Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   L2Z35_RS19180 Genome accession   NZ_CP091341
Coordinates   3970315..3970989 (-) Length   224 a.a.
NCBI ID   WP_000161505.1    Uniprot ID   A0A0D5YFC9
Organism   Acinetobacter baumannii strain AB226-VUB     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 3965315..3975989
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L2Z35_RS19160 (L2Z35_19160) - 3965729..3966613 (+) 885 WP_000144729.1 LysR family transcriptional regulator -
  L2Z35_RS19165 (L2Z35_19165) - 3966916..3968103 (+) 1188 WP_002001094.1 ammonium transporter -
  L2Z35_RS19170 (L2Z35_19170) - 3968256..3968954 (+) 699 WP_000184466.1 phosphatase PAP2 family protein -
  L2Z35_RS19175 (L2Z35_19175) - 3968955..3970289 (-) 1335 WP_025367730.1 two-component system sensor histidine kinase PmrB -
  L2Z35_RS19180 (L2Z35_19180) ciaR 3970315..3970989 (-) 675 WP_000161505.1 response regulator transcription factor Regulator
  L2Z35_RS19185 (L2Z35_19185) - 3971004..3972653 (-) 1650 WP_002017062.1 phosphoethanolamine--lipid A transferase -
  L2Z35_RS19190 (L2Z35_19190) - 3972837..3974141 (-) 1305 WP_000362914.1 DcaP family trimeric outer membrane transporter -
  L2Z35_RS19195 (L2Z35_19195) - 3974687..3975934 (-) 1248 WP_000489706.1 MFS transporter -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25548.47 Da        Isoelectric Point: 5.3246

>NTDB_id=559059 L2Z35_RS19180 WP_000161505.1 3970315..3970989(-) (ciaR) [Acinetobacter baumannii strain AB226-VUB]
MTKILMIEDDFMIAESTITLLQYHQFEVEWVNNGLDGLAQLAKTKFDLILLDLGLPMMDGMQVLKQIRQRAATPVLIISA
RDQLQNRVDGLNLGADDYLIKPYEFDELLARIHALLRRSGVEAQLASQDQLLESGDLVLNVEQHIATFKGQRIDLSNREW
AILIPLMTHPNKIFSKANLEDKLYDFDSDVTSNTIEVYVHHLRAKLGKDFIRTIRGLGYRLGQS

Nucleotide


Download         Length: 675 bp        

>NTDB_id=559059 L2Z35_RS19180 WP_000161505.1 3970315..3970989(-) (ciaR) [Acinetobacter baumannii strain AB226-VUB]
ATGACAAAAATCTTGATGATTGAAGATGATTTTATGATTGCAGAATCAACGATCACGTTGCTGCAATATCATCAATTTGA
GGTGGAATGGGTCAATAACGGTTTAGATGGTTTGGCTCAGTTGGCGAAGACTAAATTTGATCTTATTCTTTTGGATTTAG
GATTGCCTATGATGGATGGTATGCAAGTTTTAAAGCAGATCCGTCAAAGAGCAGCAACACCAGTATTAATTATTTCTGCT
CGAGATCAATTACAAAACCGTGTCGATGGTTTAAATTTGGGTGCAGATGATTATTTAATTAAACCTTATGAGTTTGATGA
GTTGCTTGCCCGTATTCATGCATTACTACGCCGTAGTGGAGTAGAAGCTCAACTTGCGAGTCAAGATCAACTATTAGAAA
GTGGTGATCTGGTTTTAAATGTTGAACAGCATATTGCGACGTTTAAAGGCCAACGCATTGATTTATCAAATCGTGAATGG
GCAATCTTAATTCCACTTATGACTCACCCAAATAAAATCTTTTCTAAAGCCAACTTAGAAGATAAGTTATATGATTTTGA
TAGTGATGTGACCAGTAATACTATTGAAGTATATGTTCACCATTTAAGAGCGAAGCTGGGTAAAGATTTTATTCGAACCA
TCCGAGGACTGGGCTACCGTTTGGGGCAATCATAA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(150-221)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  PDB 9OF3
  PDB 9OF4
  PDB 9OF5
  PDB 9OF6
  PDB 9OF7
  PDB 9OF8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

38.496

100

0.388
  ciaR Streptococcus pneumoniae D39

38.496

100

0.388
  ciaR Streptococcus pneumoniae R6

38.496

100

0.388
  ciaR Streptococcus pneumoniae TIGR4

38.496

100

0.388
  ciaR Streptococcus mutans UA159

37.445

100

0.379
  micA Streptococcus pneumoniae Cp1015

35.965

100

0.366