Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilR   Type   Regulator
Locus tag   KUU78_RS24945 Genome accession   NZ_CP077971
Coordinates   5302919..5304256 (+) Length   445 a.a.
NCBI ID   WP_222822314.1    Uniprot ID   -
Organism   Pseudomonas aeruginosa strain ZPPH33     
Function   regulate pilin expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 5297919..5309256
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KUU78_RS24920 (KUU78_24905) pgeF 5298062..5298790 (-) 729 WP_003102588.1 peptidoglycan editing factor PgeF -
  KUU78_RS24925 (KUU78_24910) rluD 5298787..5299749 (-) 963 WP_003094686.1 23S rRNA pseudouridine(1911/1915/1917) synthase RluD -
  KUU78_RS24930 (KUU78_24915) - 5299895..5300920 (+) 1026 WP_003102590.1 outer membrane protein assembly factor BamD -
  KUU78_RS24935 (KUU78_24920) - 5301077..5301322 (+) 246 WP_003102591.1 PP0621 family protein -
  KUU78_RS24940 (KUU78_24925) pilS 5301312..5302904 (+) 1593 WP_003123394.1 two-component system sensor histidine kinase PilS Regulator
  KUU78_RS24945 (KUU78_24930) pilR 5302919..5304256 (+) 1338 WP_222822314.1 two-component system response regulator PilR Regulator
  KUU78_RS24950 (KUU78_24935) thiO 5304302..5305396 (-) 1095 WP_023108762.1 glycine oxidase ThiO -
  KUU78_RS24955 (KUU78_24940) - 5305530..5306039 (+) 510 WP_017002065.1 Tfp pilus assembly protein FimT/FimU -
  KUU78_RS24960 (KUU78_24945) - 5306145..5306651 (+) 507 WP_003102598.1 Tfp pilus assembly protein FimT/FimU -
  KUU78_RS24965 (KUU78_24950) pilV 5306642..5307199 (+) 558 WP_003119423.1 type 4a pilus minor pilin PilV Machinery gene
  KUU78_RS24970 (KUU78_24955) pilW 5307196..5308020 (+) 825 WP_003119422.1 type 4a pilus minor pilin PilW -
  KUU78_RS24975 (KUU78_24960) pilX 5308017..5308604 (+) 588 WP_003112826.1 type 4a pilus minor pilin PilX -

Sequence

Protein


Download         Length: 445 a.a.        Molecular weight: 49755.09 Da        Isoelectric Point: 5.8654

>NTDB_id=585796 KUU78_RS24945 WP_222822314.1 5302919..5304256(+) (pilR) [Pseudomonas aeruginosa strain ZPPH33]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAMEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide


Download         Length: 1338 bp        

>NTDB_id=585796 KUU78_RS24945 WP_222822314.1 5302919..5304256(+) (pilR) [Pseudomonas aeruginosa strain ZPPH33]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAGACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTGGTGGCAACCGCCCTGCGCTTGCGCAACCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGTAGCGGCAAGGAGCTGGTGGCGCGCCTGATCCACGAGCAGGGGCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAACTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATGGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGCGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGGGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCGCCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGAACGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAGAAGCTGAAGAACTACCG
CTTCCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTACACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCCGCGAGCCTGAGCGAAATAGACAACCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCGCTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

Sigma-54 interaction domain (Sigma54_activat)

(135-301)

Response regulator receiver domain (Response_reg)

(7-115)

Bacterial regulatory protein, Fis family (HTH_8)

(402-442)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilR Pseudomonas aeruginosa PAK

99.775

100

0.998
  pilR Acinetobacter baumannii strain A118

51.198

100

0.528
  luxO Vibrio cholerae strain A1552

38.17

100

0.384