Detailed information NTG0580390

Bioinformatically predicted

Overview

• Name: cclA/cilC
• Type: Machinery gene
• Locus tag: I6L86_RS05630
• Genome accession: NZ_CP077259
• Coordinates: 1174120..1174779 (-)
• Length: 219 a.a.
• NCBI ID: WP_000608383.1
• Uniprot ID: A0AAX2L6K8
• Organism: Streptococcus mitis strain FDAARGOS 1456
• Function: processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1169120..1179779

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6L86_RS05600 (I6L86_05600)	-	1169241..1169807 (+)	567	WP_000601911.1	aminodeoxychorismate/anthranilate synthase component II	-
I6L86_RS05605 (I6L86_05605)	trpD	1169818..1170822 (+)	1005	WP_000658712.1	anthranilate phosphoribosyltransferase	-
I6L86_RS05610 (I6L86_05610)	trpC	1170819..1171592 (+)	774	WP_000076529.1	indole-3-glycerol phosphate synthase TrpC	-
I6L86_RS05615 (I6L86_05615)	-	1171579..1172178 (+)	600	WP_000169924.1	phosphoribosylanthranilate isomerase	-
I6L86_RS05620 (I6L86_05620)	trpB	1172156..1173379 (+)	1224	WP_000331264.1	tryptophan synthase subunit beta	-
I6L86_RS05625 (I6L86_05625)	trpA	1173372..1174148 (+)	777	WP_001127014.1	tryptophan synthase subunit alpha	-
I6L86_RS05630 (I6L86_05630)	cclA/cilC	1174120..1174779 (-)	660	WP_000608383.1	prepilin peptidase	Machinery gene
I6L86_RS05635 (I6L86_05635)	-	1174849..1175304 (+)	456	WP_000155436.1	GNAT family N-acetyltransferase	-
I6L86_RS09140	-	1175340..1175614 (+)	275	Protein_1060	transposase	-
I6L86_RS05640 (I6L86_05640)	-	1175724..1175927 (-)	204	WP_000109960.1	CsbD family protein	-
I6L86_RS05645 (I6L86_05645)	-	1175958..1176566 (-)	609	WP_000064112.1	Asp23/Gls24 family envelope stress response protein	-
I6L86_RS05650 (I6L86_05650)	-	1176604..1176774 (-)	171	WP_000455069.1	DUF2273 domain-containing protein	-
I6L86_RS05655 (I6L86_05655)	amaP	1176786..1177358 (-)	573	WP_000047598.1	alkaline shock response membrane anchor protein AmaP	-
I6L86_RS05660 (I6L86_05660)	-	1177435..1177670 (-)	236	Protein_1065	GlsB/YeaQ/YmgE family stress response membrane protein	-
I6L86_RS05665 (I6L86_05665)	-	1178047..1178912 (+)	866	Protein_1066	helix-turn-helix domain-containing protein	-

Sequence

Protein

• Length: 219 a.a.
• Molecular weight: 24965.33 Da
• Isoelectric Point: 8.1626

>NTDB_id=580390 I6L86_RS05630 WP_000608383.1 1174120..1174779(-) (cclA/cilC) [Streptococcus mitis strain FDAARGOS 1456]
MINIYFFLVGSILASFLGLVIDRFPEQSIIQPASHCDSCHTPLRPLDLIPILSQVFNRFRCRYCKVRYPVWYAFFELGLG
LLFLAWSLGWLSLGQVILITAGLTLGIYDFRHQEYPLLVWMTFHIILMAFCGWSLIMLFFLVLGIIAHFIDIRMGAGDFL
FLASCSIVFSVTELLILIQFASAMGILAFLLQKKKERLPFVPFLLLAACVIIFGKLLLV

Nucleotide

• Length: 660 bp

>NTDB_id=580390 I6L86_RS05630 WP_000608383.1 1174120..1174779(-) (cclA/cilC) [Streptococcus mitis strain FDAARGOS 1456]
ATGATTAATATTTATTTTTTTCTTGTCGGGAGCATTCTCGCTTCCTTTCTTGGTTTGGTTATTGACCGTTTCCCAGAGCA
ATCCATTATCCAACCTGCTAGTCACTGCGATTCCTGTCATACTCCCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCGC
AGGTCTTCAATCGCTTTCGCTGTCGCTACTGCAAGGTTCGCTATCCTGTCTGGTATGCCTTCTTTGAACTAGGCTTAGGA
CTCCTCTTTCTAGCTTGGTCTTTGGGCTGGCTTTCCTTGGGTCAAGTCATCCTGATAACTGCCGGTTTGACCTTGGGCAT
CTACGACTTTCGCCATCAGGAATATCCCTTACTAGTCTGGATGACTTTTCATATAATCCTCATGGCTTTCTGTGGTTGGA
GTCTGATTATGCTCTTCTTTCTTGTTCTAGGAATAATAGCCCATTTTATCGATATCCGTATGGGAGCAGGGGATTTTCTC
TTTTTAGCTTCTTGTTCTATCGTCTTTAGCGTAACGGAGTTACTGATCTTGATTCAATTTGCTTCTGCGATGGGAATTCT
AGCCTTTCTCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTACCTTTCCTCTTACTTGCTGCTTGTGTGATTATTTTTG
GTAAGCTACTGCTTGTCTGA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (8-86)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cclA/cilC	Streptococcus mitis NCTC 12261	100	100	1
cclA/cilC	Streptococcus mitis SK321	88.128	100	0.881
cclA/cilC	Streptococcus pneumoniae Rx1	87.671	100	0.877
cclA/cilC	Streptococcus pneumoniae D39	87.671	100	0.877
cclA/cilC	Streptococcus pneumoniae R6	87.671	100	0.877
cclA/cilC	Streptococcus pneumoniae TIGR4	87.215	100	0.872