Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   MHH_RS15760 Genome accession   NC_021082
Coordinates   358468..359616 (-) Length   382 a.a.
NCBI ID   WP_006248764.1    Uniprot ID   A0A547ELA4
Organism   Mannheimia haemolytica M42548     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 353468..364616
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MHH_RS15730 (MHH_c03860) rplK 353736..354164 (-) 429 WP_006248758.1 50S ribosomal protein L11 -
  MHH_RS15735 (MHH_c03880) nusG 354397..354960 (-) 564 WP_006248760.1 transcription termination/antitermination protein NusG -
  MHH_RS15740 (MHH_c03890) secE 354962..355375 (-) 414 WP_006248761.1 preprotein translocase subunit SecE -
  MHH_RS15745 (MHH_c03900) - 355488..356510 (-) 1023 WP_006248762.1 LacI family DNA-binding transcriptional regulator -
  MHH_RS15750 (MHH_c03910) - 356741..357010 (+) 270 WP_006248763.1 PTS sugar transporter subunit IIB -
  MHH_RS28210 - 357023..358373 (+) 1351 Protein_352 PTS ascorbate transporter subunit IIC -
  MHH_RS15760 (MHH_c03940) dprA 358468..359616 (-) 1149 WP_006248764.1 DNA-processing protein DprA Machinery gene
  MHH_RS15765 (MHH_c03950) def 359705..360217 (+) 513 WP_006248765.1 peptide deformylase -
  MHH_RS15770 (MHH_c03960) rfaD 360311..361237 (+) 927 WP_006248766.1 ADP-glyceromanno-heptose 6-epimerase -
  MHH_RS15775 (MHH_c03970) fabA 361305..361835 (-) 531 WP_006248767.1 bifunctional 3-hydroxydecanoyl-ACP dehydratase/trans-2-decenoyl-ACP isomerase -
  MHH_RS15780 (MHH_c03980) - 361948..363585 (-) 1638 WP_006248768.1 AAA family ATPase -
  MHH_RS15785 (MHH_c03990) matP 363678..364124 (+) 447 WP_006248769.1 macrodomain Ter protein MatP -

Sequence

Protein


Download         Length: 382 a.a.        Molecular weight: 42497.83 Da        Isoelectric Point: 5.2272

>NTDB_id=58282 MHH_RS15760 WP_006248764.1 358468..359616(-) (dprA) [Mannheimia haemolytica M42548]
MAYHYDLLRLLQVPQMGAQRIGRLLAELNFAEFCHYDKLQLKQIGWNEKQIQRWFNPDQKWIDQAMTWSELPNQQIVTLF
DENYPFLLKQISTAPPLIYVKGNVESLSLPQIAIVGSRDYSHYGEYWAGQFAAELARHNIIITSGLAIGIDGFAHQKIVM
EQGITIAVLGSGLNQVYPARHKKLAEQIVDLGGALVSEFSPNQPPVAENFPRRNRIISGLSLGTLVIEATLNSGSLITAR
YALEQGREVFALPNAVQNPYAQGCHKLIKEGALLVEGVEDILEVVASQYQPQQIPLFDESKPTVSTSLQAVKNSEKFAKN
LPSLTACQQQIYQHISLEPMAIDDLAKVTELTIEILLVELLGLELAGVIKQVSGGYVMDNGY

Nucleotide


Download         Length: 1149 bp        

>NTDB_id=58282 MHH_RS15760 WP_006248764.1 358468..359616(-) (dprA) [Mannheimia haemolytica M42548]
ATGGCATATCACTACGATTTATTACGATTATTACAAGTGCCGCAAATGGGGGCTCAACGTATAGGGCGATTATTGGCGGA
ACTCAATTTTGCTGAATTTTGCCACTATGACAAACTTCAACTCAAACAAATAGGTTGGAATGAAAAGCAAATTCAACGTT
GGTTTAATCCTGATCAAAAGTGGATTGATCAGGCGATGACTTGGTCAGAATTGCCAAATCAGCAAATTGTGACACTCTTT
GATGAAAATTATCCGTTTCTCTTAAAACAAATTTCGACTGCGCCACCGTTAATTTATGTAAAGGGAAATGTGGAAAGCCT
TTCTCTGCCACAAATTGCGATTGTTGGCAGCCGAGACTATTCTCATTATGGTGAATATTGGGCTGGGCAATTTGCTGCCG
AATTAGCTCGCCATAATATTATCATTACCAGCGGTTTAGCCATTGGTATTGACGGTTTTGCCCATCAAAAAATCGTTATG
GAACAAGGCATAACGATTGCCGTGTTAGGGAGTGGATTAAATCAAGTCTATCCTGCTCGCCATAAAAAATTAGCCGAACA
AATTGTTGATTTAGGTGGTGCATTGGTGTCGGAGTTCTCGCCTAATCAGCCGCCGGTGGCAGAAAATTTTCCTCGTCGTA
ATCGAATTATTAGTGGCTTATCGCTCGGCACTTTAGTTATTGAAGCAACGCTTAATAGTGGTTCACTGATTACCGCTCGT
TATGCCCTTGAACAAGGTAGGGAAGTGTTTGCGTTACCGAATGCGGTACAAAACCCTTACGCACAAGGTTGCCACAAGCT
AATTAAAGAAGGGGCATTGCTCGTGGAAGGTGTGGAAGATATTTTAGAGGTGGTCGCCTCGCAATATCAACCTCAGCAAA
TCCCTTTGTTTGATGAGTCTAAGCCAACAGTAAGCACATCTTTACAAGCGGTCAAAAACAGCGAAAAATTCGCAAAAAAT
CTGCCAAGTCTGACCGCTTGCCAGCAGCAAATTTATCAGCATATCAGCTTAGAGCCGATGGCAATTGATGATTTAGCCAA
AGTTACGGAGTTGACGATTGAAATATTGCTGGTTGAATTACTGGGTCTGGAATTAGCCGGTGTGATTAAACAAGTGAGTG
GGGGGTATGTGATGGATAATGGGTATTGA

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(73-275)

DprA winged helix domain (DprA_WH)

(317-375)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A547ELA4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Glaesserella parasuis strain SC1401

73.615

99.215

0.73
  dprA Haemophilus influenzae Rd KW20

51.304

90.314

0.463
  dprA Vibrio campbellii strain DS40M4

44.744

97.12

0.435
  dprA Vibrio cholerae strain A1552

42.588

97.12

0.414
  dprA Legionella pneumophila strain ERS1305867

40.29

90.314

0.364

Multiple sequence alignment