Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC/celB   Type   Machinery gene
Locus tag   I872_RS06795 Genome accession   NC_021175
Coordinates   1369469..1371709 (-) Length   746 a.a.
NCBI ID   WP_015605400.1    Uniprot ID   -
Organism   Streptococcus cristatus AS 1.3089     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1364469..1376709
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I872_RS06775 (I872_06785) tuf 1365399..1366595 (-) 1197 WP_015605396.1 elongation factor Tu -
  I872_RS06780 (I872_06790) - 1366718..1367707 (-) 990 WP_015605397.1 anti sigma factor C-terminal domain-containing protein -
  I872_RS06785 (I872_06795) - 1367694..1368164 (-) 471 WP_172456459.1 RNA polymerase sigma factor -
  I872_RS06790 (I872_06800) - 1368448..1369362 (-) 915 WP_015605399.1 DUF805 domain-containing protein -
  I872_RS06795 (I872_06805) comEC/celB 1369469..1371709 (-) 2241 WP_015605400.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  I872_RS06800 (I872_06810) comEA/celA/cilE 1371690..1372382 (-) 693 WP_015605401.1 helix-hairpin-helix domain-containing protein Machinery gene
  I872_RS06805 (I872_06815) - 1372658..1373398 (-) 741 WP_015605402.1 lysophospholipid acyltransferase family protein -
  I872_RS06810 (I872_06820) - 1373555..1375894 (+) 2340 WP_015605403.1 cation-translocating P-type ATPase -

Sequence

Protein


Download         Length: 746 a.a.        Molecular weight: 84880.74 Da        Isoelectric Point: 7.9934

>NTDB_id=58462 I872_RS06795 WP_015605400.1 1369469..1371709(-) (comEC/celB) [Streptococcus cristatus AS 1.3089]
MSQWINKFPIKPIYFCLLLVLTYFAVYTGSLPVYLGLAALLVRLFWLYSTKNSLLVLMLLSLFAGFFLFRREMANQAFQD
EPKTISAIVMKPDTIKVNGDSLSFRGHSNGRTYQAFYKIQSEQEKQAFQKLSDQLLLEIDGELSLAEDQRNFSGFDYRAY
LKTQGIYRILKINQIKSSQHFSSLNTWDWLSVWRRKALVYIKENFPSPMSHYMTGLLFGDLDTDFAEMNELYSSLGIIHL
FALSGMQVGYFMDGFRRILLKSGLKRETVDWLQSPFSFIYAGLTGFSVSVVRSLVQKLLSQFGVTKLDNFALTIVLLVIF
MPNFLLTTGGVLSCAYAFVISVMDFEQLPPVRKVLAESLTISLGILPILIFYFSEFQPWSILLTFLFSVVFDLFMLPALT
FIFALSPLLKITQVNALFELLEGLIRWTAAISSRPVVFGQPSIWMMLGLLIILSLLYDFRRQKKALILLSLALALLFFLT
KHPLQNEITVIDIGQGDSIFLRDWRGKSVLIDVGGRVEIGKKEAWQKRVSSTNAEKTLIPYLKSRGLSHLDVLVLTHTDT
DHMGDMLEVAKHFSIKEIYVSKGSLTQSDFVEKLERMQTRVHAVEVGDSLPIFDGSLQVLYPEDTGDGSNDDSVVLYGKF
FGTSFLFTGDLEENGEATLMRRFPQLKVDVLKAGHHGSKGSSSPEFLHQLQPQIALISAGKNNRYKHPHQETLDRFENIQ
TQIFRTDEQGAIRFSGWDSWQIETVK

Nucleotide


Download         Length: 2241 bp        

>NTDB_id=58462 I872_RS06795 WP_015605400.1 1369469..1371709(-) (comEC/celB) [Streptococcus cristatus AS 1.3089]
ATGTCACAGTGGATAAATAAATTTCCCATTAAACCAATCTATTTTTGTCTGTTGCTAGTGTTGACCTACTTTGCTGTTTA
CACAGGCAGTCTGCCAGTTTATCTGGGTTTGGCAGCTCTCCTTGTTCGGCTCTTTTGGCTTTATTCGACGAAGAATAGTC
TGCTTGTTTTGATGCTTTTGAGTCTTTTTGCTGGATTTTTCCTATTTCGGAGAGAAATGGCTAATCAAGCCTTTCAAGAT
GAACCGAAAACTATCTCTGCCATTGTGATGAAGCCAGATACAATCAAAGTCAATGGCGACTCGCTTTCTTTTCGCGGTCA
TTCCAATGGTCGAACCTATCAGGCTTTTTATAAAATCCAGTCAGAACAGGAAAAACAAGCTTTTCAAAAGTTGAGTGATC
AACTGCTTTTGGAGATTGATGGAGAGCTTAGTTTAGCAGAAGACCAGCGTAATTTTTCAGGCTTTGACTATCGGGCTTAT
CTGAAAACGCAGGGGATTTACAGGATTTTGAAGATCAATCAAATCAAGTCCAGTCAGCATTTTAGCAGTCTTAATACTTG
GGATTGGTTATCGGTCTGGCGCAGAAAAGCCTTGGTTTATATCAAAGAAAACTTTCCTAGTCCCATGAGCCACTATATGA
CTGGACTCTTGTTTGGTGACTTGGATACAGATTTTGCTGAGATGAATGAACTTTATTCCAGTCTGGGGATTATCCATCTC
TTTGCCCTATCTGGAATGCAGGTCGGCTATTTCATGGATGGTTTTCGCCGGATTCTCCTGAAATCTGGTTTAAAAAGGGA
AACCGTTGATTGGCTTCAGTCGCCCTTTTCCTTCATCTATGCGGGTTTGACGGGCTTTTCAGTATCGGTTGTGAGGAGCT
TAGTGCAAAAGTTGCTCTCGCAGTTCGGTGTGACCAAGCTGGACAACTTTGCTTTAACGATCGTGCTCCTAGTCATTTTC
ATGCCCAATTTTCTCTTGACGACGGGTGGAGTTCTTTCCTGTGCCTATGCTTTTGTCATTTCGGTCATGGATTTTGAGCA
GTTACCTCCCGTACGAAAGGTGCTGGCAGAAAGTCTGACCATTTCACTGGGGATTTTGCCGATTCTGATTTTCTATTTTT
CTGAATTTCAGCCTTGGTCTATTCTGCTGACTTTTCTATTTTCAGTTGTTTTTGATCTTTTTATGCTTCCAGCCCTGACC
TTTATTTTTGCCCTATCGCCTCTTTTGAAAATTACCCAGGTCAATGCCTTGTTTGAACTGCTGGAAGGGCTGATTCGTTG
GACGGCGGCTATTTCCTCACGGCCAGTGGTTTTTGGTCAGCCATCCATCTGGATGATGCTAGGTCTGCTGATCATTCTTA
GCTTGCTTTATGATTTTCGTAGACAGAAGAAAGCCTTAATCTTACTCAGCTTGGCTCTAGCTCTGCTCTTTTTCCTCACA
AAGCATCCCTTGCAAAATGAAATTACCGTCATTGATATTGGGCAGGGAGATAGCATTTTCTTGCGCGATTGGCGGGGGAA
ATCTGTTCTGATTGATGTAGGTGGTCGAGTGGAGATTGGCAAGAAAGAAGCCTGGCAGAAGAGGGTTTCTTCGACAAATG
CAGAAAAGACCTTGATTCCCTATCTGAAAAGTCGGGGACTGAGTCACTTGGATGTGCTGGTTTTGACCCACACGGATACG
GACCATATGGGCGATATGCTGGAAGTAGCCAAGCATTTTTCTATAAAGGAAATTTATGTATCTAAGGGAAGTTTGACTCA
GTCGGATTTTGTGGAGAAACTGGAGCGGATGCAGACGAGAGTCCATGCGGTAGAAGTGGGAGATAGCCTTCCAATTTTTG
ATGGATCTTTGCAGGTTCTCTATCCTGAGGATACAGGCGACGGTAGCAATGATGACTCTGTCGTTTTGTACGGGAAGTTT
TTTGGAACTAGCTTTTTGTTTACGGGAGACTTAGAGGAGAATGGCGAAGCTACCTTGATGCGGCGTTTTCCGCAACTCAA
GGTGGATGTTTTAAAAGCAGGCCACCACGGTTCTAAGGGCTCCTCTAGCCCAGAATTTTTACATCAGCTTCAGCCCCAAA
TTGCCCTCATTTCTGCGGGTAAGAATAACCGTTACAAGCATCCTCATCAGGAAACTTTAGACAGATTTGAGAACATTCAG
ACACAGATTTTTCGTACAGATGAGCAGGGAGCCATTCGCTTTAGTGGCTGGGATTCTTGGCAGATTGAGACTGTAAAGTA
A

Domains

Predicted by InterproScan.

Domain of unknown function (DUF4131) (DUF4131)

(34-175)

Metallo-beta-lactamase superfamily (Lactamase_B)

(494-700)

Competence protein (Competence)

(216-460)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC/celB Streptococcus mitis NCTC 12261

57.239

100

0.572
  comEC/celB Streptococcus mitis SK321

57.162

100

0.572
  comEC/celB Streptococcus pneumoniae TIGR4

56.493

100

0.566
  comEC/celB Streptococcus pneumoniae Rx1

55.689

100

0.558
  comEC/celB Streptococcus pneumoniae D39

55.689

100

0.558
  comEC/celB Streptococcus pneumoniae R6

55.689

100

0.558
  comEC Lactococcus lactis subsp. cremoris KW2

47.651

99.866

0.476

Multiple sequence alignment