Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   KRG72_RS06735 Genome accession   NZ_CP076703
Coordinates   1359093..1360445 (-) Length   450 a.a.
NCBI ID   WP_039696510.1    Uniprot ID   A0AAE6UZR7
Organism   Streptococcus equinus strain S1     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1354093..1365445
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KRG72_RS06725 (KRG72_06735) rnc 1357375..1358061 (-) 687 WP_020917219.1 ribonuclease III -
  KRG72_RS06730 (KRG72_06740) vicX 1358283..1359092 (-) 810 WP_258250301.1 MBL fold metallo-hydrolase Regulator
  KRG72_RS06735 (KRG72_06745) vicK 1359093..1360445 (-) 1353 WP_039696510.1 cell wall metabolism sensor histidine kinase VicK Regulator
  KRG72_RS06740 (KRG72_06750) vicR 1360438..1361148 (-) 711 WP_039696509.1 response regulator YycF Regulator
  KRG72_RS06745 (KRG72_06755) - 1361460..1362224 (+) 765 WP_039696508.1 amino acid ABC transporter ATP-binding protein -
  KRG72_RS06750 (KRG72_06760) - 1362235..1363047 (+) 813 WP_074602531.1 transporter substrate-binding domain-containing protein -
  KRG72_RS06755 (KRG72_06765) - 1363063..1363770 (+) 708 WP_039696506.1 amino acid ABC transporter permease -
  KRG72_RS06760 (KRG72_06770) - 1363783..1364430 (+) 648 WP_006532766.1 amino acid ABC transporter permease -
  KRG72_RS06765 (KRG72_06775) - 1364468..1365076 (-) 609 WP_006532767.1 TVP38/TMEM64 family protein -

Sequence

Protein


Download         Length: 450 a.a.        Molecular weight: 51378.34 Da        Isoelectric Point: 4.7359

>NTDB_id=577471 KRG72_RS06735 WP_039696510.1 1359093..1360445(-) (vicK) [Streptococcus equinus strain S1]
MNDTMVQNQYLFEQAILFLLAFVAIYFIHLAIRDYRTSVNIRRLSGKVRELITGKYTEDIIIEKDRDLAELAGQLNDLST
VFRLAQENLAQEKNRLASILSYMTDGVLATDRSGNITMINQTAQKQLNLEREEALGMNIVDILGDDSDYSYHDLVSKTPE
IVLNRRDETGEFITLRIRFALNRRDSGFISGLIAVLHDTTEQEKEDRERRLFVSNVSHELRTPLTSVKSYLEALDEGALK
EDIAPSFIKVSLDETNRMIRMISDLLNLSRIDNQTVQLEVEMTNFTAFMTSILNRFDQIKSQHTVAGKQYEIVRDYPIKS
IWVEIDPDKMTQVLDNILNNAIKYSPDGGKITVSMKTTETQLIISISDEGLGIPKKDLPLIFDRFYRVDKARSRAQGGSG
LGLAIAKEIVKQHKGFIWAQSTYGKGSTFTIVLPYEKDSDIYDEWEDDED

Nucleotide


Download         Length: 1353 bp        

>NTDB_id=577471 KRG72_RS06735 WP_039696510.1 1359093..1360445(-) (vicK) [Streptococcus equinus strain S1]
ATGAATGATACAATGGTACAGAATCAATATCTGTTTGAACAAGCCATTCTTTTCTTGTTAGCTTTTGTAGCCATTTATTT
TATTCATTTGGCTATCAGAGACTATAGAACGTCTGTTAATATTCGCCGATTGAGTGGTAAGGTTCGTGAACTGATTACAG
GAAAATACACAGAAGATATTATCATTGAAAAAGACAGAGATTTAGCAGAGCTGGCTGGTCAGTTAAATGATTTGTCAACT
GTCTTTCGTTTGGCTCAAGAAAATCTAGCCCAAGAAAAGAATCGTTTAGCAAGTATTTTGTCTTACATGACTGATGGGGT
GCTAGCGACTGACCGTTCTGGAAATATCACCATGATTAACCAGACCGCTCAAAAGCAACTAAATCTTGAACGTGAAGAAG
CTCTTGGGATGAATATCGTTGATATTCTTGGTGATGATAGTGATTATTCTTACCATGATTTGGTGTCTAAGACGCCAGAA
ATTGTGCTTAATCGTCGCGATGAGACGGGAGAATTTATCACTTTGCGCATTCGTTTCGCCTTAAATCGTAGAGATAGTGG
TTTTATTTCTGGGCTGATTGCTGTCTTGCATGATACGACTGAGCAAGAAAAAGAAGACCGTGAACGTCGCTTGTTCGTTT
CTAACGTTAGTCACGAGTTGCGTACGCCACTGACTTCGGTTAAATCTTATCTTGAGGCACTGGATGAAGGAGCTCTGAAA
GAAGATATTGCACCAAGTTTCATTAAAGTTTCTTTGGATGAAACCAACCGTATGATTCGCATGATTTCTGATTTGCTTAA
CTTATCTCGTATTGATAATCAGACAGTGCAGTTAGAAGTTGAAATGACTAACTTCACAGCCTTTATGACGTCTATTTTGA
ATCGTTTTGACCAGATTAAGAGCCAACACACGGTTGCTGGCAAGCAATACGAAATTGTCAGAGACTATCCAATCAAGTCA
ATCTGGGTTGAAATTGACCCAGATAAGATGACACAGGTCTTGGATAATATCCTTAACAATGCGATTAAGTACTCACCAGA
TGGTGGAAAAATCACTGTCAGCATGAAGACAACTGAAACTCAGTTGATTATTTCGATTTCTGATGAAGGACTTGGTATTC
CGAAGAAAGATTTGCCGTTAATCTTTGACCGTTTCTACCGTGTTGATAAGGCTAGAAGTCGTGCCCAAGGTGGTTCAGGG
CTTGGACTTGCCATTGCTAAAGAAATTGTCAAACAACATAAAGGATTTATTTGGGCTCAAAGTACCTATGGTAAGGGCTC
AACATTTACAATTGTTCTTCCGTATGAGAAGGATTCTGATATTTATGATGAATGGGAGGATGACGAGGACTAG

Domains

Predicted by InterproScan.

PAS fold (PAS)

(95-189)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(326-436)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

76.867

92.222

0.709
  micB Streptococcus pneumoniae Cp1015

64.237

97.556

0.627