Detailed information NTG0557601

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: KCG41_RS09450
• Genome accession: NZ_CP073065
• Coordinates: 1934716..1935759 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain 17Gst354
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1929716..1940759

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KCG41_RS09420 (KCG41_09425)	-	1930137..1931393 (-)	1257	WP_074347694.1	aminopeptidase	-
KCG41_RS09425 (KCG41_09430)	-	1931396..1931596 (-)	201	WP_000180460.1	DUF1128 family protein	-
KCG41_RS09430 (KCG41_09435)	-	1931743..1932207 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
KCG41_RS09435 (KCG41_09440)	-	1932214..1932489 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
KCG41_RS09440 (KCG41_09445)	-	1932767..1933984 (+)	1218	WP_000037081.1	YihY/virulence factor BrkB family protein	-
KCG41_RS09445 (KCG41_09450)	vraR	1934097..1934726 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
KCG41_RS09450 (KCG41_09455)	vraS	1934716..1935759 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
KCG41_RS09455 (KCG41_09460)	liaF	1935756..1936457 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
KCG41_RS09460 (KCG41_09465)	-	1936472..1936858 (-)	387	WP_001110182.1	hypothetical protein	-
KCG41_RS09465 (KCG41_09470)	map	1937075..1937833 (-)	759	WP_000636145.1	type I methionyl aminopeptidase	-
KCG41_RS09470 (KCG41_09475)	-	1938417..1939403 (+)	987	WP_000999712.1	aromatic acid exporter family protein	-
KCG41_RS09475 (KCG41_09480)	-	1939592..1940005 (-)	414	WP_025174370.1	hypothetical protein	-
KCG41_RS09480 (KCG41_09485)	-	1940034..1940144 (-)	111	WP_014937049.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=557601 KCG41_RS09450 WP_001017131.1 1934716..1935759(-) (vraS) [Staphylococcus aureus strain 17Gst354]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=557601 KCG41_RS09450 WP_001017131.1 1934716..1935759(-) (vraS) [Staphylococcus aureus strain 17Gst354]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTTCTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAATTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAATTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGCTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1