Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   MUA35_RS09290 Genome accession   NZ_CP094770
Coordinates   1904431..1905054 (-) Length   207 a.a.
NCBI ID   WP_001045133.1    Uniprot ID   A0A0H2XHP5
Organism   Staphylococcus aureus strain IVB6201     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1899431..1910054
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MUA35_RS09270 (MUA35_09240) - 1899923..1901119 (-) 1197 WP_000238224.1 exonuclease SbcCD subunit D -
  MUA35_RS09275 (MUA35_09245) - 1901895..1902239 (-) 345 WP_000290301.1 YlbF/YmcA family competence regulator -
  MUA35_RS09280 (MUA35_09250) - 1902308..1903432 (-) 1125 WP_262607581.1 DUF445 domain-containing protein -
  MUA35_RS09285 (MUA35_09255) - 1903611..1904075 (-) 465 WP_000375864.1 helix-turn-helix transcriptional regulator -
  MUA35_RS09290 (MUA35_09260) vraR 1904431..1905054 (-) 624 WP_001045133.1 response regulator transcription factor Regulator
  MUA35_RS09295 (MUA35_09265) - 1905076..1906188 (-) 1113 WP_000437967.1 GAF domain-containing sensor histidine kinase -
  MUA35_RS09300 (MUA35_09270) - 1906351..1907172 (+) 822 WP_000669377.1 RluA family pseudouridine synthase -
  MUA35_RS09305 (MUA35_09275) fumC 1907622..1909007 (-) 1386 WP_262607582.1 class II fumarate hydratase -
  MUA35_RS09310 (MUA35_09280) - 1909203..1909598 (-) 396 WP_000901023.1 hypothetical protein -

Sequence

Protein


Download         Length: 207 a.a.        Molecular weight: 23895.56 Da        Isoelectric Point: 5.5730

>NTDB_id=579174 MUA35_RS09290 WP_001045133.1 1904431..1905054(-) (vraR) [Staphylococcus aureus strain IVB6201]
MNKVILVDDHYIVRQGLRFLLSTIENIEVLQDFADGETFLEYLKEHEHPDIVLLDLVMPGMNGIEITEYIKAHYPDIKVL
VLTSYVDDEHVISAINKGADGYEMKDVEPQQLIETIRRVMNGEKMIHPKAQDVFETVSQKPHYTNKLSKREIEVLREMVK
GKTNKEIAETLFVSEKTIKTHVSHIFSKLQVSDRTQAAIYAMENKLI

Nucleotide


Download         Length: 624 bp        

>NTDB_id=579174 MUA35_RS09290 WP_001045133.1 1904431..1905054(-) (vraR) [Staphylococcus aureus strain IVB6201]
ATGAACAAAGTAATATTAGTAGATGACCATTATATTGTGCGACAAGGATTGCGATTTTTATTATCCACGATTGAAAACAT
AGAAGTTTTACAAGACTTTGCAGATGGAGAAACATTTTTAGAATATTTAAAAGAGCATGAGCACCCTGATATTGTGCTAT
TAGATTTAGTGATGCCTGGCATGAATGGTATTGAAATTACGGAATATATTAAGGCACATTATCCGGATATTAAAGTTTTG
GTATTAACAAGTTATGTAGATGATGAACATGTAATTTCAGCAATCAATAAAGGTGCTGATGGTTATGAAATGAAAGACGT
TGAGCCTCAGCAATTAATTGAAACTATTAGACGAGTTATGAACGGTGAAAAAATGATACATCCTAAGGCACAAGATGTAT
TCGAAACAGTTAGCCAAAAACCACACTACACGAATAAGTTGTCAAAGAGAGAAATTGAAGTGTTACGTGAAATGGTTAAA
GGTAAAACAAATAAAGAGATAGCAGAAACTTTATTTGTATCTGAAAAAACAATTAAAACACATGTCAGTCATATATTTAG
TAAATTACAAGTTAGCGATCGTACACAAGCAGCAATTTATGCAATGGAAAATAAGTTGATTTAG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-116)

Bacterial regulatory proteins, luxR family (GerE)

(146-201)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2XHP5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

40.58

100

0.406
  degU Bacillus subtilis subsp. subtilis str. 168

35.135

100

0.377
  letA Legionella pneumophila str. Paris

35.714

100

0.362
  letA Legionella pneumophila strain ERS1305867

35.714

100

0.362