Detailed information    

insolico Bioinformatically predicted

Overview

Name   comS   Type   Regulator
Locus tag   - Genome accession   HE613569
Coordinates   110367..110411 (+) Length   15 a.a.
NCBI ID   - Uniprot ID   -
Organism   Streptococcus macedonicus ACA-DC 198     
Function   activate transcription of comX; activate transcription of comS (predicted from homology)   
Competence regulation

Genomic Context

Location: 105367..115411
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMA_0100 ackA 106320..107519 (+) 1200 CCF01391.1 Acetate kinase -
  SMA_0101 - 107681..107881 (+) 201 CCF01392.1 Transcriptional regulator, Cro/CI family -
  SMA_0102 - 107891..108100 (+) 210 CCF01393.1 Hypothetical protein -
  SMA_0103 - 108113..108565 (+) 453 CCF01394.1 Hypothetical protein -
  SMA_0104 - 108577..109212 (+) 636 CCF01395.1 Membrane-bound protease, CAAX family -
  SMA_0105 comR 109391..110290 (+) 900 CCF01396.1 Transcriptional regulator Regulator
  - comS 110367..110411 (+) 45 - - Regulator
  SMA_0106 purD 110764..112026 (+) 1263 CCF01397.1 Phosphoribosylamine--glycine ligase -
  SMA_0107 ybbK 112016..112465 (+) 450 CCF01398.1 Hypothetical protein -
  SMA_0108 purE 112465..112953 (+) 489 CCF01399.1 Phosphoribosylaminoimidazole carboxylase catalytic subunit -
  SMA_0109 purK 112940..114031 (+) 1092 CCF01400.1 Phosphoribosylaminoimidazole carboxylase ATPase subunit -
  SMA_0110 - 114051..114329 (+) 279 CCF01401.1 Hypothetical protein -

Sequence

Protein


Download         Length: 15 a.a.        Molecular weight: 1798.22 Da        Isoelectric Point: 9.1500

>NTDB_id=564 110367..110411(+) (comS) [Streptococcus macedonicus ACA-DC 198]
MLKFFSIVITGWWGL

Nucleotide


Download         Length: 45 bp        

>NTDB_id=564 110367..110411(+) (comS) [Streptococcus macedonicus ACA-DC 198]
ATGCTAAAATTTTTTTCAATTGTTATAACTGGTTGGTGGGGATTA

XIP

This gene is known to encode the precursor of σX inducing peptide (XIP), which involves in competence development. The mature XIP sequence is displayed as below:

ITGWWGL


Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comS Streptococcus infantarius subsp. infantarius ATCC BAA-102

60

100

0.6
  djlA Legionella pneumophila str. Paris

72.727

73.333

0.533
  djlA Legionella pneumophila strain ERS1305867

72.727

73.333

0.533

Multiple sequence alignment