Detailed information NTG0058336

Bioinformatically predicted

Overview

• Name: ruvA
• Type: Machinery gene
• Locus tag: EP178_RS10275
• Genome accession: NZ_AP018377
• Coordinates: 1749801..1750385 (+)
• Length: 194 a.a.
• NCBI ID: WP_003689924.1
• Uniprot ID: Q5F636
• Organism: Neisseria gonorrhoeae strain FC428
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1744801..1755385

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EP178_RS13805	-	1745540..1745650 (+)	111	Protein_1762	IS5/IS1182 family transposase	-
EP178_RS10240 (NgFC428_01799)	-	1745731..1746519 (-)	789	WP_003689910.1	class I SAM-dependent methyltransferase	-
EP178_RS10245 (NgFC428_01800)	bioH	1746516..1747265 (-)	750	WP_010360850.1	pimeloyl-ACP methyl ester esterase BioH	-
EP178_RS10250 (NgFC428_01801)	-	1747264..1747989 (+)	726	WP_003696136.1	ComF family protein	-
EP178_RS10255 (NgFC428_01802)	trmL	1748054..1748518 (+)	465	WP_003689916.1	tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL	-
EP178_RS10265 (NgFC428_01803)	-	1748646..1749332 (+)	687	WP_003696139.1	septal ring lytic transglycosylase RlpA family protein	-
EP178_RS10270 (NgFC428_01804)	-	1749393..1749719 (+)	327	WP_003689921.1	PepSY domain-containing protein	-
EP178_RS10275 (NgFC428_01805)	ruvA	1749801..1750385 (+)	585	WP_003689924.1	Holliday junction branch migration protein RuvA	Machinery gene
EP178_RS10280 (NgFC428_01806)	-	1750385..1750522 (+)	138	WP_003689926.1	hypothetical protein	-
EP178_RS10285 (NgFC428_01807)	-	1750548..1752404 (+)	1857	WP_103195239.1	ABC transporter ATP-binding protein	-
EP178_RS10290 (NgFC428_01808)	rsgA	1752409..1753332 (+)	924	WP_003689928.1	ribosome small subunit-dependent GTPase A	-
EP178_RS10295 (NgFC428_01809)	-	1753445..1753669 (+)	225	WP_003689929.1	exodeoxyribonuclease VII small subunit	-
EP178_RS10300 (NgFC428_01810)	-	1753653..1754549 (+)	897	WP_050157366.1	polyprenyl synthetase family protein	-
EP178_RS10305 (NgFC428_01811)	-	1754666..1754965 (-)	300	WP_010359269.1	DUF2818 family protein	-

Sequence

Protein

• Length: 194 a.a.
• Molecular weight: 20729.99 Da
• Isoelectric Point: 6.4967

>NTDB_id=58336 EP178_RS10275 WP_003689924.1 1749801..1750385(+) (ruvA) [Neisseria gonorrhoeae strain FC428]
MISRLTGKLVEKNPPQIVIDVNGVGYEADVSMQTFYNLPPVGESVQLFTQLIIREDAHLLFGFATAEERKTFRQLIKVGG
IGAKTALGILSAMTADELARAVAEEDVKRLSSAPGIGKKTAERMVLELRGKLVAHTVTDGLFAASPAADETEDIVSTLLA
LGYNEREAKAAVKGVPKGTDVGEGVRLALKNLLK

Nucleotide

• Length: 585 bp

>NTDB_id=58336 EP178_RS10275 WP_003689924.1 1749801..1750385(+) (ruvA) [Neisseria gonorrhoeae strain FC428]
ATGATCAGCAGACTGACCGGCAAACTGGTTGAAAAAAACCCTCCGCAAATCGTCATCGATGTCAACGGTGTCGGTTATGA
AGCCGACGTATCGATGCAGACCTTCTACAACCTGCCGCCCGTGGGTGAAAGCGTACAACTGTTTACCCAGCTTATCATTC
GGGAAGACGCACATCTTTTATTTGGTTTTGCCACTGCGGAAGAACGCAAGACCTTCCGCCAACTGATTAAGGTCGGCGGC
ATCGGCGCGAAAACGGCTTTGGGCATTTTGTCGGCGATGACGGCAGACGAGCTGGCGCGGGCGGTTGCAGAAGAAGATGT
CAAACGCCTCTCCTCCGCTCCGGGAATCGGCAAAAAAACCGCCGAACGTATGGTCTTGGAACTGCGCGGCAAGCTGGTCG
CGCATACGGTAACGGACGGGCTGTTTGCCGCCTCACCCGCCGCCGACGAAACGGAAGACATCGTCAGCACGCTGCTTGCG
CTGGGTTACAACGAACGCGAGGCAAAAGCGGCGGTCAAAGGCGTTCCGAAGGGGACGGACGTGGGCGAAGGCGTGCGCCT
TGCCCTGAAAAACCTGCTGAAATAA

Domains

Predicted by InterProScan.

• Helix-hairpin-helix domain (HHH_5) (72-129)

• RuvA N terminal domain (RuvA_N) (1-62)

• RuvA, C-terminal domain (RuvA_C) (150-192)

3D structure

• AlphaFold DB: Q5F636

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ruvA	Streptococcus pneumoniae R6	38	100	0.392
ruvA	Streptococcus pneumoniae D39	38	100	0.392
ruvA	Streptococcus pneumoniae TIGR4	37.5	100	0.387
ruvA	Bacillus subtilis subsp. subtilis str. 168	34.951	100	0.371