Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   KQ224_RS01590 Genome accession   NZ_CP076721
Coordinates   309933..311306 (-) Length   457 a.a.
NCBI ID   WP_216806855.1    Uniprot ID   -
Organism   Streptococcus parasuis strain H35     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 304933..316306
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KQ224_RS01565 (KQ224_01565) - 305418..306695 (-) 1278 WP_216806853.1 pyrimidine-nucleoside phosphorylase -
  KQ224_RS01570 (KQ224_01570) - 306692..307282 (-) 591 WP_171988423.1 class I SAM-dependent methyltransferase -
  KQ224_RS01575 (KQ224_01575) coaA 307358..308278 (+) 921 WP_171988422.1 type I pantothenate kinase -
  KQ224_RS01580 (KQ224_01580) rpsT 308337..308585 (+) 249 WP_216806854.1 30S ribosomal protein S20 -
  KQ224_RS01585 (KQ224_01585) - 308619..309845 (-) 1227 WP_253952839.1 transglutaminase domain-containing protein -
  KQ224_RS01590 (KQ224_01590) ciaH 309933..311306 (-) 1374 WP_216806855.1 cell wall metabolism sensor histidine kinase WalK Regulator
  KQ224_RS01595 (KQ224_01595) ciaR 311299..311970 (-) 672 WP_024392086.1 response regulator transcription factor Regulator
  KQ224_RS01600 (KQ224_01600) - 312067..312444 (-) 378 WP_216806856.1 hypothetical protein -
  KQ224_RS01605 (KQ224_01605) - 312699..313469 (-) 771 WP_216806857.1 glycosyltransferase -
  KQ224_RS01610 (KQ224_01610) - 313459..313815 (-) 357 WP_216806858.1 DUF2304 domain-containing protein -
  KQ224_RS01615 (KQ224_01615) - 313815..314531 (-) 717 WP_216806859.1 glycosyltransferase family 2 protein -
  KQ224_RS01620 (KQ224_01620) - 314548..315807 (-) 1260 WP_216806860.1 lipopolysaccharide biosynthesis protein -

Sequence

Protein


Download         Length: 457 a.a.        Molecular weight: 51470.55 Da        Isoelectric Point: 5.0182

>NTDB_id=577560 KQ224_RS01590 WP_216806855.1 309933..311306(-) (ciaH) [Streptococcus parasuis strain H35]
MSKRFKKIISTDKFSFFIRYFAVFTLIFGLMTAIIFQLMRSTMYQTSDSTLARIKDAPALVVGFAIARTYEPNSEFIIQD
GNIADESDSAESNSDTPNSPKNQKDDQLKLGYNTHVLLYSNDGVVVNPDNFTGLSELSLDKKNLGEIKEVTVDSTFGGSE
DYRYVTIELAPDDLGYYSSYDIKYATIFVNVSQIKSSIETYETAVAIVMVSAWLISILASIYLSNLSMRPILISYQKQKD
FVENASHELRTPLTVLQNRLEGLFRHPNATILESSESIGSSLEEVRNMRMLTTNLLNLARRDDGFKLDIVEVPPSYFDEI
FENYMMIADENGKTVTVNNLIDQPIRTDKVLVKQLLTILFDNAMKYTEDDGTIQVTANIKDKSVYFTVADNGLGISDSDK
KKIFDRFYRVDKARTRSKGGFGLGLSLALQISNSLKGTITVRDNQPKGTIFEVRLPR

Nucleotide


Download         Length: 1374 bp        

>NTDB_id=577560 KQ224_RS01590 WP_216806855.1 309933..311306(-) (ciaH) [Streptococcus parasuis strain H35]
ATGTCTAAGCGATTTAAAAAAATCATTTCAACAGATAAATTTTCCTTTTTTATCAGATATTTTGCTGTTTTTACACTCAT
TTTCGGATTAATGACGGCCATTATCTTCCAGTTAATGCGCTCAACTATGTATCAGACTTCGGATTCAACACTGGCTCGTA
TCAAAGATGCCCCTGCTTTGGTGGTTGGTTTTGCCATTGCACGGACCTATGAACCAAATTCAGAATTCATTATTCAAGAC
GGAAATATTGCTGATGAAAGTGATTCTGCAGAATCTAATTCAGATACACCAAACTCCCCTAAAAATCAGAAAGACGATCA
GTTGAAACTTGGTTACAATACACATGTATTACTCTATTCAAATGATGGTGTAGTCGTTAATCCAGATAACTTTACAGGAC
TTTCTGAGTTATCCTTAGACAAGAAAAATTTAGGCGAAATAAAGGAAGTAACGGTTGATTCTACATTCGGGGGTTCAGAA
GATTATCGTTACGTTACTATTGAATTGGCGCCAGATGACCTTGGCTATTATTCTTCCTATGATATTAAATACGCGACAAT
TTTCGTGAATGTGAGTCAGATAAAATCATCCATTGAGACGTATGAAACTGCTGTAGCTATTGTCATGGTATCTGCTTGGC
TTATTTCCATCTTGGCTAGTATTTATCTGTCAAATTTGAGTATGCGACCTATCTTAATTAGCTATCAAAAACAAAAGGAT
TTCGTTGAGAATGCTAGTCATGAATTGAGAACGCCTCTAACTGTGTTACAGAATCGTTTGGAAGGTCTTTTTAGACATCC
AAATGCAACCATTTTGGAAAGTAGTGAGAGTATAGGATCAAGCCTAGAGGAAGTTCGTAATATGCGTATGTTAACTACGA
ATTTACTGAATTTAGCTCGTCGAGATGATGGTTTCAAATTAGATATAGTTGAAGTCCCACCTAGCTATTTTGATGAAATC
TTTGAGAATTACATGATGATTGCAGATGAAAATGGTAAAACAGTCACGGTTAATAATTTGATTGATCAACCAATTCGGAC
GGATAAGGTGTTGGTAAAACAGCTTCTAACCATCCTATTTGATAATGCAATGAAGTATACCGAAGATGATGGCACTATAC
AAGTGACAGCCAATATCAAAGATAAGTCAGTTTACTTTACGGTAGCAGACAATGGATTGGGTATCAGTGATAGTGATAAA
AAGAAAATTTTCGATCGATTTTATCGTGTAGACAAGGCCCGTACTCGGAGCAAGGGTGGGTTTGGTCTCGGTTTATCCTT
AGCCTTACAAATTTCCAATAGTTTGAAAGGCACAATCACTGTGCGGGATAATCAGCCTAAAGGAACTATTTTTGAGGTAA
GATTGCCGAGATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(238-304)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(348-456)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

50.439

99.781

0.503
  ciaH Streptococcus pneumoniae D39

50.439

99.781

0.503
  ciaH Streptococcus pneumoniae R6

50.439

99.781

0.503
  ciaH Streptococcus pneumoniae TIGR4

50.439

99.781

0.503
  ciaH Streptococcus mutans UA159

49.89

99.125

0.495