Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   SA27298_RS09075 Genome accession   NZ_AP018548
Coordinates   1848217..1850163 (-) Length   648 a.a.
NCBI ID   WP_003032320.1    Uniprot ID   -
Organism   Streptococcus anginosus strain CCUG 27928     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1843217..1855163
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SA27298_RS09050 (SA27298_1845) cinA 1843456..1844727 (-) 1272 WP_003031814.1 competence/damage-inducible protein A Machinery gene
  SA27298_RS09055 (SA27298_1847) - 1845327..1845740 (+) 414 WP_018543619.1 EamA family transporter -
  SA27298_RS09060 (SA27298_1848) - 1845843..1846421 (-) 579 WP_003031817.1 DNA-3-methyladenine glycosylase I -
  SA27298_RS09065 (SA27298_1849) ruvA 1846432..1847022 (-) 591 WP_003031812.1 Holliday junction branch migration protein RuvA Machinery gene
  SA27298_RS09070 (SA27298_1850) - 1847093..1848028 (-) 936 WP_126438392.1 IS30 family transposase -
  SA27298_RS09075 (SA27298_1851) hexB 1848217..1850163 (-) 1947 WP_003032320.1 DNA mismatch repair endonuclease MutL Machinery gene
  SA27298_RS09080 (SA27298_1852) - 1850418..1850858 (+) 441 WP_003032335.1 LytTR family DNA-binding domain-containing protein -
  SA27298_RS09085 (SA27298_1853) - 1850855..1851313 (+) 459 WP_003032341.1 DUF3021 domain-containing protein -
  SA27298_RS09090 (SA27298_1854) hexA 1851502..1854063 (-) 2562 WP_018543668.1 DNA mismatch repair protein MutS Machinery gene
  SA27298_RS09095 (SA27298_1855) argR 1854321..1854761 (-) 441 WP_003027809.1 arginine repressor -

Sequence

Protein


Download         Length: 648 a.a.        Molecular weight: 73212.33 Da        Isoelectric Point: 5.0598

>NTDB_id=58866 SA27298_RS09075 WP_003032320.1 1848217..1850163(-) (hexB) [Streptococcus anginosus strain CCUG 27928]
MSKIIELPENLANQIAAGEVIERPSSVVKELIENSIDAGATQIIVEIEEAGLRSIQVIDNGEGIEHEEVSLALRRHATSK
IKKQADLFRIRTLGFRGEALPSIASVSRLTIETATSSGAHGTLLIAQGGEVETLEPSSCPRGTKIKVEDLFFNTPARLKY
MKSQQAELSHIVDVMNRLSLAHPEVAFTLVNDGKEMTRTAGTGNLRQAIAGIYGLTTAKKMIEISASDLDFEVSGYISLP
ELTRANRNYITILINGRYIKNFLLNRAILDGYGSKLMVGRFPIAVIDIRIDPYLADVNVHPTKQEVRISKERELMALISQ
AIAASLKEQDLIPDALENLAKSTINRAIKPEQTSLPLKENRLYYDKERNDFFVKPQVSEAQPSFEESARLDQQSADTDEL
NSKAASVKFAERQSPSYNQLDHPELDQASLERALDKLDGEETSTFPELEYFGQMHGTYLFAQGNGGLYIIDQHAAQERVK
YEYYREKIGDVDASQQQLLVPYIFEFPADDMLRLKQRMTLLEEVGVFLEEYGTNQFILREHPIWLKEEEIESAIYEMCDM
LLLTKEVSIKKYRAELAIMMSCKRSIKANHSLDDYSARDLIFQLSQCDNPYNCPHGRPVLVNFTKSDMEKMFRRIQENHT
SLRELGKY

Nucleotide


Download         Length: 1947 bp        

>NTDB_id=58866 SA27298_RS09075 WP_003032320.1 1848217..1850163(-) (hexB) [Streptococcus anginosus strain CCUG 27928]
ATGTCAAAAATTATTGAACTACCAGAAAATCTTGCTAATCAGATTGCAGCAGGTGAGGTCATCGAGCGACCTAGCAGCGT
GGTCAAGGAGTTGATAGAGAATTCCATTGATGCTGGTGCCACTCAGATTATAGTTGAGATTGAAGAAGCGGGACTCAGGA
GCATTCAAGTCATTGATAATGGTGAAGGAATTGAGCATGAGGAGGTTTCCTTGGCTTTGCGGCGGCATGCTACTAGTAAA
ATCAAGAAACAAGCCGACCTGTTTCGGATTCGGACATTGGGTTTTCGCGGTGAGGCGCTTCCGTCCATTGCCTCTGTTTC
ACGTTTGACGATTGAAACTGCGACAAGTAGTGGTGCACATGGAACGCTTCTGATTGCGCAAGGTGGAGAAGTTGAGACTT
TAGAGCCAAGTAGCTGTCCTAGGGGTACCAAAATCAAAGTGGAAGACCTTTTTTTCAACACGCCTGCTCGTTTGAAATAT
ATGAAAAGTCAACAAGCGGAACTATCTCATATTGTAGATGTGATGAATCGTTTGAGCTTGGCTCATCCGGAGGTCGCTTT
CACTCTTGTTAATGACGGTAAAGAGATGACACGGACAGCAGGAACAGGAAATCTGCGTCAAGCAATTGCTGGCATTTATG
GACTGACAACAGCCAAAAAAATGATTGAAATTTCAGCATCTGATTTGGATTTTGAAGTATCAGGCTATATTAGTTTGCCA
GAATTAACAAGGGCTAATCGGAATTACATTACTATTCTCATCAATGGTCGCTACATCAAGAATTTCCTACTCAATCGAGC
TATTTTAGATGGATATGGTAGCAAGCTCATGGTGGGACGTTTCCCGATTGCTGTGATTGATATTCGGATTGACCCATATC
TTGCTGATGTTAATGTTCACCCGACCAAGCAAGAAGTGCGGATTTCAAAGGAGCGAGAGCTCATGGCCTTGATATCGCAA
GCTATTGCTGCAAGTTTGAAAGAGCAAGATTTGATTCCGGACGCATTAGAGAATTTAGCCAAATCAACCATTAACCGAGC
AATTAAGCCTGAGCAGACCAGCCTCCCTCTCAAAGAGAACCGACTTTATTACGATAAAGAAAGAAATGACTTCTTTGTGA
AACCACAAGTGTCAGAAGCTCAACCTTCTTTTGAGGAATCTGCTCGATTAGATCAACAATCTGCTGATACAGATGAACTC
AATTCAAAAGCTGCTTCTGTCAAATTTGCAGAAAGACAATCTCCTTCTTACAATCAACTAGATCATCCAGAGCTGGATCA
GGCGAGCTTAGAGAGAGCTTTAGATAAGCTAGATGGAGAAGAAACTTCAACGTTTCCAGAATTGGAATATTTCGGGCAAA
TGCACGGCACCTACCTTTTTGCTCAAGGAAACGGTGGTCTTTATATTATTGACCAACATGCAGCTCAAGAGCGAGTAAAG
TACGAATATTACCGCGAAAAAATCGGAGATGTAGATGCTAGTCAGCAGCAGCTTCTGGTTCCCTATATCTTTGAATTTCC
AGCTGATGATATGTTGCGTCTGAAACAACGAATGACTCTTTTAGAAGAAGTCGGTGTTTTCCTTGAAGAATACGGAACTA
ATCAATTTATTCTTCGTGAACATCCCATTTGGCTTAAGGAAGAGGAGATCGAATCAGCTATTTATGAGATGTGCGATATG
CTGCTTCTAACCAAGGAAGTCTCTATCAAGAAATATCGCGCTGAGCTAGCTATTATGATGAGTTGCAAACGCTCTATTAA
AGCCAATCACAGTTTAGATGACTATTCAGCGCGTGATTTGATTTTTCAGTTATCACAATGCGACAATCCCTACAACTGCC
CTCACGGTCGTCCCGTTTTGGTCAACTTCACAAAATCTGATATGGAAAAAATGTTCCGTCGGATTCAGGAAAATCATACC
AGCCTGAGAGAATTGGGGAAATACTAA

Domains

Predicted by InterProScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-116)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)

MutL C terminal dimerisation domain (MutL_C)

(450-592)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

77.042

100

0.772

Multiple sequence alignment