Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   SPN032672_RS05310 Genome accession   NC_021003
Coordinates   1007543..1008250 (-) Length   235 a.a.
NCBI ID   WP_000166475.1    Uniprot ID   -
Organism   Streptococcus pneumoniae SPN032672     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1002543..1013250
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPN032672_RS05285 pstB 1002626..1003378 (-) 753 WP_000536450.1 phosphate ABC transporter ATP-binding protein PstB -
  SPN032672_RS05290 pstA 1003380..1004195 (-) 816 WP_000049768.1 phosphate ABC transporter permease PstA -
  SPN032672_RS05295 pstC 1004188..1005051 (-) 864 WP_000165893.1 phosphate ABC transporter permease subunit PstC -
  SPN032672_RS05300 - 1005169..1006044 (-) 876 WP_000669493.1 substrate-binding domain-containing protein -
  SPN032672_RS05305 pnpS 1006211..1007542 (-) 1332 WP_000833273.1 two-component system histidine kinase PnpS -
  SPN032672_RS05310 vicR 1007543..1008250 (-) 708 WP_000166475.1 response regulator transcription factor Regulator
  SPN032672_RS05315 - 1008334..1008819 (-) 486 WP_000035500.1 cupin domain-containing protein -
  SPN032672_RS05320 - 1008805..1009362 (+) 558 Protein_997 transposase family protein -
  SPN032672_RS05325 argS 1009698..1011389 (-) 1692 WP_001092701.1 arginine--tRNA ligase -
  SPN032672_RS05330 argR 1011525..1011971 (+) 447 WP_001231472.1 arginine repressor -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 27230.61 Da        Isoelectric Point: 6.6568

>NTDB_id=57870 SPN032672_RS05310 WP_000166475.1 1007543..1008250(-) (vicR) [Streptococcus pneumoniae SPN032672]
MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAETEPFDFILLDIMLPQLDGMEVCKRLRAKGVKTPIMMV
SAKSDEFDKVLALELGADDYLTKPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKAPQFIRTIRGYGYKFKEL

Nucleotide


Download         Length: 708 bp        

>NTDB_id=57870 SPN032672_RS05310 WP_000166475.1 1007543..1008250(-) (vicR) [Streptococcus pneumoniae SPN032672]
ATGACAAAACAAGTCTTATTAGTGGATGATGAAGAACACATTCTGAAATTGCTTGACTACCATTTAAGTAAGGAAGGCTT
TTCTACTCAATTGGTAACAAATGGACGGAAGGCCTTAGCTTTGGCAGAAACAGAACCCTTTGATTTTATCTTGCTTGATA
TCATGTTACCACAATTAGATGGCATGGAAGTTTGTAAGCGGCTGAGAGCCAAAGGCGTCAAAACTCCAATTATGATGGTT
TCTGCGAAAAGTGATGAATTTGATAAGGTTTTGGCCTTGGAATTAGGGGCTGATGACTACCTGACCAAGCCTTTTAGCCC
TAGAGAATTGCTGGCGCGTGTCAAGGCTGTCCTCAGGCGAACTAAAGGAGAACAAGAAGGAGATGATTCAGATAATATCG
CTGACGATTCTTGGCTATTTGGGACCTTGAAAGTATACCCTGAGCGTCATGAAGTCTACAAGGCGAATAAGTTACTGAGT
TTGACCCCAAAAGAATTTGAACTCTTGCTCTATCTTATGAAACATCCCAACATGACACTGACTAGAGAGCGTCTTTTGGA
ACGTATCTGGGGGTATGACTTTGGGCAGGAAACACGTTTGGTGGACGTTCATATTGGTAAGTTGAGGGAAAAAATTGAAG
ACAATCCTAAAGCCCCTCAATTTATTCGAACCATTCGGGGTTATGGTTATAAGTTCAAGGAGTTATAG

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(159-232)

Response regulator receiver domain (Response_reg)

(5-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

48.707

98.723

0.481
  micA Streptococcus pneumoniae Cp1015

47.845

98.723

0.472
  covR Lactococcus lactis subsp. lactis strain DGCC12653

40.773

99.149

0.404
  covR Streptococcus salivarius strain HSISS4

39.744

99.574

0.396

Multiple sequence alignment