NTDB

Overview

Name	covR	Type	Regulator
Locus tag	KRG72_RS07490	Genome accession	NZ_CP076703
Coordinates	1505955..1506647 (-)	Length	230 a.a.
NCBI ID	WP_006532917.1	Uniprot ID	A0A380KNN3
Organism	Streptococcus equinus strain S1
Function	repress comR expression (predicted from homology) Competence regulation

Genomic Context

Location: 1500955..1511647

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KRG72_RS07470 (KRG72_07480)	dnaI	1501759..1502661 (-)	903	WP_074560813.1	primosomal protein DnaI	-
KRG72_RS07475 (KRG72_07485)	-	1502672..1503823 (-)	1152	WP_258250381.1	DnaD domain protein	-
KRG72_RS07480 (KRG72_07490)	nrdR	1503810..1504304 (-)	495	WP_074560815.1	transcriptional regulator NrdR	-
KRG72_RS07485 (KRG72_07495)	-	1504486..1505955 (-)	1470	WP_258250382.1	HAMP domain-containing histidine kinase	-
KRG72_RS07490 (KRG72_07500)	covR	1505955..1506647 (-)	693	WP_006532917.1	response regulator transcription factor	Regulator
KRG72_RS07495 (KRG72_07505)	-	1506888..1507424 (-)	537	WP_258250383.1	DUF177 domain-containing protein	-
KRG72_RS07500 (KRG72_07510)	htpX	1507566..1508465 (-)	900	WP_039696378.1	zinc metalloprotease HtpX	-
KRG72_RS07505 (KRG72_07515)	-	1508578..1509129 (-)	552	WP_014335211.1	LemA family protein	-
KRG72_RS07510 (KRG72_07520)	rsmG	1509419..1510132 (+)	714	WP_258250384.1	16S rRNA (guanine(527)-N(7))-methyltransferase RsmG	-
KRG72_RS07515 (KRG72_07525)	-	1510208..1511581 (+)	1374	WP_258250385.1	TrkH family potassium uptake protein	-

Sequence

Protein

Download Length: 230 a.a. Molecular weight: 26400.31 Da Isoelectric Point: 4.7654

                                >NTDB_id=577475 KRG72_RS07490 WP_006532917.1 1505955..1506647(-) (covR) [Streptococcus equinus strain S1]

MSKKILIIEDEKNLARFVSLELQHEGYSVVVETNGRLGLQTALDDDFDLILLDLMLPDMDGFEITRRLRLEKDTSIIMMT

ARDSIMDIVAGLDRGADDYIVKPFAIEELLARVRAVFRRQDANSKQDKEGQAKEGLLGLRLNPQNRSAVRGDDEISLTKR

EYDLLSVLLSNVNRVMTREELLASVWRYDTDIETNVVDVYIRYLRGKIDIPGKESYIQTVRGMGYIIREK

Nucleotide

Download Length: 693 bp

                                >NTDB_id=577475 KRG72_RS07490 WP_006532917.1 1505955..1506647(-) (covR) [Streptococcus equinus strain S1]

ATGAGTAAAAAGATTTTAATTATTGAGGATGAAAAAAATCTTGCACGCTTTGTGTCTTTAGAATTACAACATGAGGGGTA

TTCAGTAGTTGTTGAGACAAATGGACGTTTAGGGCTTCAAACTGCATTGGATGATGATTTTGATTTGATCCTATTAGATT

TGATGTTACCTGATATGGACGGATTCGAAATTACACGTCGTCTTCGTTTGGAAAAAGACACATCAATTATCATGATGACT

GCTCGTGATTCTATTATGGATATTGTTGCTGGTCTTGACCGTGGAGCAGATGATTATATTGTAAAACCATTTGCTATTGA

AGAATTACTCGCTCGTGTTCGTGCAGTATTCCGTCGTCAAGATGCTAATTCTAAACAAGACAAAGAAGGTCAAGCAAAAG

AAGGTCTCTTAGGTCTTCGTTTGAACCCACAAAATCGTTCTGCAGTTCGTGGTGATGATGAAATTTCATTAACAAAACGT

GAATACGATTTGTTGAGCGTGCTACTTTCAAATGTTAATCGCGTAATGACACGTGAAGAACTTTTGGCAAGTGTTTGGCG

TTATGATACAGACATCGAAACAAATGTAGTGGATGTTTACATCCGTTACCTACGTGGTAAAATTGATATTCCTGGTAAAG

AATCATATATCCAAACAGTTCGTGGAATGGGTTATATTATTCGAGAAAAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(153-226)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure
AlphaFold DB	A0A380KNN3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
covR	Streptococcus salivarius strain HSISS4	76.087	100	0.761
covR	Lactococcus lactis subsp. lactis strain DGCC12653	64.192	99.565	0.639
micA	Streptococcus pneumoniae Cp1015	41.739	100	0.417
vicR	Streptococcus mutans UA159	41.558	100	0.417

Detailed information NTG0577475