Detailed information    

insolico Bioinformatically predicted

Overview

Name   comW   Type   Regulator
Locus tag   L3475_RS00275 Genome accession   NZ_CP091451
Coordinates   40162..40398 (+) Length   78 a.a.
NCBI ID   WP_000939544.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 3238/09     
Function   stabilization and activation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 35162..45398
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L3475_RS00265 (L3475_00260) - 38855..39064 (+) 210 Protein_46 transposase -
  L3475_RS00270 (L3475_00265) - 39099..39896 (-) 798 Protein_47 transposase -
  L3475_RS00275 (L3475_00270) comW 40162..40398 (+) 237 WP_000939544.1 sigma(X)-activator ComW Regulator
  L3475_RS00280 (L3475_00275) - 40629..41915 (+) 1287 WP_000205044.1 adenylosuccinate synthase -
  L3475_RS00285 (L3475_00280) tadA 42116..42583 (+) 468 WP_000291879.1 tRNA adenosine(34) deaminase TadA -
  L3475_RS00295 (L3475_00290) - 42770..43213 (+) 444 WP_000701992.1 dUTP diphosphatase -
  L3475_RS00300 (L3475_00295) - 43215..43730 (+) 516 WP_000691236.1 histidine phosphatase family protein -
  L3475_RS00305 (L3475_00300) radA 43744..45105 (+) 1362 WP_073076903.1 DNA repair protein RadA Machinery gene

Sequence

Protein


Download         Length: 78 a.a.        Molecular weight: 9667.10 Da        Isoelectric Point: 6.4701

>NTDB_id=561479 L3475_RS00275 WP_000939544.1 40162..40398(+) (comW) [Streptococcus pneumoniae strain 3238/09]
MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVRYGIGCHRDFIVYHYRVAYRLYLEKLVMNRGFISC

Nucleotide


Download         Length: 237 bp        

>NTDB_id=561479 L3475_RS00275 WP_000939544.1 40162..40398(+) (comW) [Streptococcus pneumoniae strain 3238/09]
ATGTTACAAAAAATTTATGAGCAGATGGCTAATTTCTATGATAGTATTGAAGAAGAGTATGGTCCTACATTTGGTGATAA
TTTTGACTGGGAACATGTTCATTTTAAATTTTTAATTTATTATTTAGTGAGATATGGCATTGGTTGTCATAGGGATTTTA
TCGTTTACCATTATCGTGTTGCTTATCGTTTGTATCTTGAAAAATTGGTAATGAATCGGGGTTTTATTTCTTGTTGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comW Streptococcus pneumoniae Rx1

97.436

100

0.974
  comW Streptococcus pneumoniae D39

97.436

100

0.974
  comW Streptococcus pneumoniae R6

97.436

100

0.974
  comW Streptococcus pneumoniae TIGR4

97.436

100

0.974
  comW Streptococcus mitis SK321

78.205

100

0.782
  comW Streptococcus mitis NCTC 12261

77.922

98.718

0.769