Detailed information NTG0558778

Bioinformatically predicted

Overview

• Name: comE/blpR
• Type: Regulator
• Locus tag: KCL43_RS04990
• Genome accession: NZ_CP073275
• Coordinates: 1045124..1045861 (+)
• Length: 245 a.a.
• NCBI ID: WP_165623379.1
• Uniprot ID: -
• Organism: Streptococcus equi subsp. zooepidemicus strain IN-6992
• Function: activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1040124..1050861

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KCL43_RS04960 (KCL43_04960)	-	1040566..1041471 (-)	906	WP_165623378.1	diacylglycerol/lipid kinase family protein	-
KCL43_RS04965 (KCL43_04965)	trhA	1041581..1042231 (-)	651	WP_012515586.1	PAQR family membrane homeostasis protein TrhA	-
KCL43_RS04970 (KCL43_04970)	-	1042215..1042670 (-)	456	WP_043983552.1	DUF1836 domain-containing protein	-
KCL43_RS04975 (KCL43_04975)	-	1042930..1043685 (+)	756	WP_138119296.1	class I SAM-dependent methyltransferase	-
KCL43_RS04980 (KCL43_04980)	-	1043713..1044051 (+)	339	WP_021320756.1	cupin domain-containing protein	-
KCL43_RS04985 (KCL43_04985)	-	1044053..1044358 (+)	306	WP_021320757.1	AraC family ligand binding domain-containing protein	-
KCL43_RS04990 (KCL43_04990)	comE/blpR	1045124..1045861 (+)	738	WP_165623379.1	response regulator transcription factor	Regulator
KCL43_RS04995 (KCL43_04995)	-	1046234..1046434 (+)	201	WP_042670621.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
KCL43_RS05000 (KCL43_05000)	-	1046501..1047355 (+)	855	WP_165623388.1	ABC transporter ATP-binding protein	-
KCL43_RS05005 (KCL43_05005)	-	1047361..1048524 (+)	1164	WP_042670623.1	ABC transporter permease subunit	-
KCL43_RS05010 (KCL43_05010)	-	1048786..1049016 (+)	231	WP_012515596.1	Blp family class II bacteriocin	-
KCL43_RS05015 (KCL43_05015)	-	1049892..1050173 (+)	282	WP_012515598.1	lactococcin 972 family bacteriocin	-

Sequence

Protein

• Length: 245 a.a.
• Molecular weight: 28935.34 Da
• Isoelectric Point: 8.2668

>NTDB_id=558778 KCL43_RS04990 WP_165623379.1 1045124..1045861(+) (comE/blpR) [Streptococcus equi subsp. zooepidemicus strain IN-6992]
MNIFILEDDLGQQFRLEMKIQEILDKHHWTCDRFEVYGKPYQLLANVTERGRHQLFFLDIQIRNDEKKGLAVAREIRKRD
PYALIVFVTTHSELMPVSFRYQVSALDFIDKELSMKHFSDRIERAIRYAYEEQENVTSEGLFIFATAKAQVQVPFSSLLF
IETSSTPHKLILHSQNERIEFYGFLSEVLKQDSRLVQCHRSYVINPYNVSFLDRDKRLLYFKNGQSCMVSRLKMKALEAS
IKALH

Nucleotide

• Length: 738 bp

>NTDB_id=558778 KCL43_RS04990 WP_165623379.1 1045124..1045861(+) (comE/blpR) [Streptococcus equi subsp. zooepidemicus strain IN-6992]
ATGAATATTTTTATTCTCGAAGATGATCTAGGCCAACAGTTTAGGCTTGAGATGAAGATTCAAGAGATATTGGATAAGCA
TCACTGGACGTGTGATCGTTTTGAAGTTTATGGAAAGCCCTACCAGCTTCTGGCAAATGTTACAGAGAGAGGCAGGCATC
AGCTTTTCTTTCTCGATATTCAAATTCGAAATGATGAGAAAAAGGGCTTAGCTGTTGCTCGTGAGATCAGAAAGCGTGAC
CCTTATGCTCTCATTGTTTTTGTCACGACACATTCTGAGCTTATGCCAGTTTCTTTTCGTTATCAGGTGTCTGCTCTAGA
TTTTATCGATAAGGAATTATCAATGAAACATTTCTCAGATAGGATTGAAAGAGCCATTAGGTATGCTTATGAAGAACAAG
AAAATGTAACCTCAGAGGGCTTATTTATTTTTGCAACGGCTAAGGCTCAGGTGCAGGTTCCTTTTTCAAGCCTATTGTTT
ATTGAGACCTCTAGTACCCCTCACAAGTTGATTTTGCATTCTCAAAACGAGCGAATAGAATTTTATGGCTTTCTTTCAGA
GGTTCTTAAGCAAGATTCCAGACTAGTCCAATGTCATCGTTCTTATGTTATCAATCCTTACAATGTTTCGTTTCTTGATC
GTGATAAGCGTTTACTCTATTTCAAGAATGGGCAGTCTTGCATGGTTTCAAGACTAAAAATGAAAGCACTTGAGGCGTCT
ATTAAGGCTTTGCATTGA

Domains

Predicted by InterproScan.

• LytTr DNA-binding domain (LytTR) (151-240)

• Response regulator receiver domain (Response_reg) (18-122)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/blpR	Streptococcus mutans UA159	54.132	98.776	0.535
comE/comE1	Streptococcus equinus JB1	45.455	98.776	0.449
comE/comE2	Streptococcus equinus JB1	37.295	99.592	0.371