Detailed information NTG0058574

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: MDRSPN_RS09345
• Genome accession: NZ_AP018391
• Coordinates: 1771243..1772142 (-)
• Length: 299 a.a.
• NCBI ID: WP_120164277.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain MDRSPN001
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1766243..1777142

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MDRSPN_RS09330 (MDRSPN_01771)	rsmA	1766893..1767765 (-)	873	WP_001216856.1	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA	-
MDRSPN_RS11385	-	1768016..1768309 (-)	294	Protein_1764	hypothetical protein	-
MDRSPN_RS09335 (MDRSPN_01773)	-	1768302..1768943 (-)	642	WP_000565531.1	ABC transporter ATP-binding protein	-
MDRSPN_RS09340 (MDRSPN_01774)	-	1768945..1770975 (-)	2031	WP_000825271.1	bacteriocin-associated integral membrane family protein	-
MDRSPN_RS09345 (MDRSPN_01775)	comR	1771243..1772142 (-)	900	WP_120164277.1	helix-turn-helix transcriptional regulator	Regulator
MDRSPN_RS09350 (MDRSPN_01776)	rnmV	1772214..1772774 (-)	561	WP_000660013.1	ribonuclease M5	-
MDRSPN_RS09355 (MDRSPN_01777)	-	1772774..1773547 (-)	774	WP_000575650.1	TatD family hydrolase	-
MDRSPN_RS09365 (MDRSPN_01778)	-	1773852..1774823 (-)	972	Protein_1770	DUF1542 domain-containing protein	-
MDRSPN_RS09375 (MDRSPN_01779)	rpmH	1775029..1775163 (-)	135	WP_000831905.1	50S ribosomal protein L34	-
MDRSPN_RS09380 (MDRSPN_01780)	-	1775308..1776522 (-)	1215	WP_000666484.1	pyridoxal phosphate-dependent aminotransferase	-
MDRSPN_RS09385 (MDRSPN_01781)	-	1776678..1776970 (-)	293	Protein_1773	hypothetical protein	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35390.11 Da
• Isoelectric Point: 4.6674

>NTDB_id=58574 MDRSPN_RS09345 WP_120164277.1 1771243..1772142(-) (comR) [Streptococcus pneumoniae strain MDRSPN001]
MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPSLPKLDYIARRLGVPVYGLMPDFSALPPAYLELKYQI
LREPIYGKEEEYDKKEACLEEIYKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMPQIIEKEVYSTNDMLL
IRLFFYQMLIRKDLAKFINQIEELMLFLLEQKKVTKLENFFIIRDTLISGMCCLEKVGVTDCFNDYLSCLQEIMDKTQDY
QKKPLVFMFLWKQALREERDFSLAESFYQSSKTFAQLIGDEFLVKKLTEEWQEDVKKYL

Nucleotide

• Length: 900 bp

>NTDB_id=58574 MDRSPN_RS09345 WP_120164277.1 1771243..1772142(-) (comR) [Streptococcus pneumoniae strain MDRSPN001]
ATGTTAATTGGTCAAAAAATTAAAGAGATTCGGATAGAAAAAGGAATTAGTCGTCCAGATTTTTGTGGAGATGAGCAAGA
ACTGACAGTTCGTCAACTGTCGCGAATTGAAAGTGGAGCTTCGCAACCGAGTTTGCCCAAGTTAGACTATATTGCTCGCC
GGCTAGGAGTTCCAGTTTATGGCCTTATGCCGGATTTTTCAGCTCTTCCTCCTGCTTATTTAGAATTGAAATATCAGATT
TTACGTGAACCAATCTATGGTAAAGAAGAGGAGTACGATAAGAAGGAAGCGTGTTTGGAAGAGATTTATAAAACATACTT
TGATAATCTTCCTAAAGAAGAACAATTAGCATGTGAAGTATTGCAGGCGTGTTTGGATACTTCTAGAACTAGAAGGCCTG
AATATGCAGAGTTAATACTTGAGGAACATATGCCTCAGATCATAGAAAAAGAAGTTTATTCAACAAATGATATGTTGTTG
ATTCGTTTGTTTTTTTATCAAATGCTCATTAGAAAAGATCTTGCCAAATTTATAAATCAAATCGAAGAGCTAATGCTCTT
TCTTTTGGAACAGAAAAAGGTAACTAAATTAGAAAACTTCTTTATAATTAGAGATACTCTTATTTCAGGAATGTGTTGTC
TTGAAAAGGTAGGAGTAACTGATTGTTTTAATGATTATCTATCGTGTTTACAAGAAATTATGGATAAAACTCAAGATTAT
CAAAAGAAACCTCTTGTATTTATGTTTTTGTGGAAGCAAGCATTAAGAGAAGAAAGAGATTTTAGTTTAGCTGAATCATT
TTATCAGTCTTCTAAAACATTTGCGCAGCTAATTGGAGATGAATTTCTAGTAAAGAAATTGACAGAGGAATGGCAAGAGG
ATGTCAAAAAATATTTATAA

Domains

Predicted by InterProScan.

• ComR tetratricopeptide (ComR_TPR) (70-291)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus mutans UA159	37.966	98.662	0.375
comR	Streptococcus pyogenes MGAS8232	36.789	100	0.368
comR	Streptococcus pyogenes MGAS315	36.213	100	0.365
comR	Streptococcus suis P1/7	37.113	97.324	0.361
comR	Streptococcus suis 05ZYH33	37.113	97.324	0.361