Detailed information NTG0580268

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: I6L85_RS02975
• Genome accession: NZ_CP077248
• Coordinates: 587224..589464 (+)
• Length: 746 a.a.
• NCBI ID: WP_111723981.1
• Uniprot ID: -
• Organism: Streptococcus gordonii strain FDAARGOS 1455
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 582224..594464

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6L85_RS02955 (I6L85_02955)	-	582673..585042 (-)	2370	WP_111723984.1	cation-translocating P-type ATPase	-
I6L85_RS02960 (I6L85_02960)	-	585172..585912 (+)	741	WP_041789898.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
I6L85_RS02965 (I6L85_02965)	-	585951..586478 (+)	528	WP_111723983.1	HXXEE domain-containing protein	-
I6L85_RS02970 (I6L85_02970)	comEA/celA/cilE	586575..587240 (+)	666	WP_111723982.1	helix-hairpin-helix domain-containing protein	Machinery gene
I6L85_RS02975 (I6L85_02975)	comEC/celB	587224..589464 (+)	2241	WP_111723981.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
I6L85_RS02980 (I6L85_02980)	holA	589555..590592 (+)	1038	WP_111723980.1	DNA polymerase III subunit delta	-
I6L85_RS02985 (I6L85_02985)	-	590665..591270 (+)	606	WP_045773124.1	superoxide dismutase	-
I6L85_RS02990 (I6L85_02990)	-	591382..592455 (+)	1074	WP_111723979.1	serine hydrolase	-
I6L85_RS02995 (I6L85_02995)	-	592661..593449 (+)	789	WP_111723978.1	YhfC family intramembrane metalloprotease	-
I6L85_RS03000 (I6L85_03000)	-	593427..593711 (+)	285	WP_111723977.1	autorepressor SdpR family transcription factor	-
I6L85_RS03005 (I6L85_03005)	-	593698..594195 (+)	498	WP_111724306.1	DUF1648 domain-containing protein	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 85516.43 Da
• Isoelectric Point: 9.8787

>NTDB_id=580268 I6L85_RS02975 WP_111723981.1 587224..589464(+) (comEC/celB) [Streptococcus gordonii strain FDAARGOS 1455]
MSQWIKKLPLSPIYLCFLLVWLYFAIYSGEKLAYLGVFLLIARLIWHYPRKKWLPTVAILIAFSIFFYARRELAERTFQS
QPAPARQVLVLPDTVKVNGDSLFFRGRIDGRLYQLYYKLASPREKKSFQKLADLVTLEIEGEFNLAEGRRNFSGFDYQAY
LKSQGIYRTVKISRIMSSHSSQSINPFDWLSVWRRKALVFIKSTFPSPMSHYMTGLLFGDLDIEFAEMNDLYSSLGIIHL
FALSGMQVGFFMDAFRKILLRIGLRMETVDWLQFPLSFIYAGLTGFSVSVVRSLVQKLLSQFGVRRLDNFAMAMMALMFL
MPSFLLTTGGVLSCAYAFIITMLDFEDFSGFRKAVLESLSISLGILPILIHYFAEFQPWSILLTFLFSIVFDTFMLPLLS
LIFLISPLFAFTQVNVFFQWLEMVIRWVASLSTRPIILGQPNLPLLIILLLVLALLYDFRKQKKIRAGLSLLAILLFFLS
KYPLQNEITVVDIGQGDSIFLRDVRGRTIVIDTGGRVEIGKKEAWQERVRKSNAETTLIPYLKSRGVDRLDKLVLTHTDT
DHMGDMLELAKHFSIREIYVSKGSMTQVDFVDKLKKMKAKVHVVEVGDRLPIFDSALEVLYPLGQGDGGNDDSIVLYGEF
FRTKFLFTGDLEAPGEGQMVTAYPDLRVDVLKAGHHGSKGSSSPEFLEHIKPKLALISAGKNNRYQHPHKETLDRFEKIQ
TKIFRTDEQGAIRFKGWNSWQIETVR

Nucleotide

• Length: 2241 bp

>NTDB_id=580268 I6L85_RS02975 WP_111723981.1 587224..589464(+) (comEC/celB) [Streptococcus gordonii strain FDAARGOS 1455]
ATGTCACAGTGGATTAAAAAACTTCCCCTTTCACCAATCTATTTGTGCTTTCTTTTGGTTTGGCTCTATTTCGCTATTTA
TAGTGGGGAAAAGCTCGCTTATCTGGGAGTTTTTCTGCTTATAGCTCGACTAATCTGGCATTATCCAAGAAAGAAATGGT
TGCCAACTGTAGCTATCCTAATTGCTTTTTCTATCTTTTTTTATGCTAGACGAGAGTTGGCGGAGCGAACCTTTCAGTCT
CAACCGGCTCCAGCAAGACAAGTTCTTGTTTTACCAGATACGGTTAAAGTGAATGGAGATTCCCTGTTTTTCCGTGGTAG
AATAGACGGAAGACTTTATCAGCTCTACTACAAATTAGCAAGTCCAAGAGAGAAAAAATCATTTCAAAAACTAGCAGACT
TGGTCACTTTAGAAATAGAAGGAGAGTTTAATCTAGCAGAAGGTCGGCGAAATTTTTCTGGTTTTGACTATCAGGCTTAT
TTAAAAAGCCAGGGAATTTATCGGACAGTTAAGATCAGTAGGATTATGTCCAGTCACTCTAGTCAATCTATCAATCCATT
TGATTGGCTGTCTGTTTGGCGTAGGAAGGCTTTGGTTTTCATTAAGTCTACTTTTCCAAGCCCGATGAGTCACTACATGA
CAGGACTTTTGTTTGGAGATTTAGATATTGAATTTGCAGAGATGAATGACTTGTACTCAAGTTTAGGAATTATCCATCTT
TTTGCTTTATCAGGAATGCAGGTTGGCTTTTTTATGGATGCCTTTCGGAAAATTCTTCTGCGCATAGGCTTAAGGATGGA
AACGGTAGATTGGTTGCAATTCCCGTTGTCCTTTATTTATGCAGGTTTGACTGGATTTTCTGTGTCAGTAGTGAGAAGTT
TAGTGCAAAAATTATTGTCTCAATTTGGAGTGAGGCGCTTGGATAATTTTGCTATGGCCATGATGGCCTTGATGTTTCTC
ATGCCGAGTTTTCTCCTGACAACAGGCGGAGTCCTATCTTGCGCTTATGCCTTTATCATCACTATGTTGGATTTTGAGGA
TTTTAGTGGCTTTCGTAAAGCCGTACTAGAGAGTTTAAGTATCTCGTTAGGCATTTTACCGATTCTTATCCACTATTTTG
CAGAATTCCAACCTTGGTCTATCCTCTTGACCTTCCTTTTTTCAATCGTCTTTGATACATTTATGTTACCTCTCTTGAGT
CTAATTTTTCTCATTTCGCCTTTGTTTGCCTTCACTCAAGTTAATGTCTTCTTCCAATGGCTGGAAATGGTGATTCGTTG
GGTAGCTAGTTTGTCAACAAGGCCGATAATTTTAGGACAGCCAAATCTGCCTTTGCTTATTATTCTCCTGCTGGTCTTAG
CCTTGCTCTATGACTTTAGAAAACAAAAAAAGATTAGGGCTGGTCTGAGTCTCTTAGCAATCTTACTATTTTTCCTAAGT
AAATATCCTTTACAAAATGAAATCACAGTGGTAGATATTGGGCAGGGAGACAGTATATTTCTGAGGGATGTCAGAGGTAG
GACTATCGTGATTGATACAGGAGGACGGGTGGAGATTGGAAAAAAAGAAGCTTGGCAAGAGCGCGTGAGAAAAAGTAATG
CGGAAACGACCTTGATCCCTTATCTAAAAAGCCGAGGAGTGGATAGATTGGATAAATTGGTCTTGACTCACACCGATACA
GACCATATGGGAGATATGTTGGAGTTAGCTAAGCACTTTTCTATCCGAGAAATTTATGTTTCTAAAGGAAGTATGACTCA
AGTTGATTTTGTAGACAAGTTAAAGAAGATGAAAGCTAAAGTTCATGTGGTCGAGGTGGGAGATCGGCTTCCTATCTTTG
ATTCGGCCCTTGAAGTGCTCTATCCACTAGGTCAAGGAGATGGTGGTAATGATGACTCGATTGTCTTGTATGGTGAATTT
TTCCGGACCAAGTTTCTTTTCACAGGAGATTTAGAAGCTCCAGGTGAAGGTCAGATGGTGACAGCCTATCCAGATTTAAG
AGTAGATGTGCTCAAAGCTGGGCATCATGGTTCTAAAGGATCTTCTAGTCCAGAATTTCTAGAGCATATTAAGCCTAAGT
TGGCCTTGATTTCAGCTGGTAAAAACAACCGTTATCAACATCCCCATAAGGAAACTTTAGATAGATTCGAAAAAATCCAG
ACTAAGATTTTTCGGACAGATGAGCAGGGAGCTATTCGATTTAAAGGCTGGAATTCTTGGCAGATAGAAACGGTTCGCTA
G

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (35-174)

• Metallo-beta-lactamase superfamily (Lactamase_B) (494-700)

• Competence protein (Competence) (216-460)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	57.564	100	0.576
comEC/celB	Streptococcus mitis NCTC 12261	56.702	100	0.567
comEC/celB	Streptococcus pneumoniae TIGR4	56.359	100	0.564
comEC/celB	Streptococcus pneumoniae Rx1	55.823	100	0.559
comEC/celB	Streptococcus pneumoniae D39	55.823	100	0.559
comEC/celB	Streptococcus pneumoniae R6	55.823	100	0.559
comEC	Lactococcus lactis subsp. cremoris KW2	49.597	99.732	0.495