Detailed information    

insolico Bioinformatically predicted

Overview

Name   pknB   Type   Regulator
Locus tag   CCX78_RS06285 Genome accession   NZ_AP017931
Coordinates   1222843..1224726 (-) Length   627 a.a.
NCBI ID   WP_096585199.1    Uniprot ID   -
Organism   Latilactobacillus sakei strain LK-145     
Function   modulate the activity of ComDE; modulate the activity of VicKR (predicted from homology)   
Competence regulation

Genomic Context

Location: 1217843..1229726
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CCX78_RS06260 (LASAK_01250) - 1219322..1219684 (-) 363 WP_011374405.1 Asp23/Gls24 family envelope stress response protein -
  CCX78_RS06265 (LASAK_01251) rpmB 1219987..1220172 (+) 186 WP_004265581.1 50S ribosomal protein L28 -
  CCX78_RS06270 (LASAK_01252) - 1220521..1221171 (-) 651 WP_011374404.1 thiamine diphosphokinase -
  CCX78_RS06275 (LASAK_01253) rpe 1221158..1221820 (-) 663 WP_011374403.1 ribulose-phosphate 3-epimerase -
  CCX78_RS06280 (LASAK_01254) rsgA 1221844..1222743 (-) 900 WP_096585196.1 ribosome small subunit-dependent GTPase A -
  CCX78_RS06285 (LASAK_01255) pknB 1222843..1224726 (-) 1884 WP_096585199.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  CCX78_RS06290 (LASAK_01256) - 1224723..1225469 (-) 747 WP_025015868.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  CCX78_RS06295 (LASAK_01257) rsmB 1225491..1226834 (-) 1344 WP_096585202.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  CCX78_RS06300 (LASAK_01258) fmt 1226824..1227780 (-) 957 WP_096585205.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 627 a.a.        Molecular weight: 68136.71 Da        Isoelectric Point: 5.8384

>NTDB_id=57766 CCX78_RS06285 WP_096585199.1 1222843..1224726(-) (pknB) [Latilactobacillus sakei strain LK-145]
MMETGYAVAGRYKIIRPIGEGGMANVYLAQDLILDRQVAVKVLRLDLRNDPDTVRRFTREALATTELNHPNIVSIYDVGE
ENSMQYIIMEYIKGTDLKKYIVEHFPIPYQRVIDIMTQILSAVQNAHAHNIIHRDLKPQNILVDEDGNVKISDFGIAIAL
SETAMTQTNTLLGSVHYLSPEQARGSMATKRSDIYSLGIVLYELLTGMVPFEGESAVSIAIKHFQDEVPPVRNYDPRIPQ
ALENVVLKATAKDPDERYSGVDAMMADLATSLSASRAHEPKFVPSKADDLSETKVIPALDPEGITQTSNDEEQVKEAEST
QKKVKKPAKSKRKWWLLGGGVVLLLLLATVIAFAVQGSEVTVPDLTDMTQQNAESALTDKKLKVGTVQKTTSQKYSKGHV
IRTTPKAGLSVKSKSTVNLIVSSGRQKYKIKDYTNQAYSDVRDALKDKGLTVKRKYQSSSEVSPGLIIDQSIAAGKRVVP
SKTTITLTVSSGKPGFALHNLSNYTKQGIQDYAAQNGLTVVFSEEYSSSISEGMVISQSPASGTMVQEGDSVSVILSKGE
QPTEHHSIVTSSSNSVIESSAPESSQSSESSASESESESESESESESASESISSSASQSSQSSVQSK

Nucleotide


Download         Length: 1884 bp        

>NTDB_id=57766 CCX78_RS06285 WP_096585199.1 1222843..1224726(-) (pknB) [Latilactobacillus sakei strain LK-145]
ATGATGGAAACAGGGTACGCTGTAGCGGGGCGTTATAAGATTATTCGGCCCATTGGTGAAGGCGGCATGGCTAATGTTTA
TTTGGCGCAGGATCTAATTTTAGACCGGCAAGTGGCAGTTAAAGTTTTACGATTAGATCTCCGAAATGATCCGGATACAG
TCCGACGGTTTACGCGAGAAGCGTTGGCAACGACTGAATTAAATCATCCGAATATTGTTAGTATTTACGATGTTGGTGAA
GAAAACAGTATGCAGTACATCATTATGGAATATATTAAGGGCACCGATCTTAAGAAATATATCGTGGAACACTTTCCAAT
TCCTTATCAACGTGTAATTGATATTATGACGCAGATTTTATCTGCGGTTCAAAACGCACATGCGCATAATATTATTCATC
GGGATTTAAAACCACAAAATATTTTGGTTGATGAAGACGGCAATGTTAAGATTAGTGACTTTGGGATTGCGATTGCGCTC
AGCGAAACAGCGATGACTCAGACCAACACGTTGTTGGGGTCTGTGCATTATCTCTCACCGGAACAGGCAAGAGGCTCGAT
GGCGACGAAACGGTCTGATATTTACTCGTTAGGAATTGTGCTTTATGAGTTATTGACGGGGATGGTGCCTTTTGAAGGCG
AGTCCGCTGTTTCAATTGCGATTAAGCATTTCCAAGATGAAGTCCCACCAGTACGCAACTATGATCCACGTATTCCGCAA
GCCCTGGAAAATGTCGTTTTAAAAGCGACTGCCAAGGATCCGGATGAACGCTATAGTGGTGTTGATGCCATGATGGCTGA
CTTAGCAACTTCTTTATCAGCTAGTCGTGCGCACGAACCTAAATTTGTGCCATCAAAAGCGGATGATTTGAGTGAGACTA
AGGTGATTCCTGCACTAGATCCAGAAGGCATTACGCAAACCAGCAACGATGAGGAACAAGTTAAAGAAGCAGAATCAACT
CAGAAAAAGGTTAAAAAGCCAGCTAAGTCTAAGCGTAAGTGGTGGCTACTAGGTGGCGGTGTTGTTTTATTGCTGTTATT
AGCAACGGTGATTGCTTTTGCAGTTCAGGGGAGCGAAGTAACCGTCCCTGATTTAACGGATATGACACAACAAAATGCGG
AATCTGCTTTGACCGATAAAAAACTGAAAGTCGGCACGGTTCAAAAAACAACGAGTCAGAAATACAGTAAGGGCCACGTC
ATTCGAACAACACCTAAAGCGGGCCTGAGTGTAAAATCAAAAAGTACGGTTAATTTAATTGTCAGTTCAGGACGCCAAAA
GTATAAGATTAAAGACTATACGAACCAAGCATATAGTGATGTTCGGGATGCTTTGAAGGATAAAGGCTTGACCGTTAAAC
GGAAATACCAAAGTTCATCTGAAGTGAGTCCTGGGTTGATTATCGATCAAAGTATTGCGGCTGGCAAAAGGGTCGTTCCA
AGTAAAACGACGATTACCTTAACAGTCAGCAGCGGCAAACCTGGTTTTGCATTGCATAATCTAAGCAACTATACAAAGCA
AGGGATTCAAGACTATGCTGCACAAAATGGTTTAACGGTCGTATTCTCTGAAGAATATTCATCAAGTATTTCTGAAGGAA
TGGTAATCAGTCAATCGCCTGCAAGTGGTACAATGGTTCAAGAAGGTGATAGCGTAAGCGTTATCCTTTCAAAAGGCGAG
CAACCAACTGAACATCATTCTATTGTGACGTCGAGTTCAAATTCAGTTATCGAGTCGAGTGCGCCTGAATCAAGTCAATC
GAGTGAAAGTAGCGCGAGTGAGTCAGAGAGCGAATCAGAGAGTGAATCGGAAAGCGAATCAGCAAGTGAATCGATCAGTA
GTTCAGCTAGTCAAAGTAGTCAATCGAGCGTTCAATCAAAGTAA

Domains

Predicted by InterProScan.

PASTA domain (PASTA)

(429-490)

PASTA domain (PASTA)

(360-422)

PASTA domain (PASTA)

(500-558)

Protein kinase domain (Pkinase)

(12-263)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pknB Streptococcus mutans UA159

42.393

93.301

0.396
  stkP Streptococcus pneumoniae TIGR4

40.304

94.577

0.381
  stkP Streptococcus pneumoniae D39

40.135

94.577

0.38
  stkP Streptococcus pneumoniae R6

40.135

94.577

0.38
  stkP Streptococcus pneumoniae Rx1

39.966

94.577

0.378

Multiple sequence alignment