RS02355 (KX728_02350) trpC 448862..449629 (+) 768 WP_084944995.1 indole-3-glycerol phosphate synthase TrpC -
  KX728_RS02360 (KX728_02355) - 449616..450215 (+) 600 WP_049484654.1 phosphoribosylanthranilate isomerase -
  KX728_RS02365 (KX728_02360) trpB 450193..451416 (+) 1224 WP_000331263.1 tryptophan synthase subunit beta -
  KX728_RS02370 (KX728_02365) trpA 451409..452185 (+) 777 WP_215804920.1 tryptophan synthase subunit alpha -
  KX728_RS02375 (KX728_02370) cclA/cilC 452157..452816 (-) 660 WP_215804919.1 A24 family peptidase Machinery gene
  KX728_RS02380 (KX728_02375) - 452886..453341 (+) 456 WP_215804918.1 GNAT family N-acetyltransferase -
  KX728_RS02385 (KX728_02380) - 453499..454377 (-) 879 WP_215804917.1 SDR family NAD(P)-dependent oxidoreductase -
  KX728_RS02390 (KX728_02385) - 454379..455214 (-) 836 Protein_423 alpha/beta fold hydrolase -
  KX728_RS02395 (KX728_02390) - 455228..456232 (-) 1005 WP_215804916.1 NADP-dependent oxidoreductase -
  KX728_RS02400 (KX728_02395) - 456323..456754 (-) 432 WP_000379854.1 Rrf2 family transcriptional regulator -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 25185.56 Da        Isoelectric Point: 8.5892

>NTDB_id=588967 KX728_RS02375 WP_215804919.1 452157..452816(-) (cclA/cilC) [Streptococcus oralis strain 34]
MIDLYFFLVGSILASFLGLIIDRFPEQSIIRPASYCNSCQTRLRPLDLIPILSQVFNRFRCRYCKIRYPFWYALFELGLG
ILFLAWSWGWISLGQVILITAGLTLGIYDFRHQEYPLLVWMTFHLILMAFCSWNLVMVFFLILGIMAHFIDIRMGAGDFL
FLASCALIFSATELLILIQFASAAGILAFLLQKKKERLPFVPFLLLATCVIIFGKLLLV

Nucleotide


Download         Length: 660 bp        

>NTDB_id=588967 KX728_RS02375 WP_215804919.1 452157..452816(-) (cclA/cilC) [Streptococcus oralis strain 34]
ATGATTGATCTTTATTTTTTTCTTGTCGGGAGCATTCTCGCTTCTTTCTTGGGTTTGATCATTGACCGTTTCCCTGAGCA
ATCCATTATTCGACCGGCTAGCTACTGCAATTCCTGTCAGACTCGCTTGCGACCCTTAGATTTGATTCCTATCCTTTCGC
AGGTCTTCAATCGCTTTCGCTGTCGCTACTGCAAGATTCGATATCCATTCTGGTATGCCCTCTTTGAACTCGGCTTAGGA
ATCCTCTTTCTAGCTTGGTCTTGGGGCTGGATTTCCTTGGGTCAAGTCATCCTCATCACTGCTGGTTTGACCTTGGGCAT
CTACGACTTTCGCCATCAGGAATATCCCTTACTAGTCTGGATGACTTTCCACCTAATCCTCATGGCTTTCTGTAGTTGGA
ATCTGGTTATGGTCTTCTTCCTTATACTTGGAATCATGGCCCATTTTATCGATATTCGCATGGGCGCAGGGGATTTTCTC
TTTCTAGCTTCTTGTGCTCTCATCTTTAGCGCGACAGAATTACTCATCTTGATTCAGTTCGCTTCTGCGGCAGGCATTCT
GGCCTTTCTCCTGCAAAAGAAAAAGGAAAGACTTCCTTTTGTGCCTTTCCTCTTACTTGCTACTTGTGTGATTATTTTTG
GTAAGCTACTGCTTGTTTGA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-88)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus mitis SK321

89.954

100

0.9
  cclA/cilC Streptococcus pneumoniae Rx1

88.128

100

0.881
  cclA/cilC Streptococcus pneumoniae D39

88.128

100

0.881
  cclA/cilC Streptococcus pneumoniae R6

88.128

100

0.881
  cclA/cilC Streptococcus mitis NCTC 12261

87.671

100

0.877
  cclA/cilC Streptococcus pneumoniae TIGR4

87.671

100

0.877