Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   KIP81_RS07250 Genome accession   NZ_CP075172
Coordinates   1457843..1459195 (-) Length   450 a.a.
NCBI ID   WP_024343735.1    Uniprot ID   -
Organism   Streptococcus equinus strain SheepZ001     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1452843..1464195
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KIP81_RS07240 (KIP81_07235) rnc 1456140..1456826 (-) 687 WP_021142842.1 ribonuclease III -
  KIP81_RS07245 (KIP81_07240) vicX 1457033..1457842 (-) 810 WP_243602702.1 MBL fold metallo-hydrolase Regulator
  KIP81_RS07250 (KIP81_07245) vicK 1457843..1459195 (-) 1353 WP_024343735.1 cell wall metabolism sensor histidine kinase VicK Regulator
  KIP81_RS07255 (KIP81_07250) vicR 1459188..1459898 (-) 711 WP_021142846.1 response regulator YycF Regulator
  KIP81_RS07260 (KIP81_07255) - 1460206..1460970 (+) 765 WP_024343734.1 amino acid ABC transporter ATP-binding protein -
  KIP81_RS07265 (KIP81_07260) - 1460981..1461784 (+) 804 WP_243602703.1 transporter substrate-binding domain-containing protein -
  KIP81_RS07270 (KIP81_07265) - 1461800..1462504 (+) 705 WP_004232799.1 amino acid ABC transporter permease -
  KIP81_RS07275 (KIP81_07270) - 1462514..1463161 (+) 648 WP_004232801.1 amino acid ABC transporter permease -
  KIP81_RS07280 (KIP81_07275) - 1463193..1463801 (-) 609 WP_243602704.1 VTT domain-containing protein -

Sequence

Protein


Download         Length: 450 a.a.        Molecular weight: 51391.34 Da        Isoelectric Point: 4.7300

>NTDB_id=568259 KIP81_RS07250 WP_024343735.1 1457843..1459195(-) (vicK) [Streptococcus equinus strain SheepZ001]
MNNIMSQNQYLFEQAILFLLAFVAVYFIHLAIRDYRTSVNIRRLSGKVRELITGKYTEDIIIEKDRDLAELAGQLNDLST
VFRLAQENLAQEKNRLASILSYMTDGVLATDRSGNITMINQTAQQQLNLEREEALGMNIVDILGDDSDYTYHDLVSKTPE
IVLNRRDETGEFITLRIRFALNRRDSGFISGLIAVLHDTTEQEKEDRERRLFVSNVSHELRTPLTSVKSYLEALDEGALK
EDIAPSFIKVSLDETNRMIRMISDLLNLSRIDNQTVQLEVEMTNFTAFMTSILNRFDQIKSQHTVAGKQYEIVRDYPIKS
IWLEIDPDKMTQVLDNILNNAIKYSPDGGKITVSMKTTETQLIISISDEGLGIPKKDLPLIFDRFYRVDKARSRAQGGSG
LGLAIAKEIVKQHKGFIWAQSTYGKGSTFTIVLPYEKDSDIYDEWEDDED

Nucleotide


Download         Length: 1353 bp        

>NTDB_id=568259 KIP81_RS07250 WP_024343735.1 1457843..1459195(-) (vicK) [Streptococcus equinus strain SheepZ001]
ATGAATAATATAATGTCACAGAATCAGTATCTGTTTGAGCAGGCAATCTTGTTTTTGCTCGCTTTTGTCGCTGTTTATTT
TATTCATTTAGCGATAAGAGATTATCGAACTTCAGTTAATATTCGTCGTTTGAGTGGTAAGGTTCGTGAGCTTATCACTG
GTAAATACACTGAAGACATCATTATTGAAAAAGATAGAGATTTGGCTGAACTTGCTGGTCAGTTAAATGACTTGTCAACG
GTTTTTCGCTTAGCTCAGGAAAATCTTGCGCAGGAAAAAAATCGTTTGGCTAGTATTTTGTCTTATATGACTGACGGTGT
CTTGGCTACTGACCGTTCTGGAAATATCACCATGATTAACCAGACAGCTCAGCAGCAACTTAATCTTGAACGCGAAGAAG
CTCTTGGAATGAATATTGTTGATATTCTTGGGGACGATAGCGATTATACCTACCATGATTTGGTTTCTAAGACACCTGAG
ATTGTTCTAAATCGTCGTGATGAGACAGGTGAATTTATCACTTTGCGAATTCGTTTTGCGCTGAATCGTCGTGATAGTGG
CTTTATCTCAGGGTTGATTGCTGTTTTACATGATACAACGGAACAAGAAAAGGAAGACCGAGAACGTCGTTTATTCGTAT
CAAATGTTAGTCACGAATTGCGTACACCGTTGACATCTGTGAAATCATATTTGGAAGCTTTGGATGAAGGTGCACTTAAA
GAAGATATTGCACCAAGTTTTATTAAAGTTTCTCTTGATGAAACAAACCGTATGATTCGAATGATTTCTGATTTGCTCAA
TTTGTCTCGAATTGATAATCAGACTGTTCAGCTTGAAGTTGAAATGACTAACTTTACAGCATTTATGACATCAATTTTGA
ACCGTTTTGACCAAATTAAGAGTCAACATACAGTCGCTGGTAAGCAGTATGAGATTGTCAGAGATTATCCAATCAAGTCT
ATCTGGTTAGAAATTGACCCAGATAAAATGACGCAAGTTCTGGATAATATCCTTAATAATGCAATTAAGTATTCGCCAGA
TGGTGGTAAAATCACTGTCAGCATGAAGACGACTGAGACACAGTTGATTATTTCAATTTCTGATGAAGGTCTTGGTATTC
CTAAGAAAGATTTGCCGCTAATCTTTGACCGATTCTATCGTGTTGACAAGGCTAGAAGTCGTGCTCAAGGTGGTTCAGGA
CTTGGTCTTGCGATTGCAAAAGAAATTGTTAAACAACACAAAGGATTTATTTGGGCTCAAAGTACTTATGGAAAAGGCTC
AACCTTTACAATTGTTCTTCCGTATGAGAAGGATTCTGATATTTATGACGAATGGGAGGATGACGAGGACTAG

Domains

Predicted by InterproScan.

PAS fold (PAS)

(95-189)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(326-436)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

76.867

92.222

0.709
  micB Streptococcus pneumoniae Cp1015

66.038

94.222

0.622