Detailed information NTG0056588

Bioinformatically predicted

Overview

• Name: comD/blpH
• Type: Regulator
• Locus tag: SITYG_RS10535
• Genome accession: NZ_AP014880
• Coordinates: 618972..619595 (-)
• Length: 207 a.a.
• NCBI ID: WP_231870255.1
• Uniprot ID: -
• Organism: Streptococcus intermedius strain TYG1620
• Function: phosphorylation of ComE; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 613972..624595

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SITYG_RS03185 (SITYG_06130)	-	614304..614678 (-)	375	WP_003073369.1	hypothetical protein	-
SITYG_RS03195 (SITYG_06140)	comA/nlmT	615159..617309 (+)	2151	WP_096362643.1	peptide cleavage/export ABC transporter	Regulator
SITYG_RS03200 (SITYG_06150)	-	617320..618681 (+)	1362	WP_096362644.1	bacteriocin secretion accessory protein	-
SITYG_RS03205 (SITYG_06160)	-	618778..618927 (+)	150	WP_096362645.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
SITYG_RS10535 (SITYG_06170)	comD/blpH	618972..619595 (-)	624	WP_231870255.1	sensor histidine kinase	Regulator
SITYG_RS10540 (SITYG_06180)	-	619617..620288 (-)	672	WP_231870256.1	hypothetical protein	-
SITYG_RS03215 (SITYG_06190)	comE/blpR	620290..621036 (-)	747	WP_041787711.1	response regulator transcription factor	Regulator
SITYG_RS03220 (SITYG_06200)	-	621205..621918 (-)	714	WP_096362646.1	CPBP family intramembrane glutamic endopeptidase	-
SITYG_RS03225 (SITYG_06210)	-	622150..622374 (+)	225	WP_003025424.1	Blp family class II bacteriocin	-
SITYG_RS03230 (SITYG_06220)	-	622462..622782 (+)	321	WP_003037422.1	hypothetical protein	-
SITYG_RS03235 (SITYG_06230)	-	622790..623011 (+)	222	WP_003025422.1	Blp family class II bacteriocin	-
SITYG_RS03240 (SITYG_06240)	-	623252..623479 (+)	228	WP_096362647.1	bacteriocin class II family protein	-
SITYG_RS03245 (SITYG_06250)	-	623515..623835 (+)	321	WP_096362648.1	hypothetical protein	-
SITYG_RS03250 (SITYG_06260)	-	624065..624280 (+)	216	WP_009568291.1	bacteriocin class II family protein	-

Sequence

Protein

• Length: 207 a.a.
• Molecular weight: 23307.47 Da
• Isoelectric Point: 5.8225

>NTDB_id=56588 SITYG_RS10535 WP_231870255.1 618972..619595(-) (comD/blpH) [Streptococcus intermedius strain TYG1620]
MENYSHHIEELYTEVRSFRHDYANILTTLKLGIEQNDIGIVKNVYHSVLKDSNKRFRNPKYDIGRLVHIKNDALKSLLAA
KFAQAQEHNVSVSLEVPEDICPQGMELVDFITIVSILCDNAIEAAAPTMTIAYVLSENKQVFSIENSIKEEHIDMSYIFD
AGVSSKGSGRGIGLSNVLAILDRYPSVSLASTSQNYRFQHVLEIYLN

Nucleotide

• Length: 624 bp

>NTDB_id=56588 SITYG_RS10535 WP_231870255.1 618972..619595(-) (comD/blpH) [Streptococcus intermedius strain TYG1620]
TTGGAAAACTATAGTCATCACATTGAGGAATTGTACACAGAAGTTCGGAGCTTTCGGCATGATTACGCTAATATTTTAAC
AACCTTGAAATTAGGAATTGAGCAAAATGATATAGGCATTGTAAAGAATGTTTATCATTCTGTTTTGAAAGATTCCAATA
AGCGTTTTCGCAATCCCAAGTATGATATTGGACGGTTAGTCCATATCAAAAACGATGCCTTAAAAAGCCTGCTAGCTGCT
AAATTTGCACAAGCTCAAGAGCATAATGTATCCGTTTCATTGGAAGTTCCAGAAGATATTTGTCCACAAGGAATGGAATT
AGTTGACTTTATCACCATTGTCTCCATTTTGTGTGATAATGCGATTGAAGCTGCCGCTCCAACTATGACGATTGCTTATG
TTTTGTCAGAAAACAAGCAGGTATTCTCCATTGAAAATTCTATAAAAGAAGAGCATATAGACATGTCTTATATTTTTGAT
GCGGGAGTTAGTTCTAAAGGATCTGGGCGAGGAATTGGATTATCAAATGTCTTAGCAATTCTGGATCGATATCCAAGTGT
TTCACTTGCGAGTACTAGTCAAAATTATCGTTTCCAGCATGTCCTTGAAATTTATCTGAATTAA

Domains

Predicted by InterProScan.

• GHKL domain (HATPase_c_5) (105-200)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comD/blpH	Streptococcus mutans UA159	46.154	100	0.464
comD/comD1	Streptococcus equinus JB1	46.341	99.034	0.459
comD/comD3	Streptococcus equinus JB1	44.498	100	0.449
comD/comD2	Streptococcus equinus JB1	42.105	100	0.425