Detailed information NTG0558051

Bioinformatically predicted

Overview

• Name: comP
• Type: Machinery gene
• Locus tag: KCG54_RS10145
• Genome accession: NZ_CP073115
• Coordinates: 2111530..2112024 (-)
• Length: 164 a.a.
• NCBI ID: WP_254324105.1
• Uniprot ID: A0A9X9N0Z5
• Organism: Neisseria subflava strain TT0077
• Function: DNA binding; DNA uptake; receptor of DNA uptake sequence (DUS) (predicted from homology) DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
Genomic island	2095302..2112497	2111530..2112024	within	0

Gene organization within MGE regions

Location: 2095302..2112497

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KCG54_RS10085 (KCG54_10110)	-	2095302..2095724 (-)	423	WP_254324098.1	hypothetical protein	-
KCG54_RS10090 (KCG54_10115)	-	2095766..2097940 (-)	2175	WP_254324099.1	type VI secretion system Vgr family protein	-
KCG54_RS10095 (KCG54_10120)	tssH	2098086..2100902 (-)	2817	WP_254324100.1	type VI secretion system ATPase TssH	-
KCG54_RS10100 (KCG54_10125)	-	2100974..2101462 (-)	489	WP_049332188.1	Hcp family type VI secretion system effector	-
KCG54_RS10105 (KCG54_10130)	-	2101533..2103161 (-)	1629	WP_254324101.1	OmpA family protein	-
KCG54_RS10110 (KCG54_10135)	-	2103179..2103841 (-)	663	WP_101756361.1	DotU/TssL family secretion system protein	-
KCG54_RS10115 (KCG54_10140)	tssK	2103843..2105189 (-)	1347	WP_254324102.1	type VI secretion system baseplate subunit TssK	-
KCG54_RS10120 (KCG54_10145)	tssB	2105349..2105849 (+)	501	WP_049332195.1	type VI secretion system contractile sheath small subunit	-
KCG54_RS10125 (KCG54_10150)	tssC	2105888..2107423 (+)	1536	WP_128580714.1	type VI secretion system contractile sheath large subunit	-
KCG54_RS10130 (KCG54_10155)	-	2107476..2107739 (-)	264	WP_049332348.1	PAAR domain-containing protein	-
KCG54_RS10135 (KCG54_10160)	-	2107786..2108931 (-)	1146	WP_254324103.1	hypothetical protein	-
KCG54_RS10140 (KCG54_10165)	uvrB	2109281..2111308 (-)	2028	WP_254324104.1	excinuclease ABC subunit UvrB	-
KCG54_RS10145 (KCG54_10170)	comP	2111530..2112024 (-)	495	WP_254324105.1	type IV pilin protein	Machinery gene
KCG54_RS10150 (KCG54_10175)	comE	2112210..2112497 (-)	288	WP_036472233.1	helix-hairpin-helix domain-containing protein	Machinery gene

Sequence

Protein

• Length: 164 a.a.
• Molecular weight: 18233.35 Da
• Isoelectric Point: 10.1969

>NTDB_id=558051 KCG54_RS10145 WP_254324105.1 2111530..2112024(-) (comP) [Neisseria subflava strain TT0077]
MYLKAFDRKRDRATVQRGYSLIQLLVVMLLVSILATAAFTVYRESVRSANLRAAHAALLENARFMEQFYTKKGSFKLTST
KWPELPVKEAGGFCIRMSGQAKGILEGKFTLKAVALDREAEPRVLRLNESLTAVVCGKMKGKGSCTDGEEIFRGNDAECK
PFMG

Nucleotide

• Length: 495 bp

>NTDB_id=558051 KCG54_RS10145 WP_254324105.1 2111530..2112024(-) (comP) [Neisseria subflava strain TT0077]
ATGTACTTAAAAGCATTTGACAGAAAACGGGATAGGGCAACTGTGCAGAGGGGCTACTCCTTGATACAGCTGCTGGTGGT
GATGCTGCTGGTTTCGATCTTGGCGACGGCGGCCTTTACGGTCTATCGGGAATCGGTCCGCTCGGCCAACCTGCGTGCGG
CTCATGCCGCACTGCTGGAAAATGCGCGCTTTATGGAGCAGTTCTATACGAAAAAGGGCAGCTTTAAGCTGACGTCGACG
AAGTGGCCGGAATTGCCGGTGAAGGAGGCGGGCGGTTTCTGTATCAGGATGAGCGGCCAGGCTAAGGGTATCCTGGAGGG
TAAGTTTACCTTGAAGGCGGTGGCGCTGGACAGGGAGGCGGAGCCGAGGGTGCTGCGCTTGAATGAGTCGCTGACGGCGG
TGGTGTGCGGGAAGATGAAGGGGAAGGGCAGTTGTACGGACGGTGAGGAGATATTTAGGGGCAATGATGCGGAGTGTAAG
CCTTTTATGGGGTGA

Domains

Predicted by InterproScan.

• Type IV minor pilin ComP, DNA uptake sequence receptor (ComP_DUS) (42-120)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comP	Neisseria subflava NJ9703	97.561	100	0.976
comP	Neisseria meningitidis 8013	50.336	90.854	0.457
comP	Neisseria gonorrhoeae MS11	50.34	89.634	0.451