Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   KO461_RS04290 Genome accession   NZ_CP076449
Coordinates   826154..827377 (-) Length   407 a.a.
NCBI ID   WP_005540455.1    Uniprot ID   Q8KRY4
Organism   Aggregatibacter actinomycetemcomitans strain CU1000N     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 821154..832377
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KO461_RS04265 (KO461_04280) - 821835..823943 (-) 2109 WP_094978696.1 alpha/beta hydrolase -
  KO461_RS04270 - 823966..824142 (-) 177 WP_228414662.1 hypothetical protein -
  KO461_RS04275 - 824151..824729 (-) 579 WP_005566183.1 DUF4123 domain-containing protein -
  KO461_RS04280 - 824733..825299 (-) 567 WP_228414663.1 hypothetical protein -
  KO461_RS04285 (KO461_04295) - 825468..826157 (-) 690 WP_005594882.1 prepilin peptidase -
  KO461_RS04290 (KO461_04300) pilC 826154..827377 (-) 1224 WP_005540455.1 type II secretion system F family protein Machinery gene
  KO461_RS04295 (KO461_04305) - 827370..828779 (-) 1410 Protein_845 GspE/PulE family protein -
  KO461_RS04300 (KO461_04310) pilA 828806..829258 (-) 453 WP_005550263.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  KO461_RS04305 (KO461_04315) ampD 829380..829934 (+) 555 WP_005540460.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  KO461_RS04310 (KO461_04320) nanQ 830408..830878 (-) 471 WP_005540462.1 N-acetylneuraminate anomerase -

Sequence

Protein


Download         Length: 407 a.a.        Molecular weight: 46222.71 Da        Isoelectric Point: 10.3517

>NTDB_id=575426 KO461_RS04290 WP_005540455.1 826154..827377(-) (pilC) [Aggregatibacter actinomycetemcomitans strain CU1000N]
MTKLKLFQWRGVNRLQQKQKGLIVAETEVMAQQQLLSRGLQNIKLQQNWQFSHKPKNADICTLLSQLATLLRAAVPLKNS
LQILLQNCTNIALNRWLRCLLQEIESGLAFSQALEQQGLYLTYQERQLIQVGEMTGKLAAVCHEIAQHKQQALALQRKIQ
KILLYPLLVLGISLILTALLLLFIVPQFAAMYDNSNAQLPVFTQVLLALSQGLQDYWFALLMFIALTVALIRFRLKHSPW
LNRQKNRLINSIPLLNRIVQLSRLVGFSRSLFLMLQAGIPLNQALQSFLPKQQSWQSKPQQQGDWLLITEVQSALHWIQQ
GYPFSASVSGQIFPPAAQQMLQVGEQSGQLPKMLQFIANDHQQQLDHQIDLLSQMLEPLLMVIIGGLIGLIMLGMYLPIF
NMGSLVQ

Nucleotide


Download         Length: 1224 bp        

>NTDB_id=575426 KO461_RS04290 WP_005540455.1 826154..827377(-) (pilC) [Aggregatibacter actinomycetemcomitans strain CU1000N]
ATGACTAAATTGAAACTGTTTCAATGGCGCGGCGTTAATCGCTTGCAGCAAAAACAAAAAGGCTTAATCGTGGCGGAAAC
GGAGGTGATGGCACAACAACAGCTGCTTTCACGTGGGTTGCAAAACATCAAATTGCAACAAAACTGGCAATTCAGCCACA
AACCGAAAAATGCCGATATCTGCACCCTGCTTTCCCAACTGGCGACGCTATTACGAGCCGCCGTGCCGCTGAAAAACAGC
CTGCAAATTTTATTGCAAAATTGTACCAATATTGCGTTGAATCGCTGGCTACGCTGCTTGCTACAGGAGATTGAAAGCGG
CTTGGCATTTTCTCAAGCATTGGAACAACAAGGGTTATACTTAACCTATCAGGAACGCCAACTGATTCAGGTGGGTGAAA
TGACAGGCAAACTTGCCGCCGTCTGTCATGAAATCGCACAACATAAACAACAGGCGCTGGCGTTGCAGCGTAAAATTCAG
AAAATCCTGCTTTATCCGTTGCTGGTGCTCGGAATCTCATTGATTTTGACCGCACTTTTATTGCTGTTCATCGTGCCGCA
ATTTGCCGCCATGTATGACAACAGCAACGCGCAACTGCCCGTGTTCACGCAGGTTTTACTAGCCCTTTCCCAAGGCTTGC
AGGATTATTGGTTCGCGCTACTCATGTTTATTGCGCTGACCGTGGCGTTAATTCGCTTTCGCCTCAAACATTCGCCTTGG
CTTAACCGACAAAAAAACCGGCTGATTAACAGTATTCCGTTGCTTAATCGTATCGTACAACTCTCCCGCCTGGTGGGATT
CAGTCGCAGCTTGTTTTTGATGTTACAGGCAGGTATTCCGCTGAATCAGGCGCTGCAATCTTTTCTACCGAAGCAACAAA
GCTGGCAAAGCAAACCGCAACAGCAAGGGGATTGGCTATTAATTACAGAAGTGCAATCGGCACTGCATTGGATTCAACAA
GGCTATCCGTTCTCCGCCAGCGTAAGCGGACAAATCTTCCCGCCGGCGGCACAGCAAATGCTGCAAGTCGGCGAACAAAG
CGGTCAATTGCCGAAAATGCTGCAATTTATCGCCAACGATCATCAGCAACAGTTGGATCACCAAATCGATCTGCTGTCAC
AAATGCTGGAACCGTTGTTGATGGTGATTATCGGCGGGCTGATCGGCTTGATTATGCTCGGTATGTATTTACCGATTTTC
AACATGGGCTCGCTGGTGCAATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(267-398)

Type II secretion system (T2SS), protein F (T2SSF)

(64-186)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q8KRY4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Haemophilus influenzae Rd KW20

63.145

100

0.631
  pilC Haemophilus influenzae 86-028NP

62.899

100

0.629
  pilC Glaesserella parasuis strain SC1401

39.066

100

0.391