Detailed information
Bioinformatically predicted
Overview
| Name | pilU | Type | Machinery gene |
| Locus tag | KIH05_RS04980 | Genome accession | NZ_CP074585 |
| Coordinates | 1031224..1032342 (-) | Length | 372 a.a. |
| NCBI ID | WP_000347036.1 | Uniprot ID | A0A009PAD6 |
| Organism | Acinetobacter baumannii strain ATCC 19606 | ||
| Function | mediate the depolymerization of the type IV pilus (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 995765..1062917 | 1031224..1032342 | within | 0 |
Gene organization within MGE regions
Location: 995765..1062917
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| KIH05_RS04805 (KIH05_04795) | - | 996166..996726 (-) | 561 | WP_001048354.1 | hypothetical protein | - |
| KIH05_RS04810 (KIH05_04800) | - | 996817..997677 (-) | 861 | WP_000838088.1 | pirin family protein | - |
| KIH05_RS04815 (KIH05_04805) | hemJ | 997848..998300 (-) | 453 | WP_000339889.1 | protoporphyrinogen oxidase HemJ | - |
| KIH05_RS04820 (KIH05_04810) | - | 998319..999548 (-) | 1230 | WP_000832710.1 | beta-ketoacyl-ACP synthase II | - |
| KIH05_RS04825 (KIH05_04815) | - | 999845..1001170 (+) | 1326 | WP_000160010.1 | EcsC family protein | - |
| KIH05_RS04830 (KIH05_04820) | rpsL | 1001371..1001745 (+) | 375 | WP_000246374.1 | 30S ribosomal protein S12 | - |
| KIH05_RS04835 (KIH05_04825) | rpsG | 1001905..1002375 (+) | 471 | WP_001138055.1 | 30S ribosomal protein S7 | - |
| KIH05_RS04840 (KIH05_04830) | fusA | 1002554..1004692 (+) | 2139 | WP_000113824.1 | elongation factor G | - |
| KIH05_RS04845 (KIH05_04835) | tuf | 1004787..1005977 (+) | 1191 | WP_001029610.1 | elongation factor Tu | - |
| KIH05_RS04850 (KIH05_04840) | - | 1006181..1007062 (+) | 882 | WP_000992301.1 | metal-dependent hydrolase | - |
| KIH05_RS04855 (KIH05_04845) | - | 1007299..1008174 (+) | 876 | WP_000992291.1 | metal-dependent hydrolase | - |
| KIH05_RS04860 (KIH05_04850) | rimI | 1008282..1008737 (+) | 456 | WP_000621546.1 | ribosomal protein S18-alanine N-acetyltransferase | - |
| KIH05_RS04865 (KIH05_04855) | - | 1008782..1009597 (-) | 816 | WP_000844343.1 | arginyltransferase | - |
| KIH05_RS04870 (KIH05_04860) | aat | 1009616..1010347 (-) | 732 | WP_000854789.1 | leucyl/phenylalanyl-tRNA--protein transferase | - |
| KIH05_RS04875 (KIH05_04865) | trxB | 1010468..1011415 (-) | 948 | WP_001276144.1 | thioredoxin-disulfide reductase | - |
| KIH05_RS04880 (KIH05_04870) | - | 1011685..1014717 (+) | 3033 | WP_000127835.1 | DNA translocase FtsK | - |
| KIH05_RS04885 (KIH05_04875) | rhtC | 1014866..1015486 (+) | 621 | WP_000959259.1 | threonine export protein RhtC | - |
| KIH05_RS04890 (KIH05_04880) | - | 1015529..1015816 (-) | 288 | WP_001218560.1 | PA4642 family protein | - |
| KIH05_RS04895 (KIH05_04885) | minE | 1015900..1016172 (-) | 273 | WP_000896934.1 | cell division topological specificity factor MinE | - |
| KIH05_RS04900 (KIH05_04890) | minD | 1016175..1016987 (-) | 813 | WP_001074362.1 | septum site-determining protein MinD | - |
| KIH05_RS04905 (KIH05_04895) | minC | 1017058..1017780 (-) | 723 | WP_000763677.1 | septum site-determining protein MinC | - |
| KIH05_RS04910 (KIH05_04900) | - | 1017902..1018948 (-) | 1047 | WP_001181637.1 | hypothetical protein | - |
| KIH05_RS04915 (KIH05_04905) | - | 1018965..1019891 (-) | 927 | WP_000100975.1 | acyltransferase | - |
| KIH05_RS04920 (KIH05_04910) | - | 1020136..1020789 (+) | 654 | WP_001202415.1 | OmpA family protein | - |
| KIH05_RS04925 (KIH05_04915) | rep | 1020983..1023022 (+) | 2040 | WP_000093035.1 | DNA helicase Rep | - |
| KIH05_RS04930 (KIH05_04920) | dut | 1023048..1023500 (+) | 453 | WP_000868152.1 | dUTP diphosphatase | - |
| KIH05_RS04935 (KIH05_04925) | - | 1023700..1025118 (+) | 1419 | WP_001102833.1 | phosphomannomutase/phosphoglucomutase | - |
| KIH05_RS04940 (KIH05_04930) | argB | 1025133..1026041 (+) | 909 | WP_001135419.1 | acetylglutamate kinase | - |
| KIH05_RS04945 (KIH05_04935) | - | 1026162..1026944 (+) | 783 | WP_000890283.1 | GNAT family N-acetyltransferase | - |
| KIH05_RS04950 (KIH05_04940) | - | 1027053..1027901 (+) | 849 | WP_000336554.1 | class II glutamine amidotransferase | - |
| KIH05_RS04955 (KIH05_04945) | - | 1028154..1028609 (+) | 456 | WP_000782976.1 | bacteriohemerythrin | - |
| KIH05_RS04960 (KIH05_04950) | - | 1028762..1029829 (+) | 1068 | WP_005144332.1 | hypothetical protein | - |
| KIH05_RS04965 (KIH05_04955) | - | 1029829..1030152 (+) | 324 | WP_000442584.1 | RnfH family protein | - |
| KIH05_RS04970 (KIH05_04960) | - | 1030207..1030605 (-) | 399 | WP_001170994.1 | outer membrane protein assembly factor BamE | - |
| KIH05_RS04975 (KIH05_04965) | fur | 1030717..1031154 (+) | 438 | WP_001122847.1 | ferric iron uptake transcriptional regulator | - |
| KIH05_RS04980 (KIH05_04970) | pilU | 1031224..1032342 (-) | 1119 | WP_000347036.1 | PilT/PilU family type 4a pilus ATPase | Machinery gene |
| KIH05_RS04985 (KIH05_04975) | pilT | 1032370..1033407 (-) | 1038 | WP_000355489.1 | type IV pilus twitching motility protein PilT | Machinery gene |
| KIH05_RS04990 (KIH05_04980) | - | 1033534..1034226 (+) | 693 | WP_001108520.1 | YggS family pyridoxal phosphate-dependent enzyme | - |
| KIH05_RS04995 (KIH05_04985) | - | 1034427..1038023 (-) | 3597 | WP_000698801.1 | AAA family ATPase | - |
| KIH05_RS05000 (KIH05_04990) | - | 1038033..1039301 (-) | 1269 | WP_001984248.1 | exonuclease SbcCD subunit D | - |
| KIH05_RS05005 (KIH05_04995) | - | 1039466..1039939 (+) | 474 | WP_002134289.1 | OsmC family protein | - |
| KIH05_RS05010 (KIH05_05000) | - | 1040013..1040390 (-) | 378 | WP_001059437.1 | VOC family protein | - |
| KIH05_RS05015 (KIH05_05005) | - | 1040770..1041222 (+) | 453 | WP_000164154.1 | ABZJ_00895 family protein | - |
| KIH05_RS05020 (KIH05_05010) | - | 1041311..1042216 (+) | 906 | WP_001039359.1 | TIGR01777 family oxidoreductase | - |
| KIH05_RS05025 (KIH05_05015) | - | 1042208..1043323 (-) | 1116 | WP_000546700.1 | NAD(P)/FAD-dependent oxidoreductase | - |
| KIH05_RS05030 (KIH05_05020) | hemB | 1043349..1044362 (-) | 1014 | WP_000222569.1 | porphobilinogen synthase | - |
| KIH05_RS05035 (KIH05_05025) | - | 1044505..1045002 (+) | 498 | WP_002019577.1 | thioesterase family protein | - |
| KIH05_RS05040 (KIH05_05030) | - | 1045272..1046423 (+) | 1152 | WP_000128703.1 | EmrA/EmrK family multidrug efflux transporter periplasmic adaptor subunit | - |
| KIH05_RS05045 (KIH05_05035) | - | 1046430..1047953 (+) | 1524 | WP_000857095.1 | DHA2 family efflux MFS transporter permease subunit | - |
| KIH05_RS05050 (KIH05_05040) | ggt | 1048257..1050242 (+) | 1986 | WP_001042928.1 | gamma-glutamyltransferase | - |
| KIH05_RS05060 (KIH05_05050) | - | 1050943..1052172 (+) | 1230 | WP_002134292.1 | tyrosine-type recombinase/integrase | - |
| KIH05_RS05065 (KIH05_05055) | - | 1052322..1052948 (+) | 627 | WP_000151565.1 | hypothetical protein | - |
| KIH05_RS05070 (KIH05_05060) | - | 1053076..1053291 (+) | 216 | WP_000153154.1 | hypothetical protein | - |
| KIH05_RS05075 (KIH05_05065) | - | 1053294..1053503 (+) | 210 | WP_001016479.1 | helix-turn-helix domain-containing protein | - |
| KIH05_RS05080 (KIH05_05070) | - | 1053500..1054054 (+) | 555 | WP_000991775.1 | Bro-N domain-containing protein | - |
| KIH05_RS05085 (KIH05_05075) | - | 1054047..1054415 (+) | 369 | WP_001046480.1 | hypothetical protein | - |
| KIH05_RS05090 (KIH05_05080) | - | 1054425..1054736 (+) | 312 | WP_000787400.1 | hypothetical protein | - |
| KIH05_RS05095 (KIH05_05085) | - | 1054851..1055129 (+) | 279 | WP_001064706.1 | hypothetical protein | - |
| KIH05_RS05100 (KIH05_05090) | - | 1055141..1057606 (+) | 2466 | WP_001022433.1 | DUF927 domain-containing protein | - |
| KIH05_RS05105 (KIH05_05095) | - | 1057930..1058133 (+) | 204 | WP_001984265.1 | single-stranded DNA-binding protein | - |
| KIH05_RS05110 (KIH05_05100) | - | 1058270..1059712 (+) | 1443 | WP_000003532.1 | hypothetical protein | - |
| KIH05_RS05115 (KIH05_05105) | - | 1060055..1060729 (+) | 675 | WP_000560650.1 | DUF3800 domain-containing protein | - |
| KIH05_RS05120 (KIH05_05110) | - | 1060729..1060917 (+) | 189 | WP_000642900.1 | hypothetical protein | - |
| KIH05_RS05125 (KIH05_05115) | - | 1061062..1061637 (+) | 576 | WP_000067109.1 | hypothetical protein | - |
Sequence
Protein
Download Length: 372 a.a. Molecular weight: 41905.11 Da Isoelectric Point: 6.6944
>NTDB_id=565482 KIH05_RS04980 WP_000347036.1 1031224..1032342(-) (pilU) [Acinetobacter baumannii strain ATCC 19606]
MDFNDLLNLMVEKKSSDLFITDGVAPSMKINGQIVPISKNSLSGEVIGQLLHSIMSEKQRKEFAETRECNFAIMNREKTA
RFRVSAFQQRDMPGMVLRRIETKIPSIDDLQLPPVLKDLSMTKRGIIIFVGATGTGKSTSLASMISHRNHNSKGHIITIE
DPIEFIHEHAGCIITQREVGIDTDSFEIALKNTLRQAPDVILIGEIRSREVMDYAIGFAETGHLVLATMHANNANQALDR
IIHFFESDRHSQLYMDLSLNLKAMIAQQLIPTPDGNSRRAAIEILINSPLISDYIRKGEIHEIKDLMKRSRELGMQTFDQ
ALFDLYKAGQITYKDALKHADSPNDLRLTIKLADEGPDQLSDGKQHLTFDRQ
MDFNDLLNLMVEKKSSDLFITDGVAPSMKINGQIVPISKNSLSGEVIGQLLHSIMSEKQRKEFAETRECNFAIMNREKTA
RFRVSAFQQRDMPGMVLRRIETKIPSIDDLQLPPVLKDLSMTKRGIIIFVGATGTGKSTSLASMISHRNHNSKGHIITIE
DPIEFIHEHAGCIITQREVGIDTDSFEIALKNTLRQAPDVILIGEIRSREVMDYAIGFAETGHLVLATMHANNANQALDR
IIHFFESDRHSQLYMDLSLNLKAMIAQQLIPTPDGNSRRAAIEILINSPLISDYIRKGEIHEIKDLMKRSRELGMQTFDQ
ALFDLYKAGQITYKDALKHADSPNDLRLTIKLADEGPDQLSDGKQHLTFDRQ
Nucleotide
Download Length: 1119 bp
>NTDB_id=565482 KIH05_RS04980 WP_000347036.1 1031224..1032342(-) (pilU) [Acinetobacter baumannii strain ATCC 19606]
ATGGATTTTAATGACTTGCTCAACCTGATGGTTGAAAAAAAATCTTCCGATCTCTTTATTACAGATGGCGTTGCGCCCTC
TATGAAGATTAACGGGCAAATTGTTCCAATTTCAAAAAATAGTCTTTCAGGCGAAGTAATTGGTCAACTATTACATTCCA
TCATGAGTGAAAAACAACGCAAAGAATTTGCAGAAACTCGTGAATGTAACTTTGCCATTATGAACCGTGAAAAAACGGCG
CGTTTTCGTGTCAGTGCTTTTCAGCAGCGCGACATGCCGGGCATGGTACTACGTCGTATTGAAACCAAGATTCCTTCAAT
TGATGACTTGCAGTTACCGCCTGTACTTAAAGATTTATCGATGACCAAACGCGGCATTATTATTTTCGTAGGCGCGACAG
GTACAGGTAAATCCACTTCATTGGCTTCAATGATCAGCCATCGTAACCATAACTCTAAGGGCCATATCATTACCATTGAA
GACCCGATTGAGTTTATTCACGAACATGCAGGTTGCATCATTACTCAGCGTGAAGTCGGGATCGATACCGACTCATTTGA
AATTGCCTTGAAAAATACACTACGACAAGCGCCGGATGTGATCTTAATTGGTGAGATCCGTTCTCGTGAAGTCATGGACT
ACGCGATTGGCTTTGCTGAAACAGGCCATCTTGTATTAGCTACCATGCACGCCAACAACGCCAACCAAGCGCTCGACCGT
ATTATTCACTTTTTTGAAAGTGACCGTCATAGTCAGCTTTACATGGACTTGTCACTTAACTTAAAGGCAATGATTGCGCA
GCAGCTCATTCCAACACCAGATGGTAATTCACGCCGTGCAGCAATTGAGATTTTAATTAACTCACCATTAATTTCAGACT
ACATCCGTAAAGGTGAAATTCATGAAATTAAAGATTTGATGAAACGCTCACGTGAACTTGGTATGCAGACCTTTGACCAA
GCTTTATTTGATTTATATAAAGCTGGTCAAATTACCTACAAAGATGCACTTAAACATGCTGACTCACCGAACGATTTACG
TTTAACCATTAAACTTGCTGATGAAGGTCCTGATCAATTATCAGACGGGAAACAGCATTTAACTTTTGACCGCCAGTAA
ATGGATTTTAATGACTTGCTCAACCTGATGGTTGAAAAAAAATCTTCCGATCTCTTTATTACAGATGGCGTTGCGCCCTC
TATGAAGATTAACGGGCAAATTGTTCCAATTTCAAAAAATAGTCTTTCAGGCGAAGTAATTGGTCAACTATTACATTCCA
TCATGAGTGAAAAACAACGCAAAGAATTTGCAGAAACTCGTGAATGTAACTTTGCCATTATGAACCGTGAAAAAACGGCG
CGTTTTCGTGTCAGTGCTTTTCAGCAGCGCGACATGCCGGGCATGGTACTACGTCGTATTGAAACCAAGATTCCTTCAAT
TGATGACTTGCAGTTACCGCCTGTACTTAAAGATTTATCGATGACCAAACGCGGCATTATTATTTTCGTAGGCGCGACAG
GTACAGGTAAATCCACTTCATTGGCTTCAATGATCAGCCATCGTAACCATAACTCTAAGGGCCATATCATTACCATTGAA
GACCCGATTGAGTTTATTCACGAACATGCAGGTTGCATCATTACTCAGCGTGAAGTCGGGATCGATACCGACTCATTTGA
AATTGCCTTGAAAAATACACTACGACAAGCGCCGGATGTGATCTTAATTGGTGAGATCCGTTCTCGTGAAGTCATGGACT
ACGCGATTGGCTTTGCTGAAACAGGCCATCTTGTATTAGCTACCATGCACGCCAACAACGCCAACCAAGCGCTCGACCGT
ATTATTCACTTTTTTGAAAGTGACCGTCATAGTCAGCTTTACATGGACTTGTCACTTAACTTAAAGGCAATGATTGCGCA
GCAGCTCATTCCAACACCAGATGGTAATTCACGCCGTGCAGCAATTGAGATTTTAATTAACTCACCATTAATTTCAGACT
ACATCCGTAAAGGTGAAATTCATGAAATTAAAGATTTGATGAAACGCTCACGTGAACTTGGTATGCAGACCTTTGACCAA
GCTTTATTTGATTTATATAAAGCTGGTCAAATTACCTACAAAGATGCACTTAAACATGCTGACTCACCGAACGATTTACG
TTTAACCATTAAACTTGCTGATGAAGGTCCTGATCAATTATCAGACGGGAAACAGCATTTAACTTTTGACCGCCAGTAA
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| pilU | Acinetobacter baylyi ADP1 |
75.926 |
100 |
0.772 |
| pilU | Pseudomonas stutzeri DSM 10701 |
69.293 |
98.925 |
0.685 |
| pilU | Vibrio cholerae strain A1552 |
53.243 |
99.462 |
0.53 |
| pilT | Deinococcus radiodurans R1 = ATCC 13939 = DSM 20539 |
42.197 |
93.011 |
0.392 |