Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   I872_RS06070 Genome accession   NC_021175
Coordinates   1214203..1215504 (-) Length   433 a.a.
NCBI ID   WP_041826810.1    Uniprot ID   -
Organism   Streptococcus cristatus AS 1.3089     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1209203..1220504
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I872_RS06055 (I872_06040) - 1209643..1212765 (-) 3123 WP_015605255.1 DEAD/DEAH box helicase -
  I872_RS06060 (I872_06045) hpf 1212917..1213459 (-) 543 WP_015605256.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  I872_RS06065 (I872_06050) comFC/cflB 1213541..1214206 (-) 666 WP_015605257.1 ComF family protein Machinery gene
  I872_RS06070 (I872_06055) comFA/cflA 1214203..1215504 (-) 1302 WP_041826810.1 DEAD/DEAH box helicase Machinery gene
  I872_RS06075 (I872_06060) - 1215561..1216196 (+) 636 WP_015605259.1 YigZ family protein -
  I872_RS06080 (I872_06065) cysK 1216313..1217242 (+) 930 WP_015605260.1 cysteine synthase A -
  I872_RS06085 (I872_06070) - 1217293..1217655 (-) 363 WP_015605261.1 S1 RNA-binding domain-containing protein -
  I872_RS06090 (I872_06075) - 1217655..1219055 (-) 1401 WP_015605262.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  I872_RS06095 (I872_06080) - 1219093..1219725 (-) 633 WP_015605263.1 response regulator transcription factor -

Sequence

Protein


Download         Length: 433 a.a.        Molecular weight: 49917.70 Da        Isoelectric Point: 8.6806

>NTDB_id=58453 I872_RS06070 WP_041826810.1 1214203..1215504(-) (comFA/cflA) [Streptococcus cristatus AS 1.3089]
MLERKDCLGRIFTKDQLSPELRSQAQQMPSMREERRRLFCSRCGSQVDKENYQLPVNAYYCRECLILGRVRSDQELYYFP
QEDFPENQVLKWQGKLTAFQEKVSQGLLESVVQKQNSLVHAVTGAGKTEMIYQVIAEVVDRGGAVCLASPRIDVCLELYR
RLKLDFACPISLLHGESEPYFRSPLVIATTHQLLKFYRAFDLLIVDEVDAFPYVDNPVLYHAVDQSVKEEGTTIFLTATS
TDELDKKVQKGELKRLSLPRRFHGNPLIVPQKVWLADFQKYLAKKKLPPKLRKYIERQRKTGFPLLIFASEIKRGQEFAQ
VLEENFPAERVGFVASTTENRLEIVEEFRKREITILVTTTILERGVTFPCVDVFVLEAHHRLFSRSALVQISGRVGRSMD
RPTGDLFFFHDGTTRSIEKAIREIKLMNKEAGL

Nucleotide


Download         Length: 1302 bp        

>NTDB_id=58453 I872_RS06070 WP_041826810.1 1214203..1215504(-) (comFA/cflA) [Streptococcus cristatus AS 1.3089]
ATGTTAGAAAGAAAAGATTGTTTAGGTAGGATATTTACAAAGGATCAGCTAAGTCCTGAGCTGCGCTCGCAGGCCCAGCA
GATGCCCAGTATGCGAGAGGAAAGGCGGAGATTGTTTTGCAGCCGCTGTGGCTCTCAAGTGGACAAGGAGAACTACCAAC
TACCTGTCAACGCCTATTATTGCAGGGAATGTCTGATATTGGGGCGAGTTCGGAGTGATCAAGAACTTTATTATTTTCCG
CAGGAAGACTTTCCAGAAAATCAGGTACTCAAGTGGCAGGGGAAATTGACAGCCTTTCAAGAGAAAGTTTCTCAGGGACT
GTTAGAGTCAGTCGTTCAAAAGCAGAATAGCTTGGTTCATGCGGTGACTGGGGCAGGCAAAACGGAGATGATTTATCAGG
TGATTGCAGAGGTGGTTGATCGCGGAGGTGCCGTTTGCCTGGCCAGCCCGCGGATTGATGTCTGTTTGGAGCTTTATCGT
CGCCTTAAGCTAGATTTTGCTTGCCCGATTTCGCTTTTGCATGGCGAATCCGAGCCCTATTTTCGCAGTCCCTTGGTCAT
CGCCACCACCCATCAGCTTCTTAAATTTTATCGAGCCTTTGATTTGCTGATTGTGGACGAGGTGGATGCCTTTCCTTATG
TGGACAATCCCGTGCTCTACCATGCCGTAGATCAGTCGGTCAAGGAGGAGGGAACGACAATTTTCTTAACTGCCACTTCG
ACGGATGAGTTGGATAAAAAAGTCCAAAAAGGAGAATTAAAACGACTCAGCCTTCCTCGCCGCTTCCATGGCAATCCTTT
GATTGTGCCCCAAAAAGTTTGGCTGGCAGATTTTCAAAAATATCTAGCGAAAAAGAAATTGCCACCTAAACTGAGAAAAT
ATATCGAGAGACAGAGAAAAACAGGCTTTCCTTTGCTGATCTTTGCCTCAGAAATCAAGAGAGGTCAAGAATTTGCGCAA
GTTTTAGAGGAGAATTTTCCAGCGGAAAGAGTCGGTTTTGTAGCTTCAACAACTGAAAATCGTTTAGAAATCGTTGAAGA
GTTTCGCAAGCGAGAAATTACCATTTTGGTCACGACGACCATCTTAGAGCGTGGTGTGACCTTTCCCTGTGTAGATGTCT
TTGTTCTGGAGGCCCACCATCGTCTCTTTAGCCGTAGCGCCTTGGTGCAAATTTCTGGACGGGTGGGACGTAGTATGGAT
AGACCGACGGGAGATTTATTCTTCTTTCACGACGGCACTACACGTTCAATCGAAAAAGCGATTCGTGAAATCAAACTGAT
GAACAAGGAGGCTGGCCTATGA

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(297-397)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus mitis NCTC 12261

71.831

98.383

0.707
  comFA/cflA Streptococcus pneumoniae D39

71.028

98.845

0.702
  comFA/cflA Streptococcus pneumoniae R6

71.028

98.845

0.702
  comFA/cflA Streptococcus pneumoniae TIGR4

71.028

98.845

0.702
  comFA/cflA Streptococcus pneumoniae Rx1

71.028

98.845

0.702
  comFA/cflA Streptococcus mitis SK321

70.892

98.383

0.697
  comFA Lactococcus lactis subsp. cremoris KW2

54.68

93.764

0.513
  comFA Latilactobacillus sakei subsp. sakei 23K

41.628

99.307

0.413
  comFA Bacillus subtilis subsp. subtilis str. 168

39.659

94.919

0.376

Multiple sequence alignment