Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   KO461_RS02410 Genome accession   NZ_CP076449
Coordinates   465212..466621 (+) Length   469 a.a.
NCBI ID   WP_005564712.1    Uniprot ID   -
Organism   Aggregatibacter actinomycetemcomitans strain CU1000N     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 460212..471621
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KO461_RS02385 (KO461_02380) - 460239..462806 (-) 2568 WP_005564721.1 penicillin-binding protein 1A -
  KO461_RS02390 (KO461_02385) - 462940..463749 (+) 810 WP_005564718.1 hypothetical protein -
  KO461_RS02395 (KO461_02390) - 463760..464278 (+) 519 WP_005564716.1 PilN domain-containing protein -
  KO461_RS02400 (KO461_02395) - 464275..464799 (+) 525 WP_005543969.1 hypothetical protein -
  KO461_RS02405 (KO461_02400) - 464799..465191 (+) 393 WP_205764648.1 competence protein ComD -
  KO461_RS02410 (KO461_02405) comE 465212..466621 (+) 1410 WP_005564712.1 type IV pilus secretin PilQ Machinery gene
  KO461_RS02415 (KO461_02410) aroK 466835..467362 (+) 528 WP_005543963.1 shikimate kinase AroK -
  KO461_RS02420 (KO461_02415) aroB 467386..468474 (+) 1089 WP_005564710.1 3-dehydroquinate synthase -
  KO461_RS02425 (KO461_02420) - 468477..469331 (+) 855 WP_205764649.1 Dam family site-specific DNA-(adenine-N6)-methyltransferase -
  KO461_RS02430 (KO461_02425) - 469570..470199 (-) 630 WP_231098927.1 ABC transporter six-transmembrane domain-containing protein -
  KO461_RS11380 - 470148..470450 (-) 303 WP_005564706.1 ABC transporter six-transmembrane domain-containing protein -
  KO461_RS02435 (KO461_02430) - 470450..470893 (-) 444 WP_061888258.1 MarR family winged helix-turn-helix transcriptional regulator -

Sequence

Protein


Download         Length: 469 a.a.        Molecular weight: 51776.51 Da        Isoelectric Point: 7.1243

>NTDB_id=575416 KO461_RS02410 WP_005564712.1 465212..466621(+) (comE) [Aggregatibacter actinomycetemcomitans strain CU1000N]
MKSILSRWLKCGLLFGCFLSLTVQAEQNPVFSIRLKQAPLVPTLQQLALAHNTNLIIDDELQGTVSLQLENVDLDQLFRS
VAKIKQLDLWQENGIYYFTKGDTNAKFAGKMEEPFPLSMPMAEEPAQLTTATIKLHFAKASEVMKSLTGGSGSLLSPNGS
ITFDDRSNLLLIQDEPRSVRNIKKLIKELDKPIEQIAIEARIVTINDESLKELGVRWGIFNPTENAHRIGGSLAGNGFDN
LVNQLNVNFPTTTTPAGSVALQVAKINGRLLDLELTALERENNVEIIASPRLLTTNKKSASIKQGTELPYILVNEKSGSQ
SVEFREAVLGLEVTPHISQDKQILLDLIVSQNSPGSRVAYGLGEVVSIDKQEINTQVFAKDGETIVLGGVFSDTITKGTD
KVPVLGDIPGIKHLFSKESERHQKRELVIFVTPHILRKGETPDAFKQKRIGVNEQIMAKGENKKDLNRK

Nucleotide


Download         Length: 1410 bp        

>NTDB_id=575416 KO461_RS02410 WP_005564712.1 465212..466621(+) (comE) [Aggregatibacter actinomycetemcomitans strain CU1000N]
ATGAAATCGATTCTTTCCCGATGGCTAAAGTGCGGTCTGCTTTTCGGGTGTTTTTTAAGTCTTACAGTGCAGGCGGAACA
AAATCCGGTGTTTTCCATTCGGCTGAAACAGGCACCACTGGTTCCGACTTTGCAGCAGTTGGCATTAGCCCACAATACCA
ATTTGATTATTGACGATGAACTGCAAGGCACGGTGTCGTTACAGTTGGAAAACGTGGATTTGGATCAGCTGTTTCGTTCT
GTGGCAAAAATTAAACAACTGGATTTATGGCAGGAAAACGGCATTTATTATTTCACTAAAGGTGACACCAACGCGAAATT
TGCCGGCAAAATGGAAGAGCCTTTTCCTCTTTCAATGCCCATGGCGGAAGAACCGGCACAGCTGACCACGGCGACCATTA
AATTACACTTTGCCAAAGCGTCGGAAGTGATGAAATCCCTCACCGGGGGGAGTGGTTCCCTGTTGTCGCCTAACGGCAGT
ATCACTTTCGACGATCGTAGCAATTTGTTGCTGATTCAGGATGAACCGCGCTCCGTCCGCAACATAAAAAAGCTGATTAA
GGAACTGGATAAACCCATTGAGCAAATCGCCATTGAAGCGCGCATTGTCACCATTAACGATGAAAGCCTGAAAGAACTGG
GCGTGCGCTGGGGGATTTTCAACCCGACGGAAAACGCCCATCGTATTGGTGGCAGTTTGGCGGGCAACGGCTTTGATAAC
CTTGTCAATCAGTTAAACGTAAATTTTCCCACGACCACGACACCGGCAGGCTCTGTGGCGTTACAGGTTGCGAAAATCAA
CGGGCGACTTTTAGACTTAGAATTGACCGCACTTGAACGGGAAAATAATGTGGAAATCATCGCAAGCCCACGCCTGCTAA
CGACAAACAAAAAAAGCGCCAGCATCAAACAGGGGACGGAATTACCCTATATTCTGGTGAACGAAAAAAGCGGTTCGCAA
AGCGTGGAATTTCGTGAGGCGGTACTAGGTTTGGAAGTCACGCCGCACATTTCGCAGGATAAACAAATTCTGTTAGATCT
TATCGTCAGCCAAAACTCGCCGGGCAGCCGTGTGGCATACGGTTTGGGCGAAGTGGTTTCTATTGATAAACAGGAGATTA
ATACACAAGTCTTCGCCAAGGACGGCGAAACCATTGTGCTGGGCGGTGTATTTAGCGATACCATCACCAAAGGCACCGAT
AAAGTGCCGGTGCTGGGTGACATTCCGGGTATTAAACATTTATTCAGCAAGGAAAGTGAACGCCATCAAAAACGCGAGCT
GGTGATTTTTGTCACACCACATATTTTGCGTAAAGGCGAAACCCCGGACGCTTTCAAACAAAAGCGAATCGGGGTAAATG
AGCAAATCATGGCAAAAGGGGAGAATAAAAAGGACCTAAATAGGAAATAA

Domains

Predicted by InterproScan.

Bacterial type II and III secretion system protein (Secretin)

(277-437)

Bacterial type II/III secretion system short domain (Secretin_N)

(130-195)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Haemophilus influenzae Rd KW20

71.875

95.522

0.687
  comE Haemophilus influenzae 86-028NP

70.982

95.522

0.678
  comE Glaesserella parasuis strain SC1401

53.318

93.177

0.497
  pilQ Vibrio campbellii strain DS40M4

41.244

92.537

0.382
  pilQ Vibrio cholerae O1 biovar El Tor strain E7946

41.589

91.258

0.38
  pilQ Vibrio cholerae strain A1552

41.589

91.258

0.38