Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   INT76_RS02165 Genome accession   NZ_CP073084
Coordinates   448739..450127 (-) Length   462 a.a.
NCBI ID   WP_212571701.1    Uniprot ID   -
Organism   Streptococcus oriscaviae strain HKU75     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 443739..455127
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  INT76_RS02140 (INT76_02140) - 444101..445378 (-) 1278 WP_212571693.1 pyrimidine-nucleoside phosphorylase -
  INT76_RS02145 (INT76_02145) - 445375..445965 (-) 591 WP_212571695.1 class I SAM-dependent methyltransferase -
  INT76_RS02150 (INT76_02150) coaA 446040..446963 (+) 924 WP_212571697.1 type I pantothenate kinase -
  INT76_RS02155 (INT76_02155) rpsT 447021..447269 (+) 249 WP_212572993.1 30S ribosomal protein S20 -
  INT76_RS02160 (INT76_02160) - 447384..448628 (-) 1245 WP_212571699.1 transglutaminase domain-containing protein -
  INT76_RS02165 (INT76_02165) ciaH 448739..450127 (-) 1389 WP_212571701.1 HAMP domain-containing sensor histidine kinase Regulator
  INT76_RS02170 (INT76_02170) ciaR 450117..450791 (-) 675 WP_212571703.1 response regulator transcription factor Regulator
  INT76_RS02175 (INT76_02175) - 450845..451249 (-) 405 WP_212571705.1 hypothetical protein -
  INT76_RS11135 (INT76_02180) - 451599..452510 (-) 912 WP_212571707.1 LPXTG cell wall anchor domain-containing protein -
  INT76_RS02185 (INT76_02185) - 452549..453808 (-) 1260 WP_212571708.1 hypothetical protein -
  INT76_RS02190 (INT76_02190) phoU 454130..454786 (-) 657 WP_212571710.1 phosphate signaling complex protein PhoU -

Sequence

Protein


Download         Length: 462 a.a.        Molecular weight: 52784.12 Da        Isoelectric Point: 5.2697

>NTDB_id=557821 INT76_RS02165 WP_212571701.1 448739..450127(-) (ciaH) [Streptococcus oriscaviae strain HKU75]
MLNKFRKLYRTDNFAYFIRYFAVFTLIFGFMTMIIFQLMRATMYQNTDDTFHKIYQDPTTAIQFAIARSYAPGSEIVLEK
GEVTEETPPSTTGSTTEESMSQPQQGQKVGSKIRLSTNFHVVIYDSKGQVFNPDQFSSLSDLKLDKDELESIKEVTVETP
FGGQEDYRYMTIELTSEDLGEYASLDIKYAVIYSNVSQIKSSIASYESTVALVMISFWLISIVASIYLANVSMRPLLVSF
QKQKDFVENASHELRTPLAVLQNRLESLFRHPEATIMESSENIASSLEEVRNMRLLTTSLLNLARRDDGLKPEISDIPPS
FFDEVFANYAIMAEENGKELQVNNEVKQSIRTDRVLLKQLMTILFDNALKYSDEDGQIHIDSRIKDRYLVFTIADNGLGI
RAEDKKKIFDRFYRVDKARTRQKGGFGLGLSLAKQIIDTLDGSIQIRDNHPKGTIFEVRLPR

Nucleotide


Download         Length: 1389 bp        

>NTDB_id=557821 INT76_RS02165 WP_212571701.1 448739..450127(-) (ciaH) [Streptococcus oriscaviae strain HKU75]
ATGTTGAATAAATTTAGAAAGCTCTATCGTACGGATAATTTTGCATATTTTATCCGTTATTTTGCTGTTTTTACCCTCAT
TTTTGGCTTCATGACCATGATTATCTTTCAGCTCATGAGGGCTACCATGTATCAAAATACAGATGATACGTTCCATAAAA
TCTATCAGGATCCTACCACGGCGATTCAGTTTGCCATTGCTAGAAGTTATGCCCCTGGGAGCGAGATTGTTTTAGAAAAG
GGAGAAGTAACAGAAGAAACACCCCCTTCTACGACAGGCTCAACCACTGAAGAGAGTATGAGCCAGCCTCAGCAAGGTCA
AAAAGTCGGTTCAAAAATACGTTTGAGCACCAACTTTCATGTGGTTATCTACGATAGCAAGGGGCAGGTCTTTAACCCGG
ATCAATTCTCCAGCCTATCCGATTTGAAGTTGGACAAGGATGAGCTGGAAAGTATAAAGGAGGTCACAGTGGAAACTCCA
TTTGGTGGCCAAGAAGATTATCGTTATATGACGATTGAGCTGACCAGTGAAGATTTGGGAGAATACGCTTCTCTGGACAT
CAAATACGCTGTCATTTACTCCAATGTCAGTCAAATCAAGTCCTCCATTGCTTCTTACGAGTCAACGGTGGCACTGGTCA
TGATATCCTTCTGGTTGATTTCCATCGTAGCTAGTATTTATCTGGCAAATGTCAGCATGCGTCCACTCTTAGTTAGTTTT
CAGAAGCAAAAAGACTTTGTGGAAAATGCCAGTCACGAATTGCGCACACCGCTAGCTGTTCTGCAAAATCGTCTGGAGAG
CTTGTTCCGTCATCCTGAAGCGACCATCATGGAAAGCAGCGAGAATATCGCCTCCAGTCTGGAAGAAGTCCGCAACATGC
GCCTGCTCACAACGAGCCTGCTCAATTTGGCTCGGCGTGATGATGGCCTGAAACCGGAAATTTCAGATATTCCACCAAGT
TTTTTTGATGAGGTGTTTGCAAACTATGCCATTATGGCTGAAGAAAACGGAAAAGAATTGCAGGTAAACAATGAAGTCAA
GCAGTCCATTCGGACGGATCGCGTGCTTCTCAAACAGTTGATGACCATCCTGTTTGACAATGCCCTCAAATATTCTGATG
AAGATGGACAGATTCATATTGACAGTAGAATTAAGGACCGCTACCTAGTCTTTACTATCGCTGATAATGGCCTAGGAATC
CGAGCAGAAGATAAGAAAAAAATCTTTGATCGCTTTTATCGGGTGGACAAGGCCCGGACTCGGCAGAAGGGGGGATTTGG
TTTGGGGCTTTCTTTGGCCAAGCAGATCATTGACACCTTAGATGGCAGCATTCAGATTCGAGACAATCATCCTAAGGGAA
CTATTTTTGAGGTCAGACTCCCAAGATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(243-309)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(353-461)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

51.193

99.784

0.511
  ciaH Streptococcus pneumoniae D39

51.193

99.784

0.511
  ciaH Streptococcus pneumoniae R6

51.193

99.784

0.511
  ciaH Streptococcus pneumoniae TIGR4

51.193

99.784

0.511
  ciaH Streptococcus mutans UA159

49.024

99.784

0.489