Detailed information NTG0058867

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: SA27298_RS09090
• Genome accession: NZ_AP018548
• Coordinates: 1851502..1854063 (-)
• Length: 853 a.a.
• NCBI ID: WP_018543668.1
• Uniprot ID: -
• Organism: Streptococcus anginosus strain CCUG 27928
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 1846502..1859063

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SA27298_RS09070 (SA27298_1850)	-	1847093..1848028 (-)	936	WP_126438392.1	IS30 family transposase	-
SA27298_RS09075 (SA27298_1851)	hexB	1848217..1850163 (-)	1947	WP_003032320.1	DNA mismatch repair endonuclease MutL	Machinery gene
SA27298_RS09080 (SA27298_1852)	-	1850418..1850858 (+)	441	WP_003032335.1	LytTR family DNA-binding domain-containing protein	-
SA27298_RS09085 (SA27298_1853)	-	1850855..1851313 (+)	459	WP_003032341.1	DUF3021 domain-containing protein	-
SA27298_RS09090 (SA27298_1854)	hexA	1851502..1854063 (-)	2562	WP_018543668.1	DNA mismatch repair protein MutS	Machinery gene
SA27298_RS09095 (SA27298_1855)	argR	1854321..1854761 (-)	441	WP_003027809.1	arginine repressor	-
SA27298_RS09100 (SA27298_1856)	argS	1854865..1856553 (+)	1689	WP_003032324.1	arginine--tRNA ligase	-
SA27298_RS09105 (SA27298_1857)	nrdI	1856608..1857063 (-)	456	WP_003032317.1	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	-
SA27298_RS09110 (SA27298_1858)	-	1857139..1857648 (-)	510	WP_003032313.1	hypothetical protein	-

Sequence

Protein

• Length: 853 a.a.
• Molecular weight: 95877.51 Da
• Isoelectric Point: 5.1204

>NTDB_id=58867 SA27298_RS09090 WP_018543668.1 1851502..1854063(-) (hexA) [Streptococcus anginosus strain CCUG 27928]
MTKEKLSPGMQQYLDIKKDYPDAFLLFRMGDFYELFYDDATNAAQILEIALTSRNKNSENPIPMAGVPYHSVQQYIDVLI
EAGYKVAIAEQMEDPKKAVGVVKREVVQVITPGTVVDSSKPDSQNNFLVALDKLSGIYGLAYMDVGTGEFQVTSLSDFNI
VCGEIRNLRAREVVLGYELPEMERQVLETQMTLLLSQVETTFDDVQLLGKDLSPLEHQVAGKLLQYVHKTQLRELSHLKQ
VHHYEIKDFLQMDYSTMASLDLTENARTGKKHGSLYWLMDDTKTAMGTRLLRAWIQRPLIDKERIVKRQDVVQVFLDHFF
ERSDLSDTLKGVYDIERLASRVSFGKTNPKDLLQLAATLSHVPQIKGILKGIDSPVLEDLIAKLDEIPELASLIQSAISP
DASNVITEGNIIKTGFDETLDKYRVVMRDGTSWIADIEAKEREASGINNLKIDYNKKDGYYFHVTNSQLEHVPSHFFRKA
TLKNSERFGTEELARIEGEMLEAREKSANLEYEIFMRIREEAGKYIKRLQSLAQTLATVDVLQSFAAVAEKQHFVRPEFI
EQRSIQIDKGRHAVVEKVMGAQTYIPNSISMDENVNVQLITGPNMSGKSTYMRQLAIIVIMAQMGSYVSAESAQLPIFDA
IFTRIGAADDLVSGQSTFMVEMMEANHAISQATENSLILFDELGRGTATYDGMALAQAIIEYIHNRTGAKTLFATHYHEL
TELSTSLTQLENVHVATLEKDGQVTFLHKIEVGPADKSYGIHVAKIAGLPNDLLTRANQILTRLESQANEKSSFGISNTL
PAAAREKNQVAEQMSLFTETTESPILDELRQLDIYNMTPMEVMLAVAEIKKKL

Nucleotide

• Length: 2562 bp

>NTDB_id=58867 SA27298_RS09090 WP_018543668.1 1851502..1854063(-) (hexA) [Streptococcus anginosus strain CCUG 27928]
ATGACAAAAGAAAAACTATCTCCAGGAATGCAACAGTATTTAGATATAAAAAAAGATTATCCAGATGCTTTTTTGCTATT
TCGCATGGGAGATTTTTATGAATTATTCTATGATGATGCGACCAATGCGGCACAGATTTTAGAGATTGCTCTGACTAGTC
GCAATAAAAACTCGGAAAATCCAATCCCAATGGCAGGAGTTCCTTACCATTCAGTGCAGCAATACATTGATGTTTTAATT
GAAGCAGGCTATAAAGTTGCGATTGCAGAGCAAATGGAAGATCCTAAAAAAGCGGTTGGAGTAGTCAAACGCGAAGTAGT
ACAGGTGATTACGCCGGGGACAGTAGTTGATTCTTCAAAACCAGACAGTCAGAATAACTTTTTAGTGGCTTTGGATAAGC
TGTCAGGTATATATGGACTGGCTTATATGGATGTGGGAACGGGTGAATTTCAGGTCACAAGTCTTAGTGACTTTAACATA
GTCTGTGGAGAAATCCGAAACTTGCGAGCGCGTGAAGTGGTCTTAGGGTATGAATTGCCTGAAATGGAGCGCCAAGTATT
GGAGACTCAAATGACTCTCCTTTTATCGCAAGTAGAAACTACATTTGATGATGTTCAGCTACTAGGAAAGGACTTGTCAC
CGCTAGAGCACCAAGTAGCTGGAAAGTTATTACAGTATGTTCATAAAACGCAGCTACGTGAGCTTAGTCATTTGAAACAA
GTTCATCATTATGAAATCAAAGATTTCTTGCAGATGGACTACTCAACTATGGCAAGTCTGGATTTAACAGAGAATGCTCG
GACAGGAAAGAAGCACGGGAGCCTTTATTGGCTGATGGATGATACCAAGACAGCTATGGGAACACGATTGTTGAGAGCGT
GGATTCAACGTCCGTTGATTGATAAAGAGCGAATCGTCAAGCGGCAGGATGTAGTGCAAGTCTTTTTAGATCATTTCTTT
GAGCGCAGTGACTTATCAGACACTCTCAAAGGAGTGTATGATATTGAGCGTTTAGCCAGTCGGGTTTCGTTTGGCAAGAC
CAATCCAAAAGATTTATTACAACTTGCTGCGACATTGAGTCATGTACCACAAATTAAGGGAATCTTAAAAGGAATTGACA
GCCCAGTTTTGGAAGATTTGATTGCCAAATTGGATGAAATTCCTGAACTGGCGTCCTTAATTCAGTCAGCAATTTCGCCG
GATGCTTCAAATGTCATTACAGAGGGTAATATTATTAAAACAGGTTTTGATGAAACCTTGGATAAATATCGAGTGGTTAT
GCGAGATGGAACGAGCTGGATTGCAGATATTGAGGCGAAAGAAAGAGAAGCCAGTGGAATTAACAACCTGAAGATTGATT
ACAATAAAAAAGATGGTTATTATTTTCATGTCACAAATTCCCAGCTTGAACACGTTCCCAGTCATTTTTTCCGCAAGGCA
ACTCTGAAAAATTCAGAGCGTTTTGGTACGGAAGAACTGGCTCGTATTGAAGGGGAGATGTTGGAAGCGCGTGAAAAATC
AGCTAATTTGGAATACGAGATTTTTATGCGCATTCGTGAGGAAGCTGGTAAGTATATCAAACGCCTGCAATCCTTGGCAC
AAACTCTGGCAACGGTTGATGTGCTGCAAAGCTTTGCAGCTGTAGCTGAAAAGCAACACTTTGTGAGACCAGAATTTATT
GAGCAACGCTCTATCCAAATTGATAAAGGGCGGCATGCGGTCGTAGAAAAAGTTATGGGTGCACAAACCTATATTCCTAA
TAGCATTTCAATGGATGAGAATGTTAATGTTCAACTAATTACAGGTCCAAATATGAGTGGGAAGTCAACTTATATGCGGC
AGTTAGCAATTATTGTGATTATGGCTCAAATGGGCTCTTATGTTTCAGCTGAAAGCGCTCAATTGCCGATTTTTGATGCA
ATCTTTACTCGAATTGGTGCAGCTGATGACTTGGTTTCTGGACAATCAACCTTTATGGTTGAAATGATGGAAGCAAACCA
TGCTATTTCTCAAGCAACAGAAAATTCACTTATTCTTTTTGATGAGTTAGGAAGAGGAACAGCGACCTATGATGGCATGG
CGCTTGCTCAAGCTATTATTGAGTATATTCACAATCGGACAGGAGCCAAGACACTTTTTGCGACTCACTATCACGAGTTG
ACAGAACTGTCAACTAGCTTGACACAACTAGAAAATGTCCATGTAGCAACCCTAGAAAAAGATGGTCAAGTAACATTTCT
TCATAAGATTGAGGTTGGACCTGCTGATAAATCTTATGGGATTCATGTAGCAAAAATTGCAGGTTTGCCAAATGATTTGT
TGACAAGAGCGAATCAAATATTGACACGATTAGAAAGCCAAGCAAATGAGAAGTCATCTTTTGGCATCTCTAATACATTG
CCTGCGGCTGCTCGTGAAAAAAATCAAGTGGCTGAGCAGATGTCTTTATTTACAGAAACAACTGAATCACCTATTTTAGA
CGAGTTGCGCCAGTTGGACATTTATAATATGACCCCAATGGAAGTGATGTTGGCTGTGGCAGAGATAAAGAAGAAACTTT
AA

Domains

Predicted by InterProScan.

• MutS domain III (MutS_III) (255-546)

• MutS domain V (MutS_V) (599-785)

• MutS domain I (MutS_I) (8-118)

• MutS domain II (MutS_II) (126-239)

• MutS family domain IV (MutS_IV) (415-505)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	76.202	100	0.762
mutS	Pseudomonas stutzeri strain ATCC 17587	36.385	100	0.368