Detailed information    

insolico Bioinformatically predicted

Overview


Name   comGC/cglC   Type   Machinery gene
Locus tag   KVY10_RS07885 Genome accession   NZ_CP078162
Coordinates   1642911..1643186 (-) Length   91 a.a.
NCBI ID   WP_002356991.1    Uniprot ID   A0A1B4XPV0
Organism   Enterococcus faecalis strain NS2     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 1637911..1648186
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KVY10_RS07850 (KVY10_07850) - 1638466..1638939 (+) 474 WP_002357065.1 universal stress protein -
  KVY10_RS07855 (KVY10_07855) - 1639051..1640238 (-) 1188 WP_002357064.1 acetate/propionate family kinase -
  KVY10_RS07860 (KVY10_07860) - 1640263..1641270 (-) 1008 WP_002357063.1 class I SAM-dependent methyltransferase -
  KVY10_RS07865 (KVY10_07865) comGG 1641399..1641752 (-) 354 WP_033626584.1 competence type IV pilus minor pilin ComGG -
  KVY10_RS07870 (KVY10_07870) comGF 1641752..1642186 (-) 435 WP_002362055.1 competence type IV pilus minor pilin ComGF -
  KVY10_RS07875 (KVY10_07875) - 1642176..1642502 (-) 327 WP_002370967.1 type II secretion system protein -
  KVY10_RS07880 (KVY10_07880) comGD 1642468..1642914 (-) 447 WP_002366895.1 competence type IV pilus minor pilin ComGD -
  KVY10_RS07885 (KVY10_07885) comGC/cglC 1642911..1643186 (-) 276 WP_002356991.1 competence type IV pilus major pilin ComGC Machinery gene
  KVY10_RS07890 (KVY10_07890) comGB 1643186..1644232 (-) 1047 WP_218391168.1 competence type IV pilus assembly protein ComGB -
  KVY10_RS07895 (KVY10_07895) comGA 1644189..1645157 (-) 969 WP_002364362.1 competence type IV pilus ATPase ComGA -
  KVY10_RS07900 (KVY10_07900) - 1645397..1646725 (-) 1329 WP_002362058.1 APC family permease -
  KVY10_RS07905 (KVY10_07905) rlmN 1647015..1648088 (-) 1074 WP_002356987.1 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN -

Sequence


Protein


Download         Length: 91 a.a.        Molecular weight: 10464.41 Da        Isoelectric Point: 9.3192

>NTDB_id=587455 KVY10_RS07885 WP_002356991.1 1642911..1643186(-) (comGC/cglC) [Enterococcus faecalis strain NS2]
MKKKQKYAGFTLLEMLIVLLIISVLILLFVPNLAKHKETVDKKGNEAIVKIVESQIELYTLEKNKTPSLNELVNEGYITK
EQLDKYTAEKQ

Nucleotide


Download         Length: 276 bp        

>NTDB_id=587455 KVY10_RS07885 WP_002356991.1 1642911..1643186(-) (comGC/cglC) [Enterococcus faecalis strain NS2]
ATGAAAAAGAAACAAAAATACGCAGGGTTTACATTATTAGAAATGTTGATTGTCTTATTGATTATTTCCGTATTGATTTT
ACTTTTTGTTCCTAACTTAGCGAAACATAAAGAAACAGTTGATAAAAAAGGCAATGAAGCAATCGTAAAAATTGTAGAAT
CACAAATCGAGCTCTACACACTAGAAAAAAATAAGACGCCTTCTTTAAATGAATTAGTCAACGAAGGCTACATTACTAAA
GAGCAGTTAGATAAATATACAGCAGAAAAGCAATGA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB A0A1B4XPV0

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus pneumoniae Rx1

63.095

92.308

0.582

  comGC/cglC Streptococcus pneumoniae D39

63.095

92.308

0.582

  comGC/cglC Streptococcus pneumoniae R6

63.095

92.308

0.582

  comGC/cglC Streptococcus pneumoniae TIGR4

63.095

92.308

0.582

  comGC/cglC Streptococcus mitis NCTC 12261

61.905

92.308

0.571

  comGC/cglC Streptococcus mitis SK321

61.176

93.407

0.571

  comGC Lactococcus lactis subsp. cremoris KW2

58.14

94.505

0.549

  comYC Streptococcus gordonii str. Challis substr. CH1

56.322

95.604

0.538

  comYC Streptococcus suis isolate S10

52.326

94.505

0.495

  comYC Streptococcus mutans UA159

57.692

85.714

0.495

  comYC Streptococcus mutans UA140

57.692

85.714

0.495

  comGC Latilactobacillus sakei subsp. sakei 23K

46.154

100

0.462

  comGC Staphylococcus aureus MW2

46.835

86.813

0.407

  comGC Staphylococcus aureus N315

46.835

86.813

0.407

  comGC Bacillus subtilis subsp. subtilis str. 168

48.649

81.319

0.396