Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   L2Z46_RS17275 Genome accession   NZ_CP091373
Coordinates   3573471..3574145 (+) Length   224 a.a.
NCBI ID   WP_000161505.1    Uniprot ID   A0A0D5YFC9
Organism   Acinetobacter baumannii strain AB21-VUB     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 3568471..3579145
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L2Z46_RS17255 (L2Z46_17255) tnpB 3569236..3569571 (-) 336 WP_000618092.1 IS66 family insertion sequence element accessory protein TnpB -
  L2Z46_RS17260 (L2Z46_17260) - 3569568..3569951 (-) 384 WP_001055585.1 transposase -
  L2Z46_RS17265 (L2Z46_17265) - 3570322..3571626 (+) 1305 WP_000362916.1 DcaP family trimeric outer membrane transporter -
  L2Z46_RS17270 (L2Z46_17270) - 3571807..3573456 (+) 1650 WP_031994270.1 phosphoethanolamine--lipid A transferase -
  L2Z46_RS17275 (L2Z46_17275) ciaR 3573471..3574145 (+) 675 WP_000161505.1 response regulator transcription factor Regulator
  L2Z46_RS17280 (L2Z46_17280) - 3574171..3575505 (+) 1335 WP_000559381.1 two-component system sensor histidine kinase PmrB -
  L2Z46_RS17285 (L2Z46_17285) - 3575506..3576204 (-) 699 WP_000184466.1 phosphatase PAP2 family protein -
  L2Z46_RS17290 (L2Z46_17290) - 3576357..3577544 (-) 1188 WP_002001094.1 ammonium transporter -
  L2Z46_RS17295 (L2Z46_17295) - 3577847..3578731 (-) 885 WP_000144743.1 LysR family transcriptional regulator -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25548.47 Da        Isoelectric Point: 5.3246

>NTDB_id=560918 L2Z46_RS17275 WP_000161505.1 3573471..3574145(+) (ciaR) [Acinetobacter baumannii strain AB21-VUB]
MTKILMIEDDFMIAESTITLLQYHQFEVEWVNNGLDGLAQLAKTKFDLILLDLGLPMMDGMQVLKQIRQRAATPVLIISA
RDQLQNRVDGLNLGADDYLIKPYEFDELLARIHALLRRSGVEAQLASQDQLLESGDLVLNVEQHIATFKGQRIDLSNREW
AILIPLMTHPNKIFSKANLEDKLYDFDSDVTSNTIEVYVHHLRAKLGKDFIRTIRGLGYRLGQS

Nucleotide


Download         Length: 675 bp        

>NTDB_id=560918 L2Z46_RS17275 WP_000161505.1 3573471..3574145(+) (ciaR) [Acinetobacter baumannii strain AB21-VUB]
ATGACAAAAATCTTGATGATTGAAGATGATTTTATGATTGCAGAATCAACGATCACGTTGCTGCAATATCATCAATTTGA
GGTGGAATGGGTCAATAACGGTTTAGATGGTTTGGCTCAATTGGCGAAGACTAAATTTGATCTTATTCTTTTGGATTTAG
GATTGCCTATGATGGATGGTATGCAAGTTTTGAAGCAGATCCGTCAAAGAGCAGCAACACCAGTATTAATTATTTCTGCT
CGAGATCAATTACAAAACCGTGTCGATGGTTTAAATTTGGGTGCAGATGATTATTTAATTAAACCTTATGAATTTGATGA
GTTGCTTGCCCGTATTCATGCATTACTACGCCGTAGTGGAGTAGAAGCTCAACTTGCGAGTCAAGATCAACTATTAGAAA
GTGGCGATCTGGTTTTAAATGTTGAACAGCATATTGCGACGTTTAAAGGTCAACGCATTGATCTATCAAATCGTGAATGG
GCAATCTTAATTCCACTTATGACTCACCCAAATAAAATCTTTTCTAAAGCCAACTTAGAAGATAAGTTATATGATTTTGA
TAGTGATGTGACCAGTAATACTATTGAAGTATATGTTCACCATTTAAGAGCGAAGCTGGGTAAAGATTTTATTCGAACCA
TCCGAGGACTGGGCTACCGTTTGGGGCAATCATAA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(150-221)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  PDB 9OF3
  PDB 9OF4
  PDB 9OF5
  PDB 9OF6
  PDB 9OF7
  PDB 9OF8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

38.496

100

0.388
  ciaR Streptococcus pneumoniae D39

38.496

100

0.388
  ciaR Streptococcus pneumoniae R6

38.496

100

0.388
  ciaR Streptococcus pneumoniae TIGR4

38.496

100

0.388
  ciaR Streptococcus mutans UA159

37.445

100

0.379
  micA Streptococcus pneumoniae Cp1015

35.965

100

0.366