Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   KIP81_RS08045 Genome accession   NZ_CP075172
Coordinates   1611509..1612201 (-) Length   230 a.a.
NCBI ID   WP_021143010.1    Uniprot ID   A0A239R7J1
Organism   Streptococcus equinus strain SheepZ001     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1606509..1617201
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KIP81_RS08025 (KIP81_08020) dnaI 1607318..1608220 (-) 903 WP_024343628.1 primosomal protein DnaI -
  KIP81_RS08030 (KIP81_08025) - 1608231..1609382 (-) 1152 WP_074566833.1 DnaD domain protein -
  KIP81_RS08035 (KIP81_08030) nrdR 1609369..1609863 (-) 495 WP_004233042.1 transcriptional regulator NrdR -
  KIP81_RS08040 (KIP81_08035) - 1610022..1611404 (-) 1383 WP_243602767.1 ATP-binding protein -
  KIP81_RS08045 (KIP81_08040) covR 1611509..1612201 (-) 693 WP_021143010.1 response regulator transcription factor Regulator
  KIP81_RS08050 (KIP81_08045) - 1612441..1612977 (-) 537 WP_027968408.1 YceD family protein -
  KIP81_RS08055 (KIP81_08050) htpX 1613123..1614022 (-) 900 WP_074483767.1 zinc metalloprotease HtpX -
  KIP81_RS08060 (KIP81_08055) - 1614139..1614690 (-) 552 WP_021143013.1 LemA family protein -
  KIP81_RS08065 (KIP81_08060) rsmG 1614986..1615699 (+) 714 WP_039691523.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  KIP81_RS08070 (KIP81_08065) - 1615765..1617138 (+) 1374 WP_074480237.1 potassium transporter TrkG -

Sequence

Protein


Download         Length: 230 a.a.        Molecular weight: 26437.38 Da        Isoelectric Point: 4.8639

>NTDB_id=568262 KIP81_RS08045 WP_021143010.1 1611509..1612201(-) (covR) [Streptococcus equinus strain SheepZ001]
MSKKILIIEDEKNLARFVSLELQHEGYSVVVETNGRLGLQTALDDDFDLILLDLMLPDMDGFEITRRLRLEKETSIIMMT
ARDSIMDIVAGLDRGADDYIVKPFAIEELLARVRAVFRRQEANSKHDKEGQAKEGLLGLRLNPQNRSAVRGDDEISLTKR
EYDLLSVLLSNVNRVMTREELLASVWRYDTDIETNVVDVYIRYLRGKIDIPGKESYIQTVRGMGYIIREK

Nucleotide


Download         Length: 693 bp        

>NTDB_id=568262 KIP81_RS08045 WP_021143010.1 1611509..1612201(-) (covR) [Streptococcus equinus strain SheepZ001]
ATGAGTAAAAAGATTTTAATTATTGAGGATGAAAAAAATCTTGCACGCTTCGTGTCTTTGGAGTTACAACACGAAGGGTA
TTCAGTAGTTGTTGAGACAAATGGGCGTTTAGGTTTACAAACGGCTTTAGATGATGATTTTGATTTGATCCTGTTGGACT
TGATGTTGCCTGATATGGATGGATTCGAAATTACACGTCGTCTTCGTTTGGAAAAAGAAACTTCAATTATCATGATGACA
GCTCGTGATTCAATCATGGATATCGTTGCTGGTCTTGATCGTGGCGCAGATGATTACATCGTAAAACCATTTGCTATTGA
AGAACTATTAGCGCGTGTGCGTGCAGTGTTCCGTCGTCAGGAAGCTAATTCAAAACATGATAAAGAAGGTCAAGCTAAAG
AGGGGTTGCTTGGGCTTCGTCTTAATCCACAAAATCGTTCTGCAGTTCGTGGAGACGATGAAATTTCATTAACAAAACGC
GAATATGATTTGTTAAGTGTTCTTCTTTCAAACGTTAACCGAGTGATGACACGTGAAGAATTACTTGCAAGTGTTTGGCG
TTATGATACTGATATCGAAACAAACGTAGTGGATGTTTACATCCGTTATCTTCGTGGAAAAATTGATATTCCTGGTAAAG
AATCATATATCCAAACTGTTCGTGGAATGGGTTATATTATTCGAGAAAAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(153-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A239R7J1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

75.217

100

0.752
  covR Lactococcus lactis subsp. lactis strain DGCC12653

65.066

99.565

0.648
  vicR Streptococcus mutans UA159

41.991

100

0.422
  micA Streptococcus pneumoniae Cp1015

41.739

100

0.417