Detailed information NTG0057834

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: KK0981_RS04685
• Genome accession: NZ_AP017971
• Coordinates: 870791..873031 (+)
• Length: 746 a.a.
• NCBI ID: WP_000942411.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain KK0981
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 865791..878031

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KK0981_RS04650 (KK0981_29150)	pyrH	865881..866618 (+)	738	WP_000002997.1	UMP kinase	-
KK0981_RS04655 (KK0981_29160)	frr	866627..867184 (+)	558	WP_000024409.1	ribosome recycling factor	-
KK0981_RS04660 (KK0981_29170)	cvfB	867244..868098 (+)	855	WP_001095450.1	RNA-binding virulence regulatory protein CvfB	-
KK0981_RS04665 (KK0981_29180)	-	868107..868322 (+)	216	WP_001232082.1	YozE family protein	-
KK0981_RS04670 (KK0981_29190)	-	868408..869412 (+)	1005	WP_000658177.1	PhoH family protein	-
KK0981_RS04675 (KK0981_29200)	-	869520..870089 (+)	570	WP_000443770.1	GNAT family N-acetyltransferase	-
KK0981_RS04680 (KK0981_29210)	comEA/celA/cilE	870157..870807 (+)	651	WP_000387330.1	ComEA family DNA-binding protein	Machinery gene
KK0981_RS04685 (KK0981_29220)	comEC/celB	870791..873031 (+)	2241	WP_000942411.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
KK0981_RS04690 (KK0981_29230)	-	873075..874028 (-)	954	WP_001155321.1	IS30-like element ISSpn8 family transposase	-
KK0981_RS04695 (KK0981_29240)	infC	874515..875045 (+)	531	WP_000848180.1	translation initiation factor IF-3	-
KK0981_RS04700 (KK0981_29250)	rpmI	875078..875278 (+)	201	WP_001125943.1	50S ribosomal protein L35	-
KK0981_RS04705 (KK0981_29260)	rplT	875330..875689 (+)	360	WP_000124836.1	50S ribosomal protein L20	-
KK0981_RS04710 (KK0981_29270)	-	875747..876127 (+)	381	WP_000157154.1	VOC family protein	-
KK0981_RS04715 (KK0981_29280)	-	876377..877177 (+)	801	WP_001070101.1	dihydroorotate dehydrogenase electron transfer subunit	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84671.30 Da
• Isoelectric Point: 9.5148

>NTDB_id=57834 KK0981_RS04685 WP_000942411.1 870791..873031(+) (comEC/celB) [Streptococcus pneumoniae strain KK0981]
MLQWIKNFSIPLIYLSFLLLWLYYAIFSTSYLALLGFVFLLVCLFFQFPWKSASKVLVICGIFGFWFVFQNWQQSQASQN
LADSVERVRILPDTIKVNGDSLSFRGKSNGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFDYQGY
LKTQGIYQTLNIKRIQSLQKVGSWDIGENLSSLRRKAVVWIKMHFPDPMRNYMTGLLLGHLDTDFEEMNELYSSLGIIHL
FALSGMQVGFFMDGFKKLLLRLGLTQEKLKWLTYPFSLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIV
MPNFFLTAGGVLSCAYAFILTMTSKEGEGLKAVTSESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDLVFLPLLSI
LFVLSFLYPVIQLNFIFEWLEGIIRLVSQVASRPLVFGQPNEWLLILLLISLALVYDLRKNIKKLTVLCLLITGLFLLTK
HPLENEITMLDVGQGESIFLRDVTGKTILIDVGGKAESYKKIKKWQEKMTTSNAQRTLIPYLKSRGVAKIDQLILTNTDK
EHVGDLSEMTKAFHVGEILVSKDSLKQKEFVAELQATQTKVRSMIVGENLPIFGSQLEVLSPRKMGDGGHDDTLVLYGKF
LDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQHGSKKSSSPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGIN
SKVYRTDQQGAIRFKGLDSWKIESVR

Nucleotide

• Length: 2241 bp

>NTDB_id=57834 KK0981_RS04685 WP_000942411.1 870791..873031(+) (comEC/celB) [Streptococcus pneumoniae strain KK0981]
ATGTTACAGTGGATTAAGAATTTCTCTATTCCCCTAATTTACCTGAGTTTTCTGTTACTTTGGCTTTACTACGCCATTTT
TTCAACATCCTATCTTGCTTTGTTGGGATTTGTTTTTCTGCTAGTCTGTCTCTTTTTCCAATTTCCTTGGAAATCTGCTA
GCAAAGTTCTAGTGATTTGTGGAATCTTTGGATTTTGGTTTGTTTTTCAAAATTGGCAACAGAGTCAAGCGAGTCAAAAT
CTGGCGGATTCTGTTGAAAGGGTACGGATTTTGCCTGATACTATTAAGGTTAATGGTGATAGTCTATCCTTTCGTGGCAA
GTCTAACGGTCGTGCTTTCCAAGTCTATTATAAACTCCAGTCCGAGGAGGAGAAAGAAGCCTTTCAAGCTTTAACCGACC
TGCATGAGATAGGACTAGAAGGGAAGCTTTCGGAGCCAGAAGGGCAGAGAAATTTTGGTGGCTTTGACTACCAAGGCTAT
CTGAAGACTCAGGGAATTTACCAGACACTCAATATTAAAAGAATCCAGTCACTCCAAAAGGTTGGCAGTTGGGATATAGG
TGAAAACCTGTCCAGTTTACGTCGAAAGGCTGTGGTTTGGATTAAGATGCACTTCCCAGACCCTATGCGCAATTACATGA
CAGGACTCTTGCTAGGACATCTGGACACCGATTTTGAGGAGATGAATGAGCTTTATTCCAGTTTAGGAATTATTCACCTT
TTTGCCTTGTCAGGTATGCAGGTAGGGTTTTTCATGGACGGATTTAAGAAACTACTTTTACGATTGGGCTTGACACAAGA
AAAGTTGAAGTGGCTGACTTATCCCTTTTCCCTTATCTATGCGGGACTAACTGGATTTTCAGCATCGGTTATTCGCAGTC
TCTTGCAAAAGCTACTGGCTCAACATGGGGTTAAGGGCTTGGATAATTTTGCCTTGACGGTGCTTGTCCTCTTTATTGTC
ATGCCAAACTTTTTCTTGACAGCAGGAGGAGTCTTGTCCTGCGCTTATGCTTTTATCCTGACCATGACCAGCAAAGAAGG
GGAGGGGCTCAAGGCTGTTACTAGTGAAAGTCTAGTCATCTCCTTGGGCATATTGCCCATTCTATCCTTCTATTTTGCGG
AATTTCAACCTTGGTCTATCCTTTTGACCTTTGTCTTTTCCTTTCTTTTTGACTTGGTCTTCTTACCGCTCTTGTCTATC
TTATTTGTCCTTTCCTTTCTCTATCCAGTCATTCAGCTGAACTTTATCTTTGAATGGTTAGAGGGCATTATTCGCTTGGT
CTCGCAGGTGGCAAGTAGACCGCTTGTCTTTGGACAACCCAATGAATGGCTTTTAATCCTATTGTTAATTTCTTTGGCTT
TGGTCTATGATTTGAGGAAAAACATTAAAAAGCTAACGGTATTGTGCTTATTGATTACAGGGCTCTTTCTCCTGACCAAG
CATCCACTGGAAAATGAAATCACCATGCTGGATGTGGGGCAAGGAGAAAGTATTTTCCTACGGGATGTAACTGGGAAAAC
CATTCTCATAGATGTAGGTGGTAAGGCAGAATCTTATAAGAAAATCAAAAAATGGCAAGAAAAGATGACGACCAGCAATG
CCCAGCGAACCTTGATTCCCTATCTCAAAAGTCGAGGAGTAGCTAAGATTGACCAGCTAATTTTGACTAACACGGACAAG
GAGCATGTTGGAGATTTGTCAGAGATGACCAAGGCTTTCCATGTAGGGGAGATTCTAGTATCAAAAGACAGTCTGAAACA
GAAGGAATTTGTGGCAGAACTACAGGCGACTCAAACAAAGGTGCGTAGTATGATAGTAGGGGAGAACTTGCCCATTTTTG
GAAGTCAGTTAGAAGTTCTATCTCCAAGGAAAATGGGAGATGGAGGACACGATGATACCCTAGTTCTGTATGGGAAATTC
TTGGATAAGCAATTTCTCTTCACGGGAAATTTGGAGGAGAAAGGAGAGAAGGACTTGCTGAAGCACTATCCAGACTTGAA
AGTAAATGTTTTGAAAGCTAGCCAACATGGCTCTAAAAAATCATCAAGTCCAGCCTTTCTAGAAAAACTCAAACCAGAGC
TTACTCTTATCTCAGTTGGAAAGAGCAATCGAATGAAACTCCCCCATCAGGAAACATTGACACGACTGGAAGGTATCAAT
AGCAAAGTTTATCGAACTGACCAGCAAGGAGCTATACGTTTTAAGGGGTTGGATAGTTGGAAAATCGAAAGTGTTCGATA
G

Domains

Predicted by InterProScan.

• Domain of unknown function (DUF4131) (DUF4131) (31-176)

• Competence protein (Competence) (216-458)

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-697)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus pneumoniae TIGR4	97.587	100	0.976
comEC/celB	Streptococcus pneumoniae D39	97.051	100	0.971
comEC/celB	Streptococcus pneumoniae R6	97.051	100	0.971
comEC/celB	Streptococcus pneumoniae Rx1	97.051	100	0.971
comEC/celB	Streptococcus mitis SK321	92.091	100	0.921
comEC/celB	Streptococcus mitis NCTC 12261	91.812	99.866	0.917
comEC	Lactococcus lactis subsp. cremoris KW2	44.669	99.33	0.444