Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   SPN032672_RS03830 Genome accession   NC_021003
Coordinates   728976..729635 (+) Length   219 a.a.
NCBI ID   WP_000565002.1    Uniprot ID   -
Organism   Streptococcus pneumoniae SPN032672     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 723976..734635
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPN032672_RS03810 - 724613..725509 (-) 897 WP_000825669.1 PEP phosphonomutase -
  SPN032672_RS03815 - 725512..726774 (-) 1263 WP_000413343.1 PTS sugar transporter subunit IIC -
  SPN032672_RS03820 - 727054..728232 (+) 1179 WP_000175876.1 ROK family transcriptional regulator -
  SPN032672_RS03825 - 728460..728906 (-) 447 WP_000155399.1 GNAT family N-acetyltransferase -
  SPN032672_RS03830 cclA/cilC 728976..729635 (+) 660 WP_000565002.1 prepilin peptidase Machinery gene
  SPN032672_RS03835 - 729687..730838 (-) 1152 WP_000481756.1 XRE family transcriptional regulator -
  SPN032672_RS03840 - 730853..731584 (-) 732 WP_000934017.1 hypothetical protein -
  SPN032672_RS11795 - 731804..731914 (+) 111 Protein_735 prepilin peptidase -
  SPN032672_RS03845 trpA 731886..732662 (-) 777 WP_001127048.1 tryptophan synthase subunit alpha -
  SPN032672_RS03850 trpB 732655..733878 (-) 1224 WP_000331287.1 tryptophan synthase subunit beta -
  SPN032672_RS03855 - 733856..734455 (-) 600 WP_000169887.1 phosphoribosylanthranilate isomerase -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24806.89 Da        Isoelectric Point: 7.2761

>NTDB_id=57850 SPN032672_RS03830 WP_000565002.1 728976..729635(+) (cclA/cilC) [Streptococcus pneumoniae SPN032672]
MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTPLRPLDLIPILSQVFNRFRCRYCKVRYPVWYALFELGLG
LLFLLYSWELLSLGQVVLITAGLTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCVIIFGKLLLV

Nucleotide


Download         Length: 660 bp        

>NTDB_id=57850 SPN032672_RS03830 WP_000565002.1 728976..729635(+) (cclA/cilC) [Streptococcus pneumoniae SPN032672]
ATGATTGATTTTTATTTTTTTCTCGTCGGGAGCATTCTCGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGCA
ATCCATTATCAGTTCAGCCAGTCACTGCGATTCCTGTCAGACTCCCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCAC
AGGTCTTCAATCGCTTTCGCTGTCGCTACTGCAAAGTTCGCTATCCTGTCTGGTATGCCCTCTTTGAACTAGGCTTAGGA
CTCCTCTTTCTGCTTTACTCTTGGGAATTGCTTTCCTTGGGGCAAGTCGTCCTAATCACCGCTGGTTTGACCTTGGGTAT
ATACGACTTTCACCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTAATAGCTTCCTCTGGCTGGA
ATCTGGTCATGGTCTCCTTCCTCATACTTGGAATTTTGGCTCATTTTATTGATATCCGCATGGGTGCAGGGGATTTCCTC
TTTTTAGCTTCTTGTGCTCTCGTCTTTAGCGTAACGGAGTTACTGATCTTGATTCAGTTCGCTTCTGCGACGGGTATCCT
GGCCTTTCTCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTACTTGTGTGATTATTTTTG
GTAAGCTACTACTTGTTTGA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-89)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus pneumoniae TIGR4

97.717

100

0.977
  cclA/cilC Streptococcus pneumoniae Rx1

97.26

100

0.973
  cclA/cilC Streptococcus pneumoniae D39

97.26

100

0.973
  cclA/cilC Streptococcus pneumoniae R6

97.26

100

0.973
  cclA/cilC Streptococcus mitis SK321

92.694

100

0.927
  cclA/cilC Streptococcus mitis NCTC 12261

87.671

100

0.877

Multiple sequence alignment