Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   L1O96_RS03605 Genome accession   NZ_CP091016
Coordinates   738220..738879 (-) Length   219 a.a.
NCBI ID   WP_001221491.1    Uniprot ID   -
Organism   Escherichia coli strain STEC306     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 733220..743879
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L1O96_RS03580 - 733424..734176 (-) 753 WP_000619462.1 GntR family transcriptional regulator -
  L1O96_RS03585 - 734463..735794 (+) 1332 Protein_702 MFS transporter -
  L1O96_RS03590 ygiN 735838..736152 (-) 315 WP_000958598.1 putative quinol monooxygenase -
  L1O96_RS03595 mdaB 736183..736764 (-) 582 WP_000065430.1 NADPH:quinone oxidoreductase MdaB -
  L1O96_RS03600 qseC 736874..738223 (-) 1350 WP_000673406.1 quorum sensing histidine kinase QseC -
  L1O96_RS03605 ciaR 738220..738879 (-) 660 WP_001221491.1 quorum sensing response regulator transcription factor QseB Regulator
  L1O96_RS03610 ygiW 739031..739423 (+) 393 WP_000712658.1 OB fold stress tolerance protein YgiW -
  L1O96_RS03615 ygiV 739476..739958 (+) 483 WP_000183494.1 AraC family transcriptional regulator -
  L1O96_RS03620 mqsR 740163..740459 (+) 297 WP_000415584.1 type II toxin-antitoxin system toxin MqsR -
  L1O96_RS03625 mqsA 740461..740856 (+) 396 WP_000650107.1 type II toxin-antitoxin system antitoxin MqsA -
  L1O96_RS03630 ygiS 740989..742596 (+) 1608 WP_001324265.1 ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24745.66 Da        Isoelectric Point: 6.6540

>NTDB_id=557282 L1O96_RS03605 WP_001221491.1 738220..738879(-) (ciaR) [Escherichia coli strain STEC306]
MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGRQGKEALYSAPYDAVILDLTLPGMDGRDILREWREKGQREPVLILTA
RDALAERVEGLRLGADDYLCKPFALIEVAARLEALMRRTNGQASNELRHGNVMLDPDKRIATLAGEPLTLKPKEFALLEL
LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGEK

Nucleotide


Download         Length: 660 bp        

>NTDB_id=557282 L1O96_RS03605 WP_001221491.1 738220..738879(-) (ciaR) [Escherichia coli strain STEC306]
ATGCGAATTTTACTGATAGAAGATGACATGCTGATTGGCGACGGCATCAAAACGGGCCTTAGTAAAATGGGTTTTAGCGT
CGACTGGTTTACACAAGGTCGTCAGGGAAAAGAGGCGCTTTATAGCGCACCTTATGATGCGGTGATCCTGGATTTAACCT
TACCAGGCATGGATGGTCGCGATATTTTGCGCGAATGGCGAGAAAAAGGTCAGCGTGAGCCGGTACTGATCCTGACCGCG
CGCGATGCGCTGGCGGAACGTGTAGAAGGGCTGCGTCTGGGAGCTGACGATTATCTGTGTAAACCTTTTGCGTTGATAGA
AGTCGCCGCCAGGCTGGAAGCTCTGATGCGCCGAACCAACGGCCAGGCCAGCAACGAGCTGCGCCACGGTAACGTCATGC
TCGACCCCGACAAACGTATCGCCACGCTGGCTGGCGAACCCTTAACACTGAAACCAAAAGAATTTGCCCTGCTGGAATTA
CTGATGCGTAACGCTGGTCGGGTACTGCCGCGCAAACTGATTGAAGAGAAACTGTATACCTGGGACGAAGAGGTCACCAG
TAATGCCGTTGAAGTGCATGTGCATCATCTGCGACGCAAACTCGGTAGTGATTTTATTCGTACCGTGCATGGTATTGGCT
ACACATTAGGTGAGAAATGA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-216)

Response regulator receiver domain (Response_reg)

(3-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

38.326

100

0.397
  ciaR Streptococcus pneumoniae D39

38.326

100

0.397
  ciaR Streptococcus pneumoniae R6

38.326

100

0.397
  ciaR Streptococcus pneumoniae TIGR4

38.326

100

0.397
  ciaR Streptococcus mutans UA159

35.874

100

0.365
  micA Streptococcus pneumoniae Cp1015

34.498

100

0.361