Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   L1704_RS02435 Genome accession   NZ_CP091107
Coordinates   420535..421977 (-) Length   480 a.a.
NCBI ID   WP_058225839.1    Uniprot ID   -
Organism   Lactococcus lactis subsp. lactis strain UC109     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 415535..426977
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L1704_RS02410 (L1704_02410) - 415567..416907 (+) 1341 WP_014570381.1 FAD-dependent oxidoreductase -
  L1704_RS02415 (L1704_02415) - 416997..417386 (+) 390 WP_010905314.1 single-stranded DNA-binding protein -
  L1704_RS02420 (L1704_02420) groES 417506..417790 (+) 285 WP_003131589.1 co-chaperone GroES -
  L1704_RS02425 (L1704_02425) groL 417878..419506 (+) 1629 WP_003131585.1 chaperonin GroEL -
  L1704_RS02430 (L1704_02430) vicX 419552..420364 (-) 813 WP_003131583.1 MBL fold metallo-hydrolase Regulator
  L1704_RS02435 (L1704_02435) vicK 420535..421977 (-) 1443 WP_058225839.1 cell wall metabolism sensor histidine kinase WalK Regulator
  L1704_RS02440 (L1704_02440) yycF 421970..422671 (-) 702 WP_003131580.1 response regulator YycF -
  L1704_RS02445 (L1704_02445) tmk 422849..423484 (+) 636 WP_003131575.1 dTMP kinase -
  L1704_RS02450 (L1704_02450) - 423617..424477 (+) 861 WP_003131573.1 DNA polymerase III subunit delta' -
  L1704_RS02455 (L1704_02455) yaaT 424529..425311 (+) 783 WP_003131572.1 stage 0 sporulation family protein Regulator
  L1704_RS02460 (L1704_02460) yabA 425304..425630 (+) 327 WP_003131570.1 DNA replication initiation control protein YabA -
  L1704_RS02465 (L1704_02465) rsmI 425630..426505 (+) 876 WP_058225840.1 16S rRNA (cytidine(1402)-2'-O)-methyltransferase -
  L1704_RS02470 (L1704_02470) - 426582..426773 (-) 192 WP_058225841.1 hypothetical protein -

Sequence

Protein


Download         Length: 480 a.a.        Molecular weight: 54753.22 Da        Isoelectric Point: 4.5889

>NTDB_id=558102 L1704_RS02435 WP_058225839.1 420535..421977(-) (vicK) [Lactococcus lactis subsp. lactis strain UC109]
MIKFFNSMIFKGVVAHLLLFVILFMSSFDYNFAHLSTFIGYYLFSLVFVLVFLNQQHRMIMNVSKQINDIKNGYLNRDKI
PKGTSEINELYDEILKLGEDIVRTQNNLENQRNQLDSILAYMVDGVIATDRRGNIIMANKSALHYLNTDNDLLMQKNIVE
VLKITDQYNFYDLLEKEPEITIETHDSGNESISLHIKFSLFRRESGFISGIIAVLHDMTEQDKAERERRLFVSNVSHELR
TPLTSVKAYLEALEDGVIEDKETASSFINVSLTETNRMIRMISDLLTLSRMDQDRIVLNKEMINLIAFLDYQINRLDQIL
ETESNDLISSNFTLVRKYSEQPIWVEIDTDKIAQVIDNIIGNAIKYSPKGGTITISVEKRESDVLISISDQGMGIPKSDL
LKIFDRFYRVDNASRNSKVGGTGLGLSIVHDIVKIHGGTIFASSEGEGKGTTFSFTLPYSLEAADDWDDGTDEFEFEDNE

Nucleotide


Download         Length: 1443 bp        

>NTDB_id=558102 L1704_RS02435 WP_058225839.1 420535..421977(-) (vicK) [Lactococcus lactis subsp. lactis strain UC109]
ATGATTAAATTTTTTAATTCAATGATTTTTAAAGGAGTAGTTGCACACCTACTTCTTTTTGTCATCCTTTTTATGAGCAG
TTTTGATTACAATTTTGCTCATTTAAGTACTTTTATTGGTTATTACTTATTTTCACTCGTCTTTGTTTTAGTCTTTCTCA
ATCAGCAACATCGCATGATTATGAATGTTTCTAAACAGATAAATGACATAAAAAATGGCTATTTAAATCGCGATAAAATC
CCAAAAGGGACGAGTGAAATCAATGAATTATATGATGAAATTTTAAAACTTGGTGAAGATATTGTTCGCACGCAGAACAA
TCTTGAAAATCAGCGTAATCAATTAGATAGTATTCTCGCATATATGGTTGATGGCGTCATTGCCACCGATCGTCGTGGAA
ATATTATTATGGCCAATAAATCAGCTTTGCACTATTTGAATACAGATAATGATCTCTTGATGCAAAAAAATATTGTTGAA
GTTTTAAAAATTACTGACCAATATAATTTTTATGATTTATTAGAAAAAGAACCTGAAATAACTATTGAGACACATGATTC
TGGGAATGAATCCATTTCGCTCCACATTAAATTTTCCCTCTTTCGTCGTGAATCTGGTTTCATCTCAGGAATTATTGCCG
TCTTACATGATATGACTGAACAAGACAAGGCCGAACGAGAGCGCCGTCTCTTTGTTTCCAATGTTTCTCATGAACTCCGA
ACTCCGCTCACCTCAGTAAAAGCCTACTTGGAAGCACTAGAAGACGGAGTCATTGAGGATAAAGAAACAGCTTCATCCTT
TATTAATGTTTCACTTACTGAAACTAATCGGATGATTCGAATGATTTCCGACCTTTTGACTTTATCAAGAATGGATCAAG
ACCGAATCGTTCTTAATAAAGAAATGATTAATTTAATTGCCTTCTTAGACTATCAAATTAACCGTTTAGACCAAATTTTA
GAAACCGAATCAAACGATTTAATCTCTTCTAATTTCACTCTAGTCAGAAAATACTCTGAACAGCCCATCTGGGTCGAAAT
TGATACCGATAAAATTGCTCAAGTCATTGACAATATCATCGGAAATGCAATTAAGTATTCACCTAAAGGTGGAACTATTA
CAATTTCCGTTGAAAAACGTGAAAGTGATGTTCTAATCTCCATCAGTGACCAAGGAATGGGGATTCCAAAATCTGATTTA
CTTAAGATTTTTGACCGTTTCTACCGAGTTGATAATGCTTCAAGAAATTCAAAAGTTGGGGGGACAGGTTTAGGCCTCTC
TATTGTCCATGATATTGTTAAAATACATGGCGGAACAATTTTTGCAAGTTCTGAAGGAGAAGGAAAAGGAACGACCTTTA
GTTTCACTCTTCCATATTCTTTAGAAGCCGCAGATGACTGGGATGATGGCACTGATGAGTTTGAATTTGAGGATAATGAA
TAA

Domains

Predicted by InterProScan.

PAS domain (PAS_9)

(124-220)

His Kinase A (phospho-acceptor) domain (HisKA)

(228-293)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(348-459)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

51.079

86.875

0.444
  micB Streptococcus pneumoniae Cp1015

47.297

92.5

0.437