Detailed information NTG0585669

Bioinformatically predicted

Overview

• Name: ciaR
• Type: Regulator
• Locus tag: KVP03_RS07845
• Genome accession: NZ_CP077959
• Coordinates: 1649963..1650637 (-)
• Length: 224 a.a.
• NCBI ID: WP_021320708.1
• Uniprot ID: A0AAW3GMV5
• Organism: Streptococcus equi subsp. zooepidemicus strain SEZ_14-145
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1644963..1655637

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KVP03_RS07795 (KVP03_07775)	-	1645057..1645476 (-)	420	WP_111692735.1	hypothetical protein	-
KVP03_RS07800 (KVP03_07780)	-	1645492..1645752 (-)	261	WP_154299136.1	hypothetical protein	-
KVP03_RS07805 (KVP03_07785)	-	1645749..1646126 (-)	378	WP_111692736.1	hypothetical protein	-
KVP03_RS07810 (KVP03_07790)	-	1646297..1646548 (-)	252	WP_111692737.1	hypothetical protein	-
KVP03_RS07815 (KVP03_07795)	-	1646616..1646873 (-)	258	WP_230923019.1	hypothetical protein	-
KVP03_RS07820 (KVP03_07800)	-	1646860..1647150 (-)	291	WP_230923020.1	hypothetical protein	-
KVP03_RS07825 (KVP03_07805)	-	1647160..1647567 (-)	408	WP_014622815.1	hypothetical protein	-
KVP03_RS07830 (KVP03_07810)	-	1647583..1647759 (-)	177	WP_014622814.1	hypothetical protein	-
KVP03_RS07835 (KVP03_07815)	-	1647841..1648275 (-)	435	WP_012678015.1	hypothetical protein	-
KVP03_RS07840 (KVP03_07820)	ciaH	1648660..1649970 (-)	1311	WP_012515549.1	sensor histidine kinase	Regulator
KVP03_RS07845 (KVP03_07825)	ciaR	1649963..1650637 (-)	675	WP_021320708.1	response regulator transcription factor	Regulator
KVP03_RS07850 (KVP03_07830)	-	1651056..1653593 (-)	2538	WP_043052123.1	M1 family metallopeptidase	-
KVP03_RS07855 (KVP03_07835)	phoU	1653828..1654481 (-)	654	WP_012678018.1	phosphate signaling complex protein PhoU	-
KVP03_RS07860 (KVP03_07840)	pstB	1654552..1655310 (-)	759	WP_012678019.1	phosphate ABC transporter ATP-binding protein PstB	-

Sequence

Protein

• Length: 224 a.a.
• Molecular weight: 25569.58 Da
• Isoelectric Point: 4.5644

>NTDB_id=585669 KVP03_RS07845 WP_021320708.1 1649963..1650637(-) (ciaR) [Streptococcus equi subsp. zooepidemicus strain SEZ_14-145]
MIKLLLVEDDLSLSNSIFDFLDDFADVTQVFDGDEGLYEAESGIYDLILLDLMLPEKDGFQVLKALREKDIKIPVLIMTA
KESIDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRVGKFNDKSLKFGNLTVDTTRKEVQVNGQVIELLGKELDLLIY
ILQNQNVILPKSQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTDFVNHLQTLRSVGYILKANE

Nucleotide

• Length: 675 bp

>NTDB_id=585669 KVP03_RS07845 WP_021320708.1 1649963..1650637(-) (ciaR) [Streptococcus equi subsp. zooepidemicus strain SEZ_14-145]
ATGATAAAACTATTATTAGTAGAAGACGATTTAAGCTTATCAAATTCCATCTTTGATTTTTTAGATGACTTTGCTGATGT
GACCCAGGTTTTTGATGGCGACGAAGGACTCTATGAGGCAGAAAGCGGCATTTATGATTTGATTCTGTTAGATTTGATGC
TGCCTGAAAAGGATGGCTTTCAAGTGCTAAAGGCCTTACGTGAAAAAGACATCAAAATTCCCGTCTTGATCATGACTGCC
AAAGAAAGCATTGATGACAAGGGACATGGCTTTGAGCTTGGTGCTGATGACTATTTAACCAAGCCCTTTTACCTAGAGGA
ATTAAAAATGCGGATTCAGGCCTTGCTTAAGCGCGTAGGAAAGTTTAATGATAAGAGCCTTAAATTTGGCAACCTGACTG
TAGATACTACCCGTAAAGAGGTACAGGTCAATGGGCAGGTCATAGAGCTATTAGGCAAGGAGCTTGATTTACTAATCTAT
ATCCTTCAAAATCAAAATGTTATTTTGCCAAAGTCACAAATTTTTGATCGTATCTGGGGCTTTGATAGTGATACCACTAT
CTCTGTTGTAGAGGTCTATGTCTCTAAAATCCGTAAGAAGCTTAAGGGGACAGACTTTGTTAATCATCTTCAAACCTTGA
GAAGTGTAGGATATATCTTAAAAGCTAATGAATAA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (5-112)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (145-220)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaR	Streptococcus mutans UA159	84.615	98.661	0.835
ciaR	Streptococcus pneumoniae Rx1	80.543	98.661	0.795
ciaR	Streptococcus pneumoniae D39	80.543	98.661	0.795
ciaR	Streptococcus pneumoniae R6	80.543	98.661	0.795
ciaR	Streptococcus pneumoniae TIGR4	80.543	98.661	0.795
covR	Lactococcus lactis subsp. lactis strain DGCC12653	38.865	100	0.397