Detailed information NTG0580403

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: I6L86_RS07615
• Genome accession: NZ_CP077259
• Coordinates: 1570253..1571206 (+)
• Length: 317 a.a.
• NCBI ID: WP_000495920.1
• Uniprot ID: A0A081SCJ1
• Organism: Streptococcus mitis strain FDAARGOS 1456
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1565253..1576206

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6L86_RS07590 (I6L86_07590)	rpmG	1565997..1566146 (+)	150	WP_001809104.1	50S ribosomal protein L33	-
I6L86_RS07595 (I6L86_07595)	secG	1566186..1566419 (+)	234	WP_000282517.1	preprotein translocase subunit SecG	-
I6L86_RS07600 (I6L86_07600)	rnr	1566521..1568875 (+)	2355	WP_000654876.1	ribonuclease R	-
I6L86_RS07605 (I6L86_07605)	smpB	1568838..1569305 (+)	468	WP_001051750.1	SsrA-binding protein SmpB	-
I6L86_RS07610 (I6L86_07610)	tehB	1569320..1570180 (+)	861	WP_000413782.1	SAM-dependent methyltransferase TehB	-
I6L86_RS07615 (I6L86_07615)	coiA	1570253..1571206 (+)	954	WP_000495920.1	competence protein CoiA	Machinery gene
I6L86_RS07620 (I6L86_07620)	pepF	1571225..1573027 (+)	1803	WP_000244089.1	oligoendopeptidase F	Regulator
I6L86_RS07625 (I6L86_07625)	-	1573029..1573742 (+)	714	WP_004239376.1	O-methyltransferase	-
I6L86_RS07630 (I6L86_07630)	prsA	1573809..1574747 (+)	939	WP_000727954.1	peptidylprolyl isomerase PrsA	-
I6L86_RS07635 (I6L86_07635)	ftsW	1574908..1576131 (+)	1224	WP_000703370.1	cell division peptidoglycan polymerase FtsW	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 38161.88 Da
• Isoelectric Point: 8.3929

>NTDB_id=580403 I6L86_RS07615 WP_000495920.1 1570253..1571206(+) (coiA) [Streptococcus mitis strain FDAARGOS 1456]
MFVARDSRGELVNVLEDKLEKQAYTCPACGGQLRLRQGPSVRIHFAHKTLKDCDFSSENESPEHLENKEVLYHWLKKEAE
VQLEYLLPELKQIADVFVNGNLALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGKKLWLKERLTRLQQGFLYFSQNMGF
YVWELDSEKQVLRLKYLIHQDLRGKLHYQIKEFPYGHGSLLEILRFPYKKQKISHFTVSQDKDICRYIRQQLYYQNPIWM
KEQAEAYKKGENLLTYGLKEWYPQIRPLVGNFCQIEQDLIRYYLYFQTYYQENPQNDWQMLYPPAFYQQYFLKNMVE

Nucleotide

• Length: 954 bp

>NTDB_id=580403 I6L86_RS07615 WP_000495920.1 1570253..1571206(+) (coiA) [Streptococcus mitis strain FDAARGOS 1456]
ATGTTTGTTGCGAGAGATTCTAGGGGAGAATTGGTAAATGTGTTAGAGGATAAGCTTGAGAAGCAAGCATACACCTGCCC
AGCTTGTGGAGGTCAGCTCCGTTTGCGTCAAGGACCAAGTGTCCGGATCCATTTTGCCCACAAAACCTTAAAAGACTGTG
ATTTTTCCTCTGAAAATGAAAGTCCAGAACATCTGGAAAATAAGGAAGTCCTTTATCACTGGTTGAAAAAAGAGGCCGAG
GTGCAATTAGAATACCTGCTTCCAGAGCTTAAACAGATTGCGGATGTATTTGTAAATGGCAATCTAGCTTTAGAGGTTCA
ATGTAGTCCCTTGCCTCAAAAAGTTCTTAAAGAGCGTAGCGAGGGCTATCGTAGTCAGGGTTACCAAGTACTGTGGTTGC
TGGGAAAAAAACTGTGGCTCAAGGAGCGTTTGACTCGTCTACAACAAGGTTTTCTCTATTTCAGTCAAAACATGGGCTTT
TATGTTTGGGAATTAGACAGTGAAAAACAAGTTTTAAGACTCAAATACCTGATTCACCAAGATCTCCGAGGTAAACTCCA
TTATCAGATTAAGGAATTTCCCTATGGTCACGGTAGTTTACTGGAGATATTACGTTTTCCCTATAAGAAACAAAAAATAT
CTCATTTTACAGTTTCTCAGGACAAGGACATCTGTCGTTATATCCGGCAACAACTGTACTATCAAAATCCCATTTGGATG
AAAGAACAAGCAGAAGCCTATAAAAAGGGAGAAAATCTCCTGACTTATGGGCTAAAAGAATGGTATCCACAAATTCGACC
ACTAGTAGGTAATTTTTGCCAAATTGAGCAAGATTTGATTCGCTATTATCTGTATTTTCAAACCTATTATCAAGAAAATC
CTCAAAATGATTGGCAAATGCTCTATCCACCAGCCTTTTATCAGCAATATTTCTTAAAAAATATGGTAGAATAG

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (13-256)

3D structure

• AlphaFold DB: A0A081SCJ1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus mitis NCTC 12261	100	100	1
coiA	Streptococcus pneumoniae TIGR4	89.274	100	0.893
coiA	Streptococcus pneumoniae Rx1	89.274	100	0.893
coiA	Streptococcus pneumoniae D39	89.274	100	0.893
coiA	Streptococcus pneumoniae R6	89.274	100	0.893
coiA	Lactococcus lactis subsp. cremoris KW2	44.099	100	0.448