Detailed information NTG0557068

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: L1A19_RS04320
• Genome accession: NZ_CP090888
• Coordinates: 859188..860141 (+)
• Length: 317 a.a.
• NCBI ID: WP_000495909.1
• Uniprot ID: A0A0H2UPP6
• Organism: Streptococcus pneumoniae strain PT8465
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 854188..865141

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
L1A19_RS04295 (L1A19_04295)	rpmG	854931..855080 (+)	150	WP_001809104.1	50S ribosomal protein L33	-
L1A19_RS04300 (L1A19_04300)	secG	855120..855353 (+)	234	WP_000282517.1	preprotein translocase subunit SecG	-
L1A19_RS04305 (L1A19_04305)	rnr	855455..857809 (+)	2355	WP_000654920.1	ribonuclease R	-
L1A19_RS04310 (L1A19_04310)	smpB	857772..858239 (+)	468	WP_001051753.1	SsrA-binding protein SmpB	-
L1A19_RS04315 (L1A19_04315)	tehB	858255..859115 (+)	861	WP_000413769.1	SAM-dependent methyltransferase TehB	-
L1A19_RS04320 (L1A19_04320)	coiA	859188..860141 (+)	954	WP_000495909.1	competence protein CoiA	Machinery gene
L1A19_RS04325 (L1A19_04325)	pepF	860160..861962 (+)	1803	WP_000244134.1	oligoendopeptidase F	Regulator
L1A19_RS04330 (L1A19_04330)	-	861964..862677 (+)	714	WP_000230399.1	O-methyltransferase	-
L1A19_RS04335 (L1A19_04335)	prsA	862744..863685 (+)	942	WP_000727935.1	peptidylprolyl isomerase PrsA	-
L1A19_RS04340 (L1A19_04340)	-	863804..864145 (-)	342	Protein_867	IS3 family transposase	-
L1A19_RS04345 (L1A19_04345)	-	864558..864653 (+)	96	Protein_868	IS630 family transposase	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 38243.86 Da
• Isoelectric Point: 8.9865

>NTDB_id=557068 L1A19_RS04320 WP_000495909.1 859188..860141(+) (coiA) [Streptococcus pneumoniae strain PT8465]
MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTHFAHKSLKDCDFFFENESPEHLANKESLYHWLKKETK
VQLEYPLSELKQIADVFVNGNLALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTVSEDKDICRYIRQQLYYQNLFWM
KEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIEQDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE

Nucleotide

• Length: 954 bp

>NTDB_id=557068 L1A19_RS04320 WP_000495909.1 859188..860141(+) (coiA) [Streptococcus pneumoniae strain PT8465]
ATGTTTGTTGCGAGAGATGCTAGGGGAGAATTGGTAAATGTGTTAGAGGATAAACTTGAGAAGCAAGCATACACCTGCCC
AGCTTGTGGAGGCCAGCTCCATTTGCGTCAAGGACCAAGTGTACGGACGCATTTTGCCCATAAATCCTTAAAAGACTGTG
ATTTTTTCTTTGAAAATGAAAGTCCAGAACACCTGGCCAATAAGGAATCCCTCTATCACTGGTTGAAAAAAGAGACAAAG
GTTCAATTAGAGTACCCGCTTTCAGAACTTAAACAGATTGCGGATGTATTTGTAAATGGCAATCTAGCTCTAGAAGTTCA
GTGTAGTCCCTTGCCTCAGAAAGTCCTTAAAGAGCGAAGTGAGGGCTATCGTAGTCAGGGTTACCAAGTACTGTGGTTGC
TGGGTCAAAAACTGTGGCTCAAGGAGCGTTTGACTCGTCTACAGCAAGGTTTTCTTTATTTCAGTCAAAACATGGGCTTT
TATGTTTGGGAATTAGACAAGGAAAAACAAGTTTTAAGACTCAAATACCTGATTTACCAGGATCTCCGCGGTAAACTCCA
TTATCAAATCAAGGAATTTTCCTATGGTCAAGGTAGTTTATTGGAAATATTGCGTCTTCCCTATAAGAGACAAAAAATAT
CTCATTTTACAGTTTCTGAGGACAAGGACATCTGTCGCTATATCCGGCAACAACTTTATTATCAAAATCTCTTTTGGATG
AAAGAACAAGCAGAAGCCTATCAAAAGGGAGAAAATATCCTGACTTATGGACTGAAAGAATGGTATCCACAAATTCGACC
AATAGTGGGCAAATTTTTCCAGATTGAACAAGACTTGACTAGCTATTATCAGCACTTTTATACCTATTACCAAAAAAATC
CTCAAAATGATTGGCAAAAGCTTTATCCACCAGCCTTTTATCAGCAATATTTCTTGAAAAATATGGTAGAATAG

Domains

Predicted by InterProScan.

• Competence protein CoiA-like family (CoiA_nuc) (13-263)

3D structure

• AlphaFold DB: A0A0H2UPP6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus pneumoniae TIGR4	100	100	1
coiA	Streptococcus pneumoniae Rx1	99.369	100	0.994
coiA	Streptococcus pneumoniae D39	99.369	100	0.994
coiA	Streptococcus pneumoniae R6	99.369	100	0.994
coiA	Streptococcus mitis NCTC 12261	89.274	100	0.893
coiA	Lactococcus lactis subsp. cremoris KW2	42.593	100	0.435