Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   KCL43_RS08840 Genome accession   NZ_CP073275
Coordinates   1835494..1836180 (-) Length   228 a.a.
NCBI ID   WP_012516253.1    Uniprot ID   U5Y8A0
Organism   Streptococcus equi subsp. zooepidemicus strain IN-6992     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1830494..1841180
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KCL43_RS08820 (KCL43_08820) dnaI 1831259..1832167 (-) 909 WP_165623222.1 primosomal protein DnaI -
  KCL43_RS08825 (KCL43_08825) - 1832168..1833331 (-) 1164 WP_206157605.1 helicase loader -
  KCL43_RS08830 (KCL43_08830) nrdR 1833315..1833809 (-) 495 WP_012516251.1 transcriptional regulator NrdR -
  KCL43_RS08835 (KCL43_08835) - 1834000..1835490 (-) 1491 WP_012516252.1 HAMP domain-containing histidine kinase -
  KCL43_RS08840 (KCL43_08840) covR 1835494..1836180 (-) 687 WP_012516253.1 two-component system response regulator CovR Regulator
  KCL43_RS08845 (KCL43_08845) - 1836365..1836898 (-) 534 WP_042671270.1 YceD family protein -
  KCL43_RS08850 (KCL43_08850) htpX 1837186..1838079 (-) 894 WP_014623438.1 zinc metalloprotease HtpX -
  KCL43_RS08855 (KCL43_08855) - 1838111..1838668 (-) 558 WP_012677410.1 LemA family protein -
  KCL43_RS08860 (KCL43_08860) rsmG 1838805..1839518 (+) 714 WP_012516257.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 26580.56 Da        Isoelectric Point: 4.6541

>NTDB_id=558797 KCL43_RS08840 WP_012516253.1 1835494..1836180(-) (covR) [Streptococcus equi subsp. zooepidemicus strain IN-6992]
MTKKILIIEDEKNLARFVSLELQHEGYEVTVEVNGREGLETALEKDFDLILLDLMLPEMDGFEVTRRLQTEKTTYIMMMT
ARDSIMDVVAGLDRGADDYIVKPFAIEELLARIRAIFRRQDIESEKKTPSQGVYRDLVLNPQNRSVNRGDDEISLTKREY
DLLNILMTNMNRVMTREELLSNVWKYDEAVETNVVDVYIRYLRGKIDIPGKESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 687 bp        

>NTDB_id=558797 KCL43_RS08840 WP_012516253.1 1835494..1836180(-) (covR) [Streptococcus equi subsp. zooepidemicus strain IN-6992]
ATGACAAAGAAAATTTTAATTATCGAAGATGAAAAGAATCTTGCAAGATTTGTTTCGCTTGAGCTACAACATGAGGGTTA
CGAGGTGACCGTCGAGGTTAATGGTCGTGAGGGCTTGGAGACAGCCCTAGAGAAGGACTTTGACTTAATCCTTCTTGATT
TGATGCTTCCTGAGATGGACGGATTTGAAGTGACACGTCGCTTGCAAACAGAAAAAACGACTTACATCATGATGATGACT
GCGCGTGACTCTATTATGGACGTTGTAGCTGGCTTGGATCGTGGTGCTGACGATTACATCGTGAAGCCATTTGCCATTGA
GGAATTGCTGGCGCGTATTCGTGCTATCTTCCGTCGTCAGGACATTGAGTCAGAGAAAAAGACTCCTAGTCAAGGCGTTT
ACCGCGACTTAGTCTTAAACCCTCAAAACCGCTCTGTCAATCGCGGTGATGACGAGATTTCACTGACTAAGCGTGAATAT
GACCTGCTTAATATTTTGATGACAAACATGAATCGTGTCATGACTCGTGAGGAGCTCTTGTCTAACGTTTGGAAATATGA
CGAGGCTGTTGAAACTAACGTTGTTGATGTTTATATTCGTTACCTTCGTGGGAAGATCGATATCCCTGGGAAAGAGTCTT
ACATTCAAACTGTTCGTGGAATGGGTTATGTGATTCGCGAGAAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(151-224)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB U5Y8A0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

82.533

100

0.829
  covR Lactococcus lactis subsp. lactis strain DGCC12653

67.401

99.561

0.671
  vicR Streptococcus mutans UA159

43.29

100

0.439
  micA Streptococcus pneumoniae Cp1015

42.174

100

0.425